- 関
- crystallographic analysis
WordNet
- an investigation of the component parts of a whole and their relations in making up the whole
- the abstract separation of a whole into its constituent parts in order to study the parts and their relations (同)analytic thinking
- a branch of mathematics involving calculus and the theory of limits; sequences and series and integration and differentiation
- a form of literary criticism in which the structure of a piece of writing is analyzed
- the use of closed-class words instead of inflections: e.g., `the father of the bride instead of `the brides father
- a solid formed by the solidification of a chemical and having a highly regular atomic structure
- a protective cover that protects the face of a watch (同)watch crystal, watch_glass
- a crystalline element used as a component in various electronic devices
- glassware made of quartz
- a rock formed by the solidification of a substance; has regularly repeating internal structure; external plane faces (同)crystallization
PrepTutorEJDIC
- (内容・状況などの)『分析』,分解;(詳細な)検討 / (化学・物理で)分析;《米》(心理学で)[精神]分析;(数学で)解析
- 〈U〉『水晶』 / 〈C〉『水晶製品』,水晶玉 / 〈U〉クリスタルグラス(透明度の高い鉛ガラス);《集合的に》クリスタルグラス製食器類(特にコップ類) / 〈C〉『結晶[体]』 / 〈C〉《米》(時計の)ガラスぶた / 『水晶[製]の』;クリスタルグラス製の;透き通った
UpToDate Contents
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English Journal
- Dissolution properties, solid-state transformation and polymorphic crystallization: progesterone case study.
- Araya-Sibaja AM, Paulino AS, Rauber GS, Campos CE, Cardoso SG, Monti GA, Heredia V, Bianco I, Beltrano D, Cuffini SL.Author information Programa de Pós-Graduação em Farmácia, Universidade Federal de Santa Catarina , Florianópolis , Brasil .AbstractAbstract Progesterone is a natural steroid hormone and a poor soluble drug which presents two polymorphs (forms 1 and 2). Different methods to obtain form 2 were tested and a complete solid-state characterization of both polymorphs (forms 1 and 2) was conducted. X-ray powder diffraction, hot stage microscopy, Fourier transform infrared, dispersive Raman, (13)C solid-state nuclear magnetic resonance spectroscopy, thermal analysis, scanning electron microscopy techniques and intrinsic dissolution rates (IDR) were applied to investigate physical-chemical and dissolution properties of these two polymorphs. Form 2 was obtained from diluted solutions and from melting after cooling at room temperature. Form 1 was obtained from concentrated solutions and, a mixture of both polymorphs was crystallized from intermediate solutions. The crystal habit was not a distinctive characteristic of each polymorph. The effect of mechanical stress was evaluated in the metastable polymorph (form 2). We observed that grinding form 2 produced seeds of form 1 that induced the transformation of form 2 into form 1 at high temperature. The polymorphic quantification from XRD patterns of ground samples were carried out by the Rietveld method. After grinding and at room temperature conditions (∼25 °C), it was observed the transformation of 17% of form 2 into form 1 in 10 days.
- Pharmaceutical development and technology.Pharm Dev Technol.2014 Nov;19(7):779-88. doi: 10.3109/10837450.2013.829096. Epub 2013 Sep 13.
- Abstract Progesterone is a natural steroid hormone and a poor soluble drug which presents two polymorphs (forms 1 and 2). Different methods to obtain form 2 were tested and a complete solid-state characterization of both polymorphs (forms 1 and 2) was conducted. X-ray powder diffraction, hot stage m
- PMID 24032356
- Fast disintegrating tablets of nisoldipine for intra-oral administration.
- El Maghraby GM, Elsergany RN.Author information Department of Pharmaceutical Technology, College of Pharmacy, University of Tanta , Tanta , Egypt.AbstractAbstract Nisoldipine is a calcium channel blocker with low and variable oral bioavailability. This was attributed to slow dissolution and presystemic metabolism. Accordingly, the objective of this work was to enhance the dissolution rate of nisoldipine to formulate fast disintegrating tablets with rapid dissolution. Binary solid dispersions (SD) were prepared for the drug with hydroxypropyl methyl cellulose E5 (HPMC), polyvinylpyrrolidone (PVP), Pluronic F68 or polyethylene glycol 6000 (PEG 6000). SD formation increased the dissolution rate compared to pure drug with the corresponding physical mixtures failing to provide the same dissolution enhancement. This indicates that the SD enhanced dissolution is not due to the solubilizing effect of the polymer and can be due to physical change in the drug crystal which was confirmed by thermal analysis. SD with HPMC and PVP were selected for preparation of fast disintegrating tablets as they liberated most of the drug in the first 5 min. HPMC-based tablets disintegrated rapidly and released most of the drug in the first 2 min which correlated with the corresponding SD. In contrast, PVP-based tablets disintegrated slowly with gradual dissolution. This can be attributed to the binding effect of PVP. The study developed fast disintegrating tablet for intra-oral administration.
