表皮剥脱毒素
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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2018/04/02 04:02:47」(JST)
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Exfoliatin is a Staphylococcus aureus exotoxin[1] that causes a blistering of the skin known as staphylococcal scalded skin syndrome, usually in infants.[2]
Exfoliatins are glutamate-specific serine proteases highly specific to the cadherin desmoglein I, an adhesion protein in the desmosomes of the stratum granulosum that facilitates intracellular adhesion between keratinocytes. The resulting vesicles are an intraepidermal clefts between the stratum corneum and stratum spinosum and is located above the basal cells (suprabasal). A very similar non-infectious condition is seen in the autoimmune skin disorder pemphigus vulgaris in which there is an IgG antibody against the cadherin desmoglein 3.
See also
- Exfoliation (disambiguation)
- Staphylococcus aureus — Exfoliative toxins
References
- ^ Exfoliatins at the US National Library of Medicine Medical Subject Headings (MeSH)
- ^ "exfoliatin" at Dorland's Medical Dictionary
English Journal
- Molecular characteristics and virulence factors in methicillin-susceptible, resistant, and heterogeneous vancomycin-intermediate Staphylococcus aureus from central-southern China.
- Liu C1, Chen ZJ1, Sun Z2, Feng X3, Zou M4, Cao W5, Wang S6, Zeng J7, Wang Y1, Sun M1.
- Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi.J Microbiol Immunol Infect.2015 Oct;48(5):490-6. doi: 10.1016/j.jmii.2014.03.003. Epub 2014 Apr 22.
- BACKGROUND: Staphylococcus aureus is a leading cause of nosocomial infections. The purpose of this study was to evaluate the prevalence of methicillin-resistant S. aureus (MRSA) and heterogeneous vancomycin-intermediate S. aureus (hVISA), and compare the antimicrobial susceptibility, molecular chara
- PMID 24767415
- Staphylococcus aureus nasal carriage in hemodialysis centers of Fez, Morocco.
- Diawara I1, Bekhti K1, Elhabchi D2, Saile R3, Elmdaghri N4, Timinouni M4, Elazhari M4.
- Iranian journal of microbiology.Iran J Microbiol.2014 Jun;6(3):175-83.
- BACKGROUND AND OBJECTIVES: Staphylococcus aureus (S. aureus) nasal carriage may be responsible for some serious infections in hemodialyzed patients. The main target of this study was to estimate the prevalence of S. aureus nasal carriage in hemodialysis outpatients and medical staff in hemodialysis
- PMID 25870751
- Genetic lineages, antimicrobial resistance, and virulence in Staphylococcus aureus of meat samples in Spain: analysis of immune evasion cluster (IEC) genes.
- Benito D1, Gómez P, Lozano C, Estepa V, Gómez-Sanz E, Zarazaga M, Torres C.
- Foodborne pathogens and disease.Foodborne Pathog Dis.2014 May;11(5):354-6. doi: 10.1089/fpd.2013.1689. Epub 2014 Jan 30.
- The objective of this study was to determine the rate of contamination by Staphylococcus aureus in 100 meat samples obtained during 2011-2012 in La Rioja (Northern Spain), to analyze their content in antimicrobial resistance and virulence genes, as well as in immune evasion cluster (IEC) genes, and
- PMID 24479575
Japanese Journal
- ファージ I 群 52 によるブドウ球菌性熱傷様皮膚症候群の 1 例
- SSSSをとりまく諸問題-5-治療,発症機序,細菌学領域におけるSSSSおよびexfoliatinに関する報告
- A Possible Receptor Substance for Staphylococcal Exfoliatin Isolated from Mice (Symposium on Toxins)
- Japanese Journal of Medical Science and Biology 32(2), p85-88, 1979-04
- NAID 40005305639
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- 英
- exfoliatin, exfoliative toxin
- 同
- 表皮剥脱性毒素
- 関
- エクスフォリアチン、皮膚剥脱毒素
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- 英
- exfoliative toxin, ET, exfoliatin
- 関
- エクスホリアチン、伝染性膿痂疹
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- 英
- exfoliatin
- 関
- 表皮剥脱毒素、エクスフォリアチン
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- 英
- exfoliatin
- 関
- 表皮剥脱毒素、皮膚剥脱毒素