関: adenosylcobalamin

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/05/08 13:26:50」(JST)

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Cobamamide (AdoCbl), which is also known as adenosylcobalamin and dibencozide, is, along with methylcobalamin (MeCbl), one of the active forms of vitamin B₁₂. As a nutritional supplement, it is available in tabletted form, but, (unlike cyanocobalamin, methylcobalamin, and hydroxocobalamin), it is not available in injectable form.

An enzyme that uses adenosylcobalamin as a cofactor is methylmalonyl-CoA mutase (MCM).

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B03BA04

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English Journal

Quantification of cyproheptadine in human plasma by high-performance liquid chromatography coupled to electrospray tandem mass spectrometry in a bioequivalence study.

Mendes GD, Arruda A, Chen LS, Almeida Magalhaes JC, Alkharfy KM, De Nucci G.SourceDepartment of Pharmacology, State University of Campinas, Campinas, Brazil; Galeno Research Unit, Campinas, Brazil; Faculty of Odontology, University Camilo Castelo Branco (UNICASTELO), Sao Paulo, Brazil. gugamendes@terra.com.br.
Biomedical chromatography : BMC.2011 Mar 23. doi: 10.1002/bmc.1618. [Epub ahead of print]
A rapid, sensitive and specific method to quantify cyproheptadine in human plasma using amitriptyline as the internal standard (IS) is described. The analyte and the IS were extracted from plasma by liquid-liquid extraction using a diethyl-ether/dichloromethane (70/30; v/v) solvent. After removing a
PMID 21432861

Genetic analysis of the protein shell of the microcompartments involved in coenzyme B12-dependent 1,2-propanediol degradation by Salmonella.

Cheng S, Sinha S, Fan C, Liu Y, Bobik TA.SourceIowa State University, Department of Biochemistry, Biophysics and Molecular Biology, Ames, IA 50011, USA.
Journal of bacteriology.2011 Mar;193(6):1385-92. Epub 2011 Jan 14.
Hundreds of bacterial species use microcompartments (MCPs) to optimize metabolic pathways that have toxic or volatile intermediates. MCPs consist of a protein shell encapsulating specific metabolic enzymes. In Salmonella, an MCP is used for 1,2-propanediol utilization (Pdu MCP). The shell of this MC
PMID 21239588

Japanese Journal

アスコルビン酸の輸液中での安定性

山路昭,大島孝一,大西昇,紀氏汎恵,平岡栄一
病院薬学 6(4), 251-256, 1981-02-20
… Among these injections, the following increased significantly the oxidation of AsA in infusion solution : 20mg riboflavin phosphate sodium (B_2), 10mg flavin adenin dinucleotide phosphate, 30 mg Pyridoxal phosphate, 1,000μg hydroxocobalamin, 500μg cobamamide, multi-vitamin injection (Vitamedin, Vitaneurin) and trace element injection for intravenous hyperalimentation (IVH-M_2). …
NAID 110001796796

Cobamamide(Calomide山之内)の臨床的観察

野呂忠慈 [他]
診療 22(2), 243-247, 1969-02
NAID 40017934462

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リンク元	「コバマミド」「adenosylcobalamin」

「コバマミド」

Cobamamide
Systematic (IUPAC) name
	Coα-[α-(5,6-dimethylbenzimidazolyl)]-Coβ-; (5'-deoxy-5'-adenosyl)cobamide
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy cat.	?
Legal status	OTC (US)
Identifiers
CAS number	13870-90-1
ATC code	B03BA04
PubChem	CID 5459907
ChemSpider	16736117
KEGG	D00042
Chemical data
Formula	C72H100CoN18O17P
Mol. mass	1579.58 g/mol
	InChI InChI=1S/C62H90N13O14P.C10H12N5O3.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;1-4-6(16)7(17)10(18-4)15-3-14-5-8(11)12-2-13-9(5)15;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);2-4,6-7,10,16-17H,1H2,(H2,11,12,13);/q;;+2/p-2/t31?,34?,35?,36?,37?,41-,52-,53-,56?,57+,59?,60?,61?,62?;4-,6-,7-,10-;/m11./s1 ; Key:ZIHHMGTYZOSFRC-CXGXMSGESA-L ;
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