- Pharmaceutical development and technology.Pharm Dev Technol.2014 Sep;19(6):641-50. doi: 10.3109/10837450.2013.813543. Epub 2013 Jul 10.
- Abstract Nisoldipine is a calcium channel blocker with low and variable oral bioavailability. This was attributed to slow dissolution and presystemic metabolism. Accordingly, the objective of this work was to enhance the dissolution rate of nisoldipine to formulate fast disintegrating tablets with r
- PMID 23841582
- A sensitive quartz crystal microbalance assay of adenosine triphosphate via DNAzyme-activated and aptamer-based target-triggering circular amplification.
- Song W, Zhu Z, Mao Y, Zhang S.Author information Key Laboratory of Biochemical Analysis, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, PR China.AbstractIn this work, a simple and novel quartz crystal microbalance (QCM) assay is demonstrated to selectively and sensitively detect the adenosine triphosphate (ATP). The amplification process consists of circular nucleic acid strand-displacement polymerization, aptamer recognition strategy and nanoparticle signal amplification. With the involvement of an aptamer-based complex, two amplification reaction templates and AuNP-functionalized probes, the whole circle amplification process is triggered by the target recognition of ATP. As an efficient mass amplifier, AuNP-functionalized probes are introduced to enhance the QCM signals. As a result of DNA multiple amplification, a large number of AuNP-functionalized probes are released and hybridized with the capture probes on the gold electrode. Therefore the QCM signals are significantly enhanced, reaching a detection limit of ATP as low as 1.3 nM. This strategy can be conveniently used for any aptamer-target binding events with other biological detection such as protein and small molecules. Moreover, the practical determination of ATP in cancer cells demonstrates the feasibility of this QCM approach and potential application in clinical diagnostics.
- Biosensors & bioelectronics.Biosens Bioelectron.2014 Mar 15;53:288-94. doi: 10.1016/j.bios.2013.09.067. Epub 2013 Oct 8.
- In this work, a simple and novel quartz crystal microbalance (QCM) assay is demonstrated to selectively and sensitively detect the adenosine triphosphate (ATP). The amplification process consists of circular nucleic acid strand-displacement polymerization, aptamer recognition strategy and nanopartic
- PMID 24161526
Japanese Journal
- Syntheses and Redox Properties of Complexes with Mo3S4 Cores and Tridentate Schiff Base Ligands
- Kawamoto Keisuke,Ichimura Akio,Hashimoto Hideki,Kinoshita Isamu,Nishioka Takanori
- Bulletin of the Chemical Society of Japan, 2015
- … Single crystal X-ray structural analysis of 1-PF6 revealed that one Schiff base ligand coordinates to each Mo via the O, N, and SMe donor atoms, and then the mono cationic cluster [Mo3S4(LSMe)3]+ has a pseudo C3 symmetry if the chirality around the coordinated sulfur atoms is not taken into account. …
- NAID 130004712924
- Aqueous Phase Behavior of the Rare Monosaccharide D-Allose and X-ray Crystallographic Analysis of D-Allose Dihydrate
- Kozakai Taro,Fukada Kazuhiro,Kuwatori Ryu,Ishii Tomohiko,Senoo Tatsuya,Izumori Ken
- Bulletin of the Chemical Society of Japan, 2015
- … X-ray single crystal analysis confirmed that D-All molecules in the dihydrate form a β-D-pyranose ring in 4C1 conformation. … The crystal system (orthorhombic), space group (P212121, #19), and number of sugar molecules per unit cell (Z = 4) were the same as those of D-All anhydride (stable Form I). …
- NAID 130004703953
- Odd-Even Effect Observed in [Ni(dmit)2] Complex Salts of Quaternary Ammonium Cation with Both Benzyl Groups and ω-Phenylalkyl Groups
- Saeki Masahiro,Dai Kotaro,Ichimura Shuhei,Tamaki Yoshinori,Tomono Kazuaki,Miyamura Kazuo
- Bulletin of the Chemical Society of Japan, 2015
- … n = 1-4) have been prepared and characterized by X-ray crystallographic structural analysis. … Other BnCnPh complex salts adopt herringbone structure.<BR>Interestingly, BnCnPh series (n = 1, 2, 3α, 4) exhibit three types of pronounced odd-even effect in the crystal structures; … Introduction of terminal phenyl group is concluded to have increased the steric effect and led to the formation of novel crystal structure of [Ni(dmit)2] complex salts. …
- NAID 130004703949
Related Links
- X線による結晶の解析プログラム作成 Programs for Crystal Analysis by X-ray For Single Crystal * Laue Analysis System
- Crystal Analysis / Crystal Enterprise / Crystal Reports Crystal Analysis / Crystal Enterprise は 2006年9月22日、Crystal Reports は 2009年12月26日をもちまして、販売を終了しております。Crystal Reports ...
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- 英
- crystallographic analysis、crystal analysis
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- 関
- crystal analysis
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- 関
- anal、analyse、analyses、analytical、analyze、assay、dissect、-metry、solve
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