エチドカイン
WordNet
- a complex consisting of an organic base in association with hydrogen chloride
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/06/08 19:17:23」(JST)
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Etidocaine
|
Systematic (IUPAC) name |
N-(2,6-dimethylphenyl)-
2-(ethyl(propyl)amino)butanamide |
Clinical data |
Trade names |
Duranest |
AHFS/Drugs.com |
Micromedex Detailed Consumer Information |
MedlinePlus |
a603026 |
Pregnancy
category
|
- AU: B1
- US: B (No risk in non-human studies)
|
Legal status
|
|
Routes of
administration
|
Parenteral |
Pharmacokinetic data |
Bioavailability |
n/a |
Metabolism |
Hepatic |
Half-life |
2.5 hours |
Excretion |
Renal |
Identifiers |
CAS Registry Number
|
36637-18-0 N |
ATC code
|
N01BB07 |
PubChem |
CID: 37497 |
IUPHAR ligand |
2621 |
DrugBank |
DB08987 N |
ChemSpider |
34400 Y |
UNII |
I6CQM0F31V Y |
KEGG |
D04095 Y |
ChEBI |
CHEBI:4904 Y |
ChEMBL |
CHEMBL492 Y |
Chemical data |
Formula |
C17H28N2O |
Molecular mass
|
276.42 g/mol |
SMILES
- O=C(Nc1c(C)cccc1C)C(CC)N(CC)CCC
|
InChI
-
InChI=1S/C17H28N2O/c1-6-12-19(8-3)15(7-2)17(20)18-16-13(4)10-9-11-14(16)5/h9-11,15H,6-8,12H2,1-5H3,(H,18,20) Y
Key:VTUSIVBDOCDNHS-UHFFFAOYSA-N Y
|
N (what is this?) (verify) |
Etidocaine, marketed under the trade name Duranest, is a local anesthetic given by injection during surgical procedures and labor and delivery. Etidocaine has a long duration of activity, and the main disadvantage of using during dentistry is increased bleeding during surgery.[1]
References
- ^ Sisk, A. L. (1992). "Long-acting local anesthetics in dentistry". Anesthesia progress 39 (3): 53–60. PMC 2148750. PMID 1308373. edit
External links
Local anesthetics (primarily sodium channel blockers) (N01B)
|
|
Esters by acid |
Aminobenzoic
|
- Benzocaine
- Butacaine
- Butamben
- Chloroprocaine
- Dimethocaine
- Lucaine
- Meprylcaine
- Metabutethamine
- Metabutoxycaine
- Orthocaine
- Propoxycaine
- Procaine (Novocaine)
- Proxymetacaine
- Risocaine
- Tetracaine
|
|
Benzoic
|
- Amylocaine
- 3-(p-Fluorobenzoyloxy)tropane
- Cocaine
- Cyclomethycaine
- α-Eucaine
- β-Eucaine
- Hexylcaine
- Isobucaine
- Piperocaine
|
|
|
Amides |
- Articaine
- Bupivacaine # / Levobupivacaine / Ropivacaine
- Butanilicaine
- Carticaine
- Dibucaine
- Etidocaine
- Lidocaine #
- Mepivacaine
- Prilocaine
- Trimecaine
|
|
Combinations |
- Lidocaine / prilocaine
- Anesthetic / vasoconstrictor
- Iontocaine
|
|
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
Index of the peripheral nervous system
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|
Description |
- Anatomy
- Nerves
- cranial
- trigeminal
- cervical
- brachial
- lumbosacral plexus
- somatosensory
- spinal
- autonomic
- Physiology
- reflexes
- proteins
- neurotransmitters
- transporters
- Development
|
|
Disease |
- Autonomic
- Congenital
- Injury
- Neoplasms and cancer
- Other
- Symptoms and signs
|
|
Treatment |
- Procedures
- Local anesthetics
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|
|
UpToDate Contents
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English Journal
- Spectrophotometric determination of etidocaine in pharmaceutical (dental) formulation.
- Silva N1, Schapoval EE.
- Journal of pharmaceutical and biomedical analysis.J Pharm Biomed Anal.2002 Jul 20;29(4):749-54.
- A spectrophotometric method was developed for the determination of etidocaine hydrochloride (EH) in injectable pharmaceutical preparation. The proposal of this work was to develop a rapid, simple, inexpensive, precise and accurate visible spectrophotometric method. The method is based on the formati
- PMID 12093505
- Diffusive transport properties of some local anesthetics applicable for iontophoretic formulation of the drugs.
- Brounéus F1, Karami K, Beronius P, Sundelöf L.
- International journal of pharmaceutics.Int J Pharm.2001 May 7;218(1-2):57-62.
- As part of a general study to improve the iontophoretic delivery of local anaesthetics of the amide type, the diffusion properties of the hydrochloride salts of bupivacaine, etidocaine, lidocaine, mepivacaine, prilocaine and ropivacaine, were studied in a 1% w/w agarose hydrogel. A source drug solut
- PMID 11337149
- Anesthetic efficacy and heart rate effects of the intraosseous injection of 1.5% etidocaine (1:200,000 epinephrine) after an inferior alveolar nerve block.
- Stabile P1, Reader A, Gallatin E, Beck M, Weaver J.
- Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics.Oral Surg Oral Med Oral Pathol Oral Radiol Endod.2000 Apr;89(4):407-11.
- OBJECTIVE: The purpose of this study was to determine the anesthetic efficacy and heart rate effects of an intraosseous (IO) injection of 1.5% etidocaine with 1:200,000 epinephrine after an inferior alveolar nerve block.STUDY DESIGN: In a repeated-measures designed study, 48 subjects randomly receiv
- PMID 10760722
Related Links
- etidocaine [ĕ-te´do-kān] 1. a local anesthetic of the amide type, used as the hydrochloride salt for percutaneous infiltration anesthesia, peripheral nerve block, and caudal and epidural block. 2. a local anesthetic used as the ...
- ETIDOCAINE HYDROCHLORIDE ; Cat no.: API0002648 ; CAS no: 36637-19-1 ; Therapeutic: ; Indication: ; Use: API ; Target: Change Language English Afrikaans - Afrikaans Albanian - Shqiptar Arabic - العربية Basque - Euskal ...
Related Pictures
★リンクテーブル★
[★]
- 英
- etidocaine
- 化
- 塩酸エチドカイン etidocaine hydrochloride
[★]
塩酸塩、ハイドロクロライド