WordNet

small room in which a monk or nun lives (同)cubicle
a device that delivers an electric current as the result of a chemical reaction (同)electric cell
a room where a prisoner is kept (同)jail cell, prison cell
(biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals
any small compartment; "the cells of a honeycomb"
a small unit serving as part of or as the nucleus of a larger political movement (同)cadre
occupy an intermediate or middle position or form a connecting link or stage between two others; "mediate between the old and the new"
acting through or dependent on an intervening agency; "the disease spread by mediate as well as direct contact"
(medicine) the condition in which an organism can resist disease (同)resistance
the quality of being unaffected by something; "immunity to criticism"
acting or brought about through an intervening agency; "the mediated settlement brought satisfaction to both sides"

PrepTutorEJDIC

(刑務所の)『独房』;(修道院の)小さい独居室 / (ミツバチの)みつ房,巣穴 / 小さい部屋 / 『細胞』 / 電池 / 花粉室 / (共産党などの)細胞
〈紛争・相違点など〉‘を'調停する,仲裁する / 〈妥協・和解・同意など〉‘を'仲裁して成立させる / (両者の)調停をする《+『between』+『名』》 / 仲介者(媒介物)を通じての,間接の
〈U〉(病気に対する)免疫《+『from』(『to, against』)+『名』》 / (義務・税などの)免除《+『from』(『to, against』)+『名』》

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/11/27 21:29:57」(JST)

wiki en

Cell mediated immunity is an immune response that does not involve antibodies, but rather involves the activation of phagocytes, antigen-specific cytotoxic T-lymphocytes, and the release of various cytokines in response to an antigen. Historically, the immune system was separated into two branches: humoral immunity, for which the protective function of immunization could be found in the humor (cell-free bodily fluid or serum) and cellular immunity, for which the protective function of immunization was associated with cells. CD4 cells or helper T cells provide protection against different pathogens. Cytotoxic T cells cause death by apoptosis without using cytokines, therefore in cell-mediated immunity cytokines are not always present.

The innate immune system and the adaptive immune system each comprise both humoral and cell-mediated components.

Cellular immunity protects the body by:

activating antigen-specific cytotoxic T-lymphocytes that are able to induce apoptosis in body cells displaying epitopes of foreign antigen on their surface, such as virus-infected cells, cells with intracellular bacteria, and cancer cells displaying tumor antigens;
activating macrophages and natural killer cells, enabling them to destroy pathogens; and
stimulating cells to secrete a variety of cytokines that influence the function of other cells involved in adaptive immune responses and innate immune responses.

Cell-mediated immunity is directed primarily at microbes that survive in phagocytes and microbes that infect non-phagocytic cells. It is most effective in removing virus-infected cells, but also participates in defending against fungi, protozoans, cancers, and intracellular bacteria. It also plays a major role in transplant rejection.

Template:Hypersensitivity and auto immune diseases

UpToDate Contents

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1. 適応細胞性免疫応答 the adaptive cellular immune response
2. 免疫系の臨床検査評価 laboratory evaluation of the immune system
3. 感染症を繰り返す成人に対するアプローチ approach to the adult with recurrent infections
4. 免疫系におけるサイトカインの役割 role of cytokines in the immune system
5. 抗原提示細胞 antigen presenting cells

English Journal

Insulin-like growth factors inhibit dendritic cell-mediated anti-tumor immunity through regulating ERK1/2 phosphorylation and p38 dephosphorylation.

Huang CT1, Chang MC2, Chen YL3, Chen TC2, Chen CA2, Cheng WF4.
Cancer letters.Cancer Lett.2015 Apr 1;359(1):117-26. doi: 10.1016/j.canlet.2015.01.007. Epub 2015 Jan 12.
Insulin-like growth factors (IGFs) can promote tumorigenesis via inhibiting the apoptosis of cancer cells. The relationship between IGFs and dendritic cell (DC)-mediated immunity were investigated. Advanced-stage ovarian carcinoma patients were first evaluated to show higher IGF-1 and IGF-2 concentr
PMID 25592043

A novel "priming-boosting" strategy for immune interventions in cervical cancer.

Liao S1, Zhang W2, Hu X3, Wang W4, Deng D1, Wang H1, Wang C1, Zhou J1, Wang S1, Zhang H5, Ma D6.
Molecular immunology.Mol Immunol.2015 Apr;64(2):295-305. doi: 10.1016/j.molimm.2014.12.007. Epub 2015 Jan 6.
Despite the encouraging development of a preventive vaccine for human papillomavirus (HPV), it cannot improve ongoing infections. Therefore, a new vaccine is urgently needed that can prevent and treat cervical cancer, and cure pre-cancerous lesions. In this study, we constructed two peptide-based va
PMID 25575128

Intranasal immunization with fusion protein MrpH·FimH and MPL adjuvant confers protection against urinary tract infections caused by uropathogenic Escherichia coli and Proteus mirabilis.

Habibi M1, Asadi Karam MR1, Shokrgozar MA2, Oloomi M1, Jafari A1, Bouzari S3.
Molecular immunology.Mol Immunol.2015 Apr;64(2):285-94. doi: 10.1016/j.molimm.2014.12.008. Epub 2015 Jan 4.
Urinary tract infections (UTIs) caused by Uropathogenic Escherichia coli (UPEC) and Proteus mirabilis are among the most common infections in the world. Currently there are no vaccines available to confer protection against UTI in humans. In this study, the immune responses and protection of FimH of
PMID 25562574

Japanese Journal

Adaptive immune response to Edwardsiella tarda infection in ginbuna crucian carp, Carassius auratus langsdorfii

YAMASAKI Masatoshi,ARAKI Kyosuke,NAKANISHI Teruyuki,NAKAYASU Chihaya,YOSHIURA Yasutoshi,IIDA Takaji,YAMAMOTO Atsushi,ヤマサキマサトシ,アラキキョウスケ,ナカニシテルユキ,ナカヤスチハヤ,ヨシウラヤストシ,イイダタカジ,ヤマモトアツシ,山﨑雅俊,荒木亨介,中西照幸,中易千早,吉浦康壽,飯田貴次,山本淳
Veterinary Immunology and Immunopathology 153(1-2), 83-90, 2013-05-15
… Although cell-mediated immunity and innate immunity play a major role in protection against intracellular bacterial infection in mammals, their importance in protecting fish against E. … In this study, we examined cell-mediated and humoral immune responses in ginbuna crucian carp (Carassius auratus langsdorfii) after E. …
NAID 120005303791

Expression profiles of interferon gamma genes in response to immunostimulants and alloantigen in ginbuna crucian carp Carassius auratus langsdorfii

Araki Kyosuke,Takizawa Fumio,Yamasaki Masatoshi [他]
Fisheries science 79(2), 213-220, 2013-03
NAID 40019634235

Comparison of Cell-Mediated Immunity Induced by Three Commercial Single-Dose Mycoplasma hyopneumoniae Bacterins in Pigs

SEO Hwi Won,HAN Kiwon,OH Yeonsu [他]
The journal of veterinary medical science 75(2), 245-247, 2013-02
NAID 40019597256

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★リンクテーブル★

リンク元	「細胞性免疫」「CMI」「cell immunity」「細胞媒介性免疫反応」「細胞媒介免疫」
拡張検索	「T-cell-mediated immunity」
関連記事	「mediate」「cell」