WordNet

being long-lasting and recurrent or characterized by long suffering; "chronic indigestion"; "a chronic shortage of funds"; "a chronic invalid"
of long duration; "chronic money problems" (同)continuing
habitual; "a chronic smoker" (同)inveterate
any painful disorder of the joints or muscles or connective tissues

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1. 慢性蕁麻疹：難治性症状の治療 chronic urticaria treatment of refractory symptoms
2. 慢性蕁麻疹：標準的なマネージメントおよび患者教育 chronic urticaria standard management and patient education
3. 女性における慢性骨盤痛の原因 causes of chronic pelvic pain in women
4. 慢性閉塞性肺疾患（COPD）：定義、臨床症状、診断、および病期分類 chronic obstructive pulmonary disease definition clinical manifestations diagnosis and staging
5. 慢性骨髄性白血病の臨床症状および診断 clinical manifestations and diagnosis of chronic myeloid leukemia

Szolga B, Filipescu I, Damian L, Rednic S, Rednic N.Author information Rheumatology Department, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.AbstractINTRODUCTION: Macrophage activation syndrome is a rare and potentially life threatening condition, triggered by various events like bacterial and viral illness and sometimes it can be a complication of childhood rheumatic disorders. Physical and laboratory results usually show non-remitting fever, hepatosplenomegaly, lymphadenopathy, bleeding diathesis, altered mental status, rash, pancytopenia and impaired liver and renal function tests, elevated triglyceride and serum ferritin levels. Corticosteroids and Cyclosporine are the drugs commonly used in its management. Early diagnosis and prompt treatment can be life saving.
Annals of the rheumatic diseases.Ann Rheum Dis.2014 Mar 1;73 Suppl 1:A92. doi: 10.1136/annrheumdis-2013-205124.214.
INTRODUCTION: Macrophage activation syndrome is a rare and potentially life threatening condition, triggered by various events like bacterial and viral illness and sometimes it can be a complication of childhood rheumatic disorders. Physical and laboratory results usually show non-remitting fever, h
PMID 24489348

Meirinhos T, Aguiar R, Ambrósio C, Barcelos A.Author information Rheumatology Department, CHBV- Aveiro, Portugal.AbstractINTRODUCTION: Pain is the most common symptom in rheumatic diseases. In its pathophysiology there is usually a disturbance in nociceptive perception by tissue damage, that evolve often to features of central pain, with characteristics of neuropathic pain (NP). Neuropathic pain in rheumatic diseases is a topic rarely addressed in the literature.
Annals of the rheumatic diseases.Ann Rheum Dis.2014 Mar 1;73 Suppl 1:A76. doi: 10.1136/annrheumdis-2013-205124.174.
INTRODUCTION: Pain is the most common symptom in rheumatic diseases. In its pathophysiology there is usually a disturbance in nociceptive perception by tissue damage, that evolve often to features of central pain, with characteristics of neuropathic pain (NP). Neuropathic pain in rheumatic diseases
PMID 24489303

A5.16 miRNA expression profile in Bulgarian patients with rheumatoid arthritis compared to patients with osteoarthritis and healthy controls in regard to their use as biomarkers in the clinical practice.

Shumnalieva R, Kachakova D, Monov S, Kaneva R, Kolarov Z, Rashkov R.Author information Medical University - Sofia, Department of Internal Medicine, Clinic of Rheumatology.AbstractBACKGROUND AND OBJECTIVES: The pathogenesis of rheumatoid arthritis (RA) is still unknown. Recent data suggest that micro-ribonucleic acids (microRNAs) and their targets are involved in the inflammatory process and may perpetuate the chronic joint involvement. The aim of the study is to compare the expression of certain microRNA in peripheral blood and synovial fluid in Bulgarian patients with RA in relation to their clinical picture and laboratory data. The expression profile of RA samples was compared with samples from patients with osteoarthritis (OA) and healthy controls (HCs). The chosen microRNAs were analysed in regard to their use as biomarkers for disease activity and progression.
Annals of the rheumatic diseases.Ann Rheum Dis.2014 Mar 1;73 Suppl 1:A69. doi: 10.1136/annrheumdis-2013-205124.158.
BACKGROUND AND OBJECTIVES: The pathogenesis of rheumatoid arthritis (RA) is still unknown. Recent data suggest that micro-ribonucleic acids (microRNAs) and their targets are involved in the inflammatory process and may perpetuate the chronic joint involvement. The aim of the study is to compare the
PMID 24489285

米森雅也,速見浩士,松下良介 [他],大橋保,谷口賢二郎,牟田裕美,佐潟芳久,山田保俊,榎田英樹,中川昌之
日本透析医学会雑誌 = Journal of Japanese Society for Dialysis Therapy 45(6), 501-505, 2012-06-28
症例は73歳，女性．高血圧，糖尿病，慢性関節リウマチ，慢性腎不全の診断にて前医で外来治療を受けていた．2007年6月から全身性の浮腫が増悪し，貧血の悪化と腎不全が進行したため前医に入院し，血液透析へ導入された．透析導入後のバスキュラーアクセスは両側大腿静脈の直接穿刺が施行されていたが，穿刺部である左大腿部に巨大な血腫が生じ，同時に左膝関節内出血と消化管出血が認められた．血液検査にて活性化部分トロン …
NAID 10030814242