WordNet

without undue constriction as from e.g. tenseness or inhibition; "the clarity and resonance of an open tone"; "her natural and open response"
a clear or unobstructed space or expanse of land or water; "finally broke out of the forest into the open" (同)clear
information that has become public; "all the reports were out in the open"; "the facts had been brought to the surface" (同)surface
a tournament in which both professionals and amateurs may play
become available; "an opportunity opened up" (同)open_up
become open; "The door opened" (同)open_up
cause to open or to become open; "Mary opened the car door" (同)open_up
make available; "This opens up new possibilities" (同)open_up
start to operate or function or cause to start operating or functioning; "open a business" (同)open_up
not sealed or having been unsealed; "the letter was already open"; "the opened package lay on the table" (同)opened
used of mouth or eyes; "keep your eyes open"; "his mouth slightly opened" (同)opened
not brought to a conclusion; subject to further thought; "an open question"; "our position on this bill is still undecided"; "our lawsuit is still undetermined" (同)undecided, undetermined, unresolved
affording unobstructed entrance and exit; not shut or closed; "an open door"; "they left the door open" (同)unfastened
(set theory) of an interval that contains neither of its endpoints
accessible to all; "open season"; "an open economy"
affording free passage or access; "open drains"; "the road is open to traffic"; "open ranks"
begin or set in action, of meetings, speeches, recitals, etc.; "He opened the meeting with a long speech"
display the contents of a file or start an application as on a computer
have an opening or passage or outlet; "The bedrooms open into the hall"
having no protecting cover or enclosure; "an open boat"; "an open fire"; "open sports cars"
make the opening move; "Kasparov opened with a standard opening"
not having been filled; "the job is still open"
not requiring union membership; "an open shop employs nonunion workers"
open to or in view of all; "an open protest"; "an open letter to the editor"
ready for business; "the stores are open"
first or beginning; "the memorable opening bars of Beethovens Fifth"; "the plays opening scene"
opportunity especially for employment or promotion; "there is an opening in the sales department"
a recognized sequence of moves at the beginning of a game of chess; "he memorized all the important chess openings" (同)chess opening
a vacant or unobstructed space that is man-made; "they left a small opening for the cat at the bottom of the door"
becoming open or being made open; "the opening of his arms was the sign I was waiting for"
the act of opening something; "the ray of light revealed his cautious opening of the door"
an open or empty space in or between things; "there was a small opening between the trees"; "the explosion made a gap in the wall" (同)gap
the first performance (as of a theatrical production); "the opening received good critical reviews" (同)opening_night, curtain raising
a ceremony accompanying the start of some enterprise
the initial part of the introduction; "the opening established the basic theme"
move or proceed at an angle; "he angled his way into the room"
the space between two lines or planes that intersect; the inclination of one line to another; measured in degrees or radians
fish with a hook
being long-lasting and recurrent or characterized by long suffering; "chronic indigestion"; "a chronic shortage of funds"; "a chronic invalid"
of long duration; "chronic money problems" (同)continuing
habitual; "a chronic smoker" (同)inveterate
an eye disease that damages the optic nerve and impairs vision (sometimes progressing to blindness); "contrary to popular belief, glaucoma is not always caused by elevated intraocular pressure"

