UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 溶血性尿毒症症候群（HUS）、血栓性血小板減少性紫斑病（TTP）、またはその他の血栓性微小血管障害症（TMA）が疑われる患者に対するアプローチapproach to the patient with suspected ttp hus or other thrombotic microangiopathy tma [show details]
…topic reviews. If MAHA is not present, other acute systemic illnesses associated with pancytopenia must be considered. If MAHA is present, considerations include systemic illness or MAHA due to a mechanical …
2. 外因性非免疫性溶血性貧血：断片化溶血と脾機能亢進症extracorpuscular non immune hemolytic anemia fragmentation hemolysis and hypersplenism [show details]
…determine whether RBC fragmentation is occurring. Schistocytes (also called helmet cells) have been defined by the Schistocyte Working Group of the International Council for Standardization in Haematology …
3. 後天性TTP：臨床症状および診断acquired ttp clinical manifestations and diagnosis [show details]
…is suggestive of MAHA . The quantity of schistocytes in TTP was illustrated in a series of patients with TTP and other disorders typically associated with MAHA, in which schistocytes represented on average …
4. 後天性TTP：初期治療acquired ttp initial treatment [show details]
…patients with a thrombotic microangiopathy (TMA; inferred from thrombocytopenia and microangiopathic hemolytic anemia [MAHA]) without another obvious cause, the PLASMIC score is used to quantify the likelihood …
5. 成人の急性腎障害に伴う血栓性微小血管症thrombotic microangiopathies with acute kidney injury in adults [show details]
… The occurrence of acute kidney injury (AKI) in adults associated with microangiopathic hemolytic anemia (MAHA) and thrombocytopenia presents diagnostic and therapeutic challenges, as there are many diverse …

English Journal

Small Red Blood Cell Fraction on the UF-1000i Urine Analyzer as a Screening Tool to Detect Dysmorphic Red Blood Cells for Diagnosing Glomerulonephritis.

Kim H, Kim YO, Kim Y, Suh JS, Cho EJ, Lee HK.
Annals of laboratory medicine. 2019 05;39(3)271-277.
Dysmorphic red blood cells (dRBCs) are first-line biomarkers for detecting glomerulonephritis (GN) in patients with hematuria. The UF-1000i system (Sysmex, Kobe, Japan), based on flow cytometry, provides small red blood cell (RBC) values (UF-1000i [UF]-%sRBCs). We evaluated the clinical application
PMID 30623619

Wilson disease and lupus nephritis: is it coincidence or a true association?

Pradhan S, Krishnamurthy S, Jagadisan B, Rajesh NG, Kaliaperumal S, Ramasamy S, Subramanian N.
Paediatrics and international child health. 2019 May;39(2)146-149.
A 12-year-old girl born to third-degree consanguineous parents presented with recurrent episodes of haematuria for 8 months in association with peri-orbital and lower limb oedema for 20 days. There was no jaundice, hepatomegaly or neurological abnormality at presentation. An older brother had died
PMID 29528784

Glomerular isolated microscopic hematuria: urinary features and long term follow-up of a selected cohort of patients.

Bellincioni C, Garigali G, Fogazzi GB.
Journal of nephrology. 2019 Apr;32(2)253-258.
Isolated microscopic hematuria is a condition characterized by the presence in the urine of an "abnormal" number of erythrocytes in the absence of proteinuria. Several studies have been published on this condition, but with heterogeneous inclusion criteria and variable outcomes at follow-up. In this
PMID 30535632

Japanese Journal

UF-1000iによる尿中赤血球形態情報の検証―尿沈渣検査法・臨床診断との比較―

愛甲佐津紀,西律子,川口路実,小橋眞規子,山田祐也
医学検査 65(4), 419-423, 2016
… RBCinfoと目視鏡検の糸球体型赤血球（G-RBC）との一致率は，Dysmorphic?（Dys）が49.1%，Mixed?（Mix）39.3%，Isomorphic?（Iso）1.2%だった。 …
NAID 130007040358

尿沈渣標本作成後の上清中の赤血球残存率と赤血球形態

寺岡千織,宮永恵美子,山下典子,生中涼子,原文子,本倉徹
医学検査 65(3), 350-353, 2016
尿沈渣標本作成過程においては，遠心操作，上清除去などの誤差要因が存在する。以前我々は，尿中有形成分分析装置の導入時の基礎的検討の際，無遠心尿を用いたフローサイトメトリー法と尿沈渣検査法の結果に赤血球数の乖離を認めたことを報告した。その原因を明らかにするために，今回我々は，尿沈渣標本作成後の上清中の赤血球残存率とその赤血球形態について検討を行った。その結果，尿沈渣検査法における遠心後の上清中には赤血 …
NAID 130005164404

尿沈渣鏡検法の内部精度管理の有用性に関する検討

石﨑大輝,伊瀬恵子,内本高之,澤部祐司,野村文夫
医学検査 63(1), 48-52, 2014
… Variabilities among the three technologists in counting red blood cell (RBC), white blood cell (WBC), and casts were found to be improved as early as five days after the start of quality control particularly in the newcomer. … The rare components including waxy cast, atypical cell, dysmorphic RBC, <i>Trichomonas vaginalis </i>were detected similarly by the three technologists. …
NAID 130005057027