WordNet

excrete perspiration through the pores in the skin; "Exercise makes one sweat" (同)sudate, perspire
condensation of moisture on a cold surface; "the cold glasses were streaked with sweat"
any of various organs that synthesize substances needed by the body and release it through ducts or directly into the bloodstream (同)secretory organ, secretor, secreter
(of exocrine glands) producing a clear aqueous secretion without releasing part of the secreting cell; important in regulating body temperature

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〈U〉『汗』 / 〈U〉(一般に,物の表面にできる)湿気,露,水滴 / 〈U〉《しばしばa ~》発汗[状態];〈C〉発汗作用 / 〈U〉《しばしばa ~》《話》心配(いらだち,怒り)の状態 / 〈U〉《しばしばa ~》骨折り,つらい労働 / 『汗をかく』 / (一般に,物の表面が)湿気を帯びる,汗をかく / 《話》汗水流して働く / 〈水分〉‘を'毛穴などから出す / …‘に'汗をかかせる / 〈体重など〉‘を'汗を流して減らす《+away(off)+名,+away(off)+名》 / …から水分を出させる / 〈人・馬など〉‘を'汗水流して働かせる,酷使する
(生物体内の)腺(せん)
(比較変化なし)《名詞の前にのみ用いて》低賃金で重労働を強いられた

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/11/24 10:11:31」(JST)

wiki en

Eccrine glands (/ˈɛkrən/, /ˈɛˌkraɪn/, or /ˈɛˌkrin/; from ekkrinein "secrete";^[3] sometimes called merocrine glands) are the major sweat glands of the human body, found in virtually all skin, with the highest density in palms and soles, then on the head, but much less on the trunk and the extremities. In lower mammals, they are relatively sparse, being found mainly on hairless areas such as foot pads. They reach their peak of development in humans, where they may number 200–400/cm² of skin surface.^[4]^[5] They produce a clear, odorless substance, consisting primarily of water and NaCl. NaCl is reabsorbed in the duct to reduce salt loss,^[6] but is dysfunctional in cystic fibrosis thus producing salty sweat. They are active in thermoregulation by providing cooling from water evaporation of sweat secreted by the glands on the body surface and emotional induced sweating (anxiety, fear, stress, and pain).^[5]^[7] The white sediment in otherwise colorless eccrine secretions is caused by evaporation that increases the concentration of salts.

The odour from sweat is due to bacterial activity on the secretions of the apocrine sweat glands, a distinctly different type of sweat gland found in human skin.

Eccrine glands are composed of an intraepidermal spiral duct, the "acrosyringium"; a dermal duct, comprising a straight and coiled portion; and a secretory tubule, coiled deep in the dermis or hypodermis.^[7] The eccrine gland opens out through the sweat pore. The coiled portion is formed by single layer of columnar or cuboidal epithelial cells, which are secretory in nature. The epithelial cells are interposed by the myoepithelial cells. Myoepithelial cells support the secretory epithelial cells. The duct of eccrine gland is formed by two layers of cuboidal epithelial cells. Eccrine glands are innervated by the sympathetic nervous system, primarily by cholinergic fibers whose discharge is altered primarily by changes in deep body temperature (core temperature), but by adrenergic fibers as well.^[8] The glands on palms and soles do not respond to temperature but secrete at times of emotional stress.

Secretion

Eccrine glands function from birth throughout life. The secretion of eccrine glands is a sterile, dilute electrolyte solution with primary components of bicarbonate, potassium, and sodium chloride (NaCl),^[5] and other minor components such as glucose, pyruvate, lactate, cytokines, immunoglobulins, antimicrobial peptides (e.g., dermcidin), and many others.^[5] Dermcidin is a newly isolated antimicrobial peptide produced by the eccrine sweat glands.^[9]

References

^ ^a ^b Neas, John F. "Development of the Integumentary System". In Martini, Frederic H.; Timmons, Michael J.; Tallitsch, Bob. Embryology Atlas (4th ed.). Benjamin Cumings. Retrieved 17 December 2012.
^ Krstic, Radivoj V. (18 March 2004). Human Microscopic Anatomy: An Atlas for Students of Medicine and Biology. Springer. p. 464. ISBN 9783540536666.
^ "eccrine". The New Oxford American Dictionary (2 ed.). 2005. ISBN 9780195170771.
^ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology (10th ed.). Saunders. pp. 6–7. ISBN 0-7216-2921-0.
^ ^a ^b ^c ^d Bolognia, J., Jorizzo, J., & Schaffer, J. (2012). Dermatology (3rd ed., pp. 539-544). [Philadelphia]: Elsevier Saunders.
^ Mauro, Theodora M; Goldsmith, Lowell A. "Biology of Eccrine, Apocrine, and Apoeccrine Sweat Glands". In Wolff, K; Goldsmith, LA; Katz, SI; Gilchrest, B; Paller, AS; Leffell, DJ. Fitzpatrick's Dermatology in General Medicine.
^ ^a ^b Wilke, K.; Martin, A.; Terstegen, L.; Biel, S. S. (June 2007). "A short history of sweat gland biology" (pdf). International Journal of Cosmetic Science. 29 (3): 169–179. doi:10.1111/j.1467-2494.2007.00387.x. ISSN 1468-2494.
^ Sokolov, VE; Shabadash, SA; Zelikina, TI (1980). "Innervation of eccrine sweat glands". Biology Bulletin of the Academy of Sciences of the USSR. 7 (5): 331–46. PMID 7317512.
^ Niyonsaba, F; Suzuki, A; Ushio, H; Nagaoka, I; Ogawa, H; Okumura, K (2009). "The human antimicrobial peptide dermcidin activates normal human keratinocytes". The British journal of dermatology. 160 (2): 243–9. doi:10.1111/j.1365-2133.2008.08925.x. PMID 19014393.

