WordNet

a salt of phosphoric acid (同)orthophosphate, inorganic_phosphate
carbonated drink with fruit syrup and a little phosphoric acid
beta blocker that can reduce the progression of heart failure in individuals whose disease is not advanced

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Beneficial effects of beta-blockers on left ventricular function and cellular energy reserve in patients with heart failure.

Spoladore R, Fragasso G, Perseghin G, De Cobelli F, Esposito A, Maranta F, Calori G, Locatelli M, Lattuada G, Scifo P, Del Maschio A, Margonato A.SourceClinical Cardiology - Heart Failure Clinic, Istituto Scientifico-Università Vita/Salute San Raffaele, Via Olgettina 60, 20132 Milano, Italy. spoladore.roberto@hsr.it
Fundamental & clinical pharmacology.Fundam Clin Pharmacol.2013 Aug;27(4):455-64. doi: 10.1111/j.1472-8206.2012.01029.x. Epub 2012 Feb 9.
Beta-blockers have been shown to improve left ventricular (LV) function in patients with heart failure. The aim of this study is to non-invasively assess, by means of in vivo 31P-magnetic resonance spectroscopy (31P-MRS), the effects of beta-blockers on LV cardiac phosphocreatine and adenosine triph
PMID 22320703

Effect of chronic hypoxic hypoxia on oxidation and glucuronidation of carvedilol in rats.

Yamaura S, Fukao M, Ishida K, Taguchi M, Hashimoto Y.SourceGraduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama, 930-0194, Japan.
European journal of drug metabolism and pharmacokinetics.Eur J Drug Metab Pharmacokinet.2013 Jun 6. [Epub ahead of print]
Heart failure is accompanied with tissue (circulatory) hypoxia, and the metabolism of several drugs has been reported to be reduced in heart failure. The aim of this study was to investigate the effect of another type of respiratory hypoxia, hypoxic hypoxia (FiO2 15 % for 24 h followed by FiO2 10�
PMID 23739952

Carvedilol treatment after myocardial infarct decreases cardiomyocytic apoptosis in the peri-infarct zone during cardioplegia-induced cardiac arrest.

Yeh CH, Chen TP, Wang YC, Lin YM, Fang SW.SourceDivision of Thoracic & Cardiovascular Surgery, Chang Gung Memorial Hospital at Keelung, Keelung, Taiwan, Republic of China. yehccl@cgmh.org.tw
Shock (Augusta, Ga.).Shock.2013 Apr;39(4):343-52. doi: 10.1097/SHK.0b013e31828c588a.
OBJECTIVE: In this study, experiments were designed to determine which parts and how carvedilol provided protection of the failed hearts under cardioplegia-induced hypoxia/reperfusion (H/R) insult.BACKGROUND: Carvedilol could improve the perioperative and postoperative prognosis of the heart failure
PMID 23481492

Hase Hiroki
Journal of Arrhythmia 27(Supplement), JAC2_1, 2011
… The use of carvedilol or telmisartan reduced morbidity and mortality in dialysis patients with dilated cardiomyopathy. … Moreover, the use of high dose of warfarin accelerate the potetial risk of metastatic calcification in HD patients with elevated serum Ca and phosphate. …
NAID 130002129841

Inhibitory and Stimulative Effects of Amiodarone on Metabolism of Carvedilol in Human Liver Microsomes

Horiuchi Isao,Kato Yuya,Nakamura Arisa [他],Ishida Kazuya,Taguchi Masato,Hashimoto Yukiya
Biological and Pharmaceutical Bulletin 33(4), 717-720, 2010
… It was reported that coadministration of amiodarone with carvedilol increased the serum concentration to dose (C/D) ratio of S-carvedilol in patients with heart failure, but not of R-carvedilol. … The aim of the present study was to investigate the effect of amiodarone and its metabolite on the metabolism of R- and S-carvedilol in human liver microsomes (HLM). …
NAID 130000248026