ectopic calcification

異所性石灰化

WordNet

1. a process that impregnates something with calcium (or calcium salts)
2. an inflexible and unchanging state; "the calcification of negotiations"
3. tissue hardened by deposition of lime salts
4. exhibiting ectopia

PrepTutorEJDIC

1. 石灰化 / (生物の組織内などの)石灰沈着;　石灰像

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/05/23 03:58:06」(JST)

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[Wiki en表示]

Ectopic calcification is a pathologic deposition of calcium salts in tissues or bone growth in soft tissues. This can be a symptom of hyperphosphatemia. Formation of osseous tissue in soft tissues such as the lungs, eyes, arteries, or other organs is known as ectopic calcification, dystrophic calcification, or ectopic ossification.

Causes

Absorption of calcium salts normally occurs in bony tissues and is facilitated by parathyroid hormone and vitamin D. However, increased amounts of parathyroid hormone in the blood result in the deposit of calcium in soft tissues. This can be an indication of hyperparathyroidism, arteriosclerosis, or trauma to tissues.

Calcification of muscle can occur after traumatic injury and is known as myositis ossificans. It can be recognized by muscle tenderness and loss of stretch in the affected area. To reduce the risk of calcification after an injury, initiate what is commonly known as "RICE" (rest, ice, compression, and elevation).

Prognosis

Ectopic ossification of the heart valves is an indicator of future heart problems, hyperparathyroidism, and necrosis of tissues.

References

UpToDate Contents

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• 1. 慢性腎臓病における血管石灰化 vascular calcification in chronic kidney disease
• 2. カルシフィラキシス（calcific uremic arteriolopathy） calciphylaxis calcific uremic arteriolopathy
• 3. 慢性腎疾患における血管石灰化の生物学 biology of vascular calcification in chronic kidney disease
• 4. 低カルシウム血症の臨床症状 clinical manifestations of hypocalcemia
• 5. 母斑性基底細胞癌症候群 nevoid basal cell carcinoma syndrome

English Journal

• The demise of calcium-based phosphate binders-is this appropriate for children?

• Rees L1, Shroff R2.
• Pediatric nephrology (Berlin, Germany).Pediatr Nephrol.2015 Dec;30(12):2061-71. doi: 10.1007/s00467-014-3017-y. Epub 2014 Dec 28.
• In children with chronic kidney disease (CKD) optimal control of mineral and bone disorder (MBD) is essential not only for the prevention of debilitating skeletal complications and for achieving adequate growth, but also for preserving long-term cardiovascular health. The growing skeleton is particu
• PMID 25543193

• Estrogen-Related Receptor γ Plays a Key Role in Vascular Calcification Through the Upregulation of BMP2 Expression.

• Kim JH1, Choi YK1, Do JY1, Choi YK1, Ha CM1, Lee SJ1, Jeon JH1, Lee WK1, Choi HS1, Park KG2, Lee IK2.
• Arteriosclerosis, thrombosis, and vascular biology.Arterioscler Thromb Vasc Biol.2015 Nov;35(11):2384-90. doi: 10.1161/ATVBAHA.115.306102. Epub 2015 Sep 24.
• OBJECTIVE: Vascular calcification which refers to ectopic mineralization in vascular cells is associated with several conditions, such as chronic kidney disease, atherosclerosis, and diabetes mellitus. Estrogen-related receptor (ERR)γ is a member of the orphan nuclear receptor superfamily, which pl
• PMID 26404484

• Molecular mechanisms of skeletal muscle development, regeneration, and osteogenic conversion.

• Endo T1.
• Bone.Bone.2015 Nov;80:2-13. doi: 10.1016/j.bone.2015.02.028.
• Both skeletal muscle and bone are of mesodermal origin and derived from somites during embryonic development. Somites differentiate into the dorsal dermomyotome and the ventral sclerotome, which give rise to skeletal muscle and bone, respectively. Extracellular signaling molecules, such as Wnt and S
• PMID 26453493

Japanese Journal

• 血液透析施行中の患者の特徴:—四肢切断と関連して—

• 日本義肢装具学会誌 31(1), 71-76, 2015
• NAID 130005120581

• Rapid Progression of Vascular and Soft Tissue Calcification while Being Managed for Severe and Persistent Hypocalcemia Induced by Denosumab Treatment in a Patient with Multiple Myeloma and Chronic Kidney Disease

• Internal Medicine 54(20), 2637-2642, 2015
• NAID 130005103200

• 軟部組織内に多発異所性骨化を伴った静脈性潰瘍の1 例

• 静脈学 26(3), 244-250, 2015
• NAID 130005094973

Related Links

• Ectopic Calcification | GreenMedInfo | Disease | Natural Medicine

Greenmedinfo.com - Natural Health Resource - The world's most widely referenced, open access, natural medicine database, with 20,000+ study abstracts and growing daily ... Member Page View Enabled You are currently viewing ...

• Ectopic calcification - RightDiagnosis.com

Ectopic calcification information including symptoms, causes, diseases, symptoms, treatments, and other medical and health issues. ... Introduction: Ectopic calcification Description of Ectopic calcification Ectopic calcification: Pathologic deposition of calcium salts in tissues.

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★リンクテーブル★

リンク元	「異所性石灰化」「転移性石灰化」
関連記事	「ectopic」「calcification」

「異所性石灰化」

　　[★]

英

ectopic calcification

関

転移性石灰化 metastatic calcification、カルシウムリン積、腎性骨異栄養症

• 例えば、腎不全により活性化ビタミンD3の産生が低下すると、血中カルシウム濃度が低下して続発性副甲状腺機能亢進症を来たす。骨吸収が亢進してカルシウムが動員され、また腎不全による高リン酸血症とにより種々の部位でリン酸カルシウムの沈着をきたす。予防にはビタミンDの投与や高リン酸血症のコントロール(P吸着、蛋白摂取制限)が必要となる。(YN.E-34 出典不明情報)

「転移性石灰化」

　　[★]

英

metastatic calcification

同

異所性カルシウム沈着、異所性石灰化 ectopic calcification、石灰転移 calcareous metastasis

「ectopic」

　　[★]

ectoより

• adj.

• 異所性の

関

allopatric、ectopically、heterotopic、heterotropic

　

「calcification」

　　[★] 石灰沈着