External links

American Academy of Dermatology – Eccrine and Apocrine Glands

UpToDate Contents

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1. 唾液腺腫瘍：限局性疾患の治療 salivary gland tumors treatment of locoregional disease
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3. 好中球性皮膚症 neutrophilic dermatoses
4. 唾石症 salivary gland stones
5. シェーグレン症候群の臨床症状：外分泌腺障害 clinical manifestations of sjogrens syndrome exocrine gland disease

English Journal

Apocrine Hidrocystoma of the Lower Lip: A Case Report and Literature Review.

Kikuchi K, Fukunaga S, Inoue H, Miyazaki Y, Ide F, Kusama K.SourceDivision of Pathology, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry, 1-1 Keyakidai, Sakado, Saitama, 350-0283, Japan, k-kikuchi@dent.meikai.ac.jp.
Head and neck pathology.Head Neck Pathol.2013 Jun 6. [Epub ahead of print]
The hidrocystomas (HCs) are cystic forms of sweat gland resulting from proliferation of the apocrine secretory coil or eccrine duct. Apocrine -HCs are cystic lesions that arise from the apocrine secretory coil, while eccrine -HCs represent retention cysts of the eccrine duct. The commonest site for
PMID 23740163

Distinctive histopathologic findings in linear morphea (en coup de sabre) alopecia.

Pierre-Louis M, Sperling LC, Wilke MS, Hordinsky MK.SourceDepartment of Dermatology, University of Minnesota Medical School, Minneapolis, MN, USA.
Journal of cutaneous pathology.J Cutan Pathol.2013 Jun;40(6):580-4. doi: 10.1111/cup.12124. Epub 2013 Mar 18.
Linear morphea en coup de sabre is a localized form of morphea that presents as paramedian face or frontal scalp depression. The histopathology of alopecia in linear morphea is typically characterized by sclerosis and a reduction in the number of follicular units. We present a 26-year-old Caucasian
PMID 23506089

Potential diagnostic pitfall in direct immunofluorescence evaluation for vasculitis in skin biopsies: fluorescent secretory granules within eccrine glands.

Lehman JS, Camilleri MJ.SourceDivision of Dermatopathology and Cutaneous Immunopathology, Department of Dermatology, Mayo Clinic, Rochester, MN, USA.
Journal of cutaneous pathology.J Cutan Pathol.2013 Jun;40(6):603-5. doi: 10.1111/cup.12111. Epub 2013 Mar 8.
PMID 23472657

Japanese Journal

A Case of Primary Signet-Ring Cell/Histiocytoid Carcinoma of the Eyelid: Immunohistochemical Comparison With the Normal Sweat Gland and Review of the Literature

Iwaya Mai,Uehara Takeshi,Yoshizawa Akihiko,Kobayashi Yukihiro,Momose Masanobu,Honda Takayuki,Ota Hiroyoshi
AMERICAN JOURNAL OF DERMATOPATHOLOGY 34(8), E139-E145, 2012-12
… Primary signet-ring cell/histiocytoid carcinomas of the eyelid are extremely rare tumors considered to originate from sweat glands. … Here, we report the case of a 72-year-old man diagnosed with primary signet-ring cell/histiocytoid carcinoma of the eyelid and present immunohistochemical analyses of the eyelid apocrine gland (Moll gland) and apocrine and eccrine sweat glands of perineum and axilla. …
NAID 120005440188

発汗の機序と発汗異常を伴う疾患 (教育セミナーアクセサリーオーガンとオーラルケアの香粧品学 : エチケットのサイエンス)

横関博雄
日本香粧品学会誌 36(2), 108-113, 2012-06
NAID 40019389933

Immunolocalization of aquaporin-5 in normal human skin and hypohidrotic skin diseases

IIZUKA Takashi,SUZUKI Takao,NAKANO Kiyoko,SUEKI Hirohiko
Journal of dermatology 39(4), 344-349, 2012-04-01
NAID 10031184905

Related Pictures

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★リンクテーブル★

リンク元	「エックリン汗腺」「エクリン汗腺」
関連記事	「sweating」「eccrine」

「エックリン汗腺」

Eccrine sweat gland
	A sectional view of the skin (magnified), with eccrine glands highlighted.
Details
Precursor	Ectoderm
System	Integumentary
Nerve	Cholinergic sympathetic nerves
Identifiers
Latin	Glandula sudorifera merocrina;; Glandula sudorifera eccrina
MeSH	A10.336.899.480
TH	H3.12.00.3.03009
FMA	59154
	Anatomical terminology [edit on Wikidata]