PrepTutorEJDIC

…‘を'『開く』,開ける;…‘の'ふた(おおい)をとる / …‘を'『切り開いて作る』,開拓する;…‘を'全開通させる《+『名』+『up,』+『名』+『up』》 / …‘を'『広げる』《+『up』+(『out』)+『名,』+『名』+『up』(『out』)》 / …‘を'『始める』 / …‘を'開業する,開店する,開場する / (人に)〈心など〉‘を'打ち明ける,〈秘密など〉‘を'漏らす《+『名』+『to』+『名』》 / (新思想などに)〈心・目〉‘を'開く《+『名』+『to』+『名』》 / 〈戸などが〉『開く』,あく / 〈花・つぼみが〉開く《+『out』》 / 〈学校などが〉『始まる』;〈店などが〉開く / 〈道路などが〉開通する / (…に)向かって開いている,(…に)通じている《+『out』『on』(『upon,to,onto』)+『名』》 / 《副詞[句]を伴って》〈風景などが〉広がる,ひらける / 本を開く;(…)ページを開く《+『to』(《英》『at』)+『名』》 / (窓・口などが)『開いた』,開いている;(包みなどが)広げられて / (花が)咲いた / (店などが)『開いている』,開業している;(催し物が)『公開の』,だれでも入れる / 《名詞の前にのみ用いて》ふたのしてない,屋根のない,おおいのない / 広く開いた,さえぎるものがない / 公然の / 率直な,遠慮しない / さらされている,無防備の / 《補語にのみ用いて》(職・地位などが)空位の;(時間などが)あいている / (問題・議事などが)未解決の / 凍結しない,雪や霜の降らない;温和な / (漁・猟が)解禁の / (音声が)開口音の;開音節の / 《the~》戸外,野外 / 空き地;(樹木のない)開けた場所,平野
〈C〉(森・垣根・壁などの)空いている所;空き地;すき間,穴 / 〈C〉(物語・会議などの)始め,出だし,冒頭(beginning) / 〈C〉(…の地位の)空き,就職口《+『for』(『at, in』)+『名』》(vacant) / 〈C〉(劇などの)初演 / 〈U〉(…が)開くこと,あくこと《+『of』+『名』》 / 〈C〉(…の)よい機会,好機《+『for』+『名』》 / 初めの,開始の
『かど』,すみ(corner) / 『角』,角度 / 《話》(ものを見る)角度,観点(point of view) / …'を'ある角度に動かす(向ける,曲げる) / …'を'ある角度から見る
(楽しみとして)魚釣りをする;(魚を)釣る《+『for』+『名』》
(病気が)長期にわたる,慢性の / 《名詞の前にのみ用いて》常習の,癖になった
あおそこひ,緑内障(視力が減退する眼病)

UpToDate Contents

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1. 開放隅角緑内障：疫学、臨床症状、および診断 open angle glaucoma epidemiology clinical presentation and diagnosis
2. 閉塞隅角緑内障 angle closure glaucoma
3. 幼児および小児における緑内障の概要 overview of glaucoma in infants and children
4. 眼の待機手術に対する麻酔 anesthesia for elective eye surgery
5. 開放隅角緑内障：治療 open angle glaucoma treatment

English Journal

Pattern of peripapillary capillary density loss in ischemic optic neuropathy compared to that in primary open-angle glaucoma.

Fard MA1, Suwan Y2,3, Moghimi S1, Geyman LS4, Chui TY3, Rosen RB3, Ritch R3.
PloS one.PLoS One.2018 Jan 10;13(1):e0189237. doi: 10.1371/journal.pone.0189237. eCollection 2018.
PMID 29320503

Case Report: Xen ab Interno Gel Stent Use in a Refractory Glaucoma Patient with Previous Filtration Surgeries.

Sandhu S1, Dorey MW.
Journal of glaucoma.J Glaucoma.2018 Jan 4. doi: 10.1097/IJG.0000000000000864. [Epub ahead of print]
PMID 29303873

Increased intraocular pressure alters the cellular distribution of HuR protein in retinal ganglion cells - A possible sign of endogenous neuroprotection failure.

Smedowski A1, Liu X2, Podracka L3, Akhtar S4, Trzeciecka A5, Pietrucha-Dutczak M6, Lewin-Kowalik J6, Urtti A3, Ruponen M3, Kaarniranta K7, Varjosalo M2, Amadio M8.
Biochimica et biophysica acta.Biochim Biophys Acta.2018 Jan;1864(1):296-306. doi: 10.1016/j.bbadis.2017.10.030. Epub 2017 Oct 28.
PMID 29107807