chondroitinase ABC

• コンドロイチナーゼABC

関

chondroitin ABC lyase

WordNet

1. the 1st letter of the Roman alphabet (同)a
2. the blood group whose red cells carry the A antigen (同)type_A, group A
3. the blood group whose red cells carry both the A and B antigens (同)type_AB, group AB

PrepTutorEJDIC

1. answer / ampere
2. 〈U〉アルファベット / 〈U〉〈C〉《the ~》(物事の)初歩,入門,いろは《+『of』+『名』》

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/11/23 16:16:03」(JST)

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Chondroitin ABC lyase
Identifiers
EC number	4.2.2.4
CAS number	9024-13-9
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Chondroitin ABC lyase (EC 4.2.2.4, chondroitinase, chondroitin ABC eliminase, chondroitinase ABC) is an enzyme with system name chondroitin ABC lyase. This enzyme catalyses the following chemical reaction

Eliminative degradation of polysaccharides containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucuronosyl or 1,3-alpha-L-iduronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups

This enzyme acts on chondroitin 4-sulfate, chondroitin 6-sulfate and dermatan sulfate.

References

External links

• Chondroitin ABC lyase at the US National Library of Medicine Medical Subject Headings (MeSH)

UpToDate Contents

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English Journal

• Improvement of activity and stability of Chondroitinase ABC I by introducing an aromatic cluster at the surface of protein.

• Shahaboddin ME1, Khajeh K2, Maleki M3, Golestani A4.
• Enzyme and microbial technology.Enzyme Microb Technol.2017 Oct;105:38-44. doi: 10.1016/j.enzmictec.2017.06.004. Epub 2017 Jun 15.
• PMID 28756859

• Calcium and TNFα additively affect the chondroitinase ABC I activity.

• Bagherieh M1, Kheirollahi A1, Shahaboddin ME1, Khajeh K2, Golestani A3.
• International journal of biological macromolecules.Int J Biol Macromol.2017 Oct;103:1201-1206. doi: 10.1016/j.ijbiomac.2017.05.177. Epub 2017 Jun 3.
• PMID 28587958

• Neural stem cell mediated recovery is enhanced by Chondroitinase ABC pretreatment in chronic cervical spinal cord injury.

• Suzuki H1,2, Ahuja CS1,3,4, Salewski RP1,3,5, Li L1, Satkunendrarajah K1, Nagoshi N1,6, Shibata S7, Fehlings MG1,3,5,4,8.
• PloS one.PLoS One.2017 Aug 3;12(8):e0182339. doi: 10.1371/journal.pone.0182339. eCollection 2017.
• PMID 28771534

Japanese Journal

• Demonstration of the hepatocyte growth factor signaling pathway in the in vitro neuritogenic activity of chondroitin sulfate from ray fish cartilage

• Hashiguchi Taishi,Kobayashi Takanari,Fongmoon Duriya,Shetty Ajaya Kumar,Mizumoto Shuji,Miyamoto Nobuyuki,Nakamura Toshikazu,Yamada Shuhei,Sugahara Kazuyuki
• Biochimica et Biophysica Acta (BBA) : General Subjects 1810(4), 406-413, 2011-04
• … A disaccharide analysis using chondroitinase ABC revealed that the major unit in the CS preparation was GlcUA-GalNAc(6-O-sulfate) (63%), where GlcUA and GalNAc represent D-glucuronic acid and N-acetyl-D-galactosamine, respectively. … The prepration showed NOP activity in vitro, which was eliminated by digestion with chondroitinase ABC, suggesting that a polymeric structure is required for the activity. …
• NAID 120002934270

• 軸索再生と神経可塑性におけるコンドロイチン硫酸

• Kwok Jessica C.F.,Tan Chin Lik,Wang Difei,Heller Janosch,Fawcett James W.
• Trends in Glycoscience and Glycotechnology 23(133), 201-211, 2011
• … 細菌由来の酵素であるコンドロイチナーゼABCによりCSPGsを除去することで、軸索再生が改善される。 …
• NAID 130001493412

Related Links

• Chondroitinase ABC from Proteus vulgaris BSA free ...

Sigma-Aldrich offers Sigma-C3667, Chondroitinase ABC from Proteus vulgaris for your research needs. Find product specific information including CAS, MSDS, protocols and references. ... Other Notes Contains potassium ...

• Chondroitinase ABC promotes functional recovery after spinal ...

Nature is the international weekly journal of science: a magazine style journal that publishes full-length research papers in all disciplines of science, as well as News and Views, reviews, news, features, commentaries ...

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★リンクテーブル★

リンク元	「コンドロイチナーゼABC」「chondroitin ABC lyase」
関連記事	「chondroitinase」「A」「ABC」「AB」

「コンドロイチナーゼABC」

　　[★]

英

chondroitinase ABC

関

コンドロイチンABCリアーゼ

参考

• 1. - OMIM

http://omim.org/entry/300753

「chondroitin ABC lyase」

　　[★]

コンドロイチンABCリアーゼ

関

chondroitinase ABC

「chondroitinase」

　　[★]

コンドロイチナーゼ、コンドロイチン分解酵素

関

chondroitinase and chondroitin lyase

「A」

　　[★]

• アデニン adenine
• アデノシン adenosine
• アラニン alanine

　 　 　

「ABC」

　　[★]

• ATP binding cassette
• airway, breathing, circulation
• アバカビル abacavir

　

「AB」

　　[★]

同

asthmatic bronchitis, 喘息性気管支炎