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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2017/04/08 20:56:58」(JST)

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1. 肥大型心筋症における内科的治療 medical therapy in hypertrophic cardiomyopathy

English Journal

Andersen-Tawil syndrome associated with aborted sudden cardiac death: atrial pacing was effective for ventricular arrhythmias.

Kuramoto Y, Furukawa Y, Yamada T, Okuyama Y, Fukunami M.SourceDivision of Cardiology, Osaka General Medical Center, Osaka, Japan.
The American journal of the medical sciences.Am J Med Sci.2012 Sep;344(3):248-50. doi: 10.1097/MAJ.0b013e3182560209.
A 37-year-old Japanese woman experienced aborted sudden cardiac death from ventricular fibrillation and was diagnosed with Andersen-Tawil syndrome by genetic analysis that revealed 2 mutations in the KCNJ2 gene. Although she received an implantation of implantable cardioverter defibrillator and beta
PMID 22739561

Agranulocytosis immediately after oral administration of cibenzoline and dabigatran in a patient with paroxysmal atrial fibrillation.

Hayashi H, Kitoh K, Mitsunami K, Horie M.SourceDepartment of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Japan. hayashih@belle.shiga-med.ac.jp
Internal medicine (Tokyo, Japan).Intern Med.2012;51(15):1987-90. Epub 2012 Aug 1.
This case report describes agranulocytosis immediately after oral administration of cibenzoline and dabigatran in a 70-year-old woman with paroxysmal atrial fibrillation (AF). No blasts were found in peripheral blood and bone marrow, and the white blood cell count increased abruptly by intravenous a
PMID 22864123

Japanese Journal

Inhibitory Effect of Cibenzoline on Na^+/Ca^<2+> Exchange Current in Guinea-Pig Cardiac Ventricular Myocytes

YAMAKAWA Tomomi,WATANABE Yasuhide,WATANABE Hiroshi,KIMURA Junko
Journal of pharmacological sciences 120(1), 59-62, 2012-09-20
NAID 10031071977

Agranulocytosis Immediately after Oral Administration of Cibenzoline and Dabigatran in a Patient with Paroxysmal Atrial Fibrillation

Hayashi Hideki,Kitoh Katsuyuki,Mitsunami Kenichi,Horie Minoru
Internal Medicine 51(15), 1987-1990, 2012
… This case report describes agranulocytosis immediately after oral administration of cibenzoline and dabigatran in a 70-year-old woman with paroxysmal atrial fibrillation (AF). … No blasts were found in peripheral blood and bone marrow, and the white blood cell count increased abruptly by intravenous administration of granulocyte colony-stimulation factor, suggesting an allergic response caused by cibenzoline or dabigatran, or both. …
NAID 130002062272

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★リンクテーブル★

リンク元	「シベンゾリン」
拡張検索	「cibenzoline succinate」

「シベンゾリン」

Cibenzoline
Names
	IUPAC name 2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1H-imidazole
Identifiers
CAS Number	53267-01-9;
3D model (Jmol)	Interactive image;
ChemSpider	2645;
ECHA InfoCard	100.053.122
KEGG	D03492;
PubChem CID	2747;
UNII	Z7489237QT ;
	InChI InChI=1/C18H18N2/c1-3-7-14(8-4-1)18(15-9-5-2-6-10-15)13-16(18)17-19-11-12-20-17/h1-10,16H,11-13H2,(H,19,20) Key: IPOBOOXFSRWSHL-UHFFFAOYAC ;
	SMILES N\1=C(\NCC/1)C4CC4(c2ccccc2)c3ccccc3 ;
Properties
Chemical formula	C18H18N2
Molar mass	262.35 g/mol
Pharmacology
ATC code	C01BG07 (WHO)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
	Infobox references