WordNet

an inactive substance that is a vehicle for a radioactive tracer of the same substance and that assists in its recovery after some chemical reaction
(genetics) an organism that possesses a recessive gene whose effect is masked by a dominant allele; the associated trait is not apparent but can be passed on to offspring
a rack attached to a vehicle; for carrying luggage or skis or the like
a self-propelled wheeled vehicle designed specifically to carry something; "refrigerated carriers have revolutionized the grocery business"
someone whose employment involves carrying something; "the bonds were transmitted by carrier" (同)bearer, toter
a person or firm in the business of transporting people or goods or messages (同)common_carrier
(medicine) a person (or animal) who has some pathogen to which he is immune but who can pass it on to others (同)immune carrier
a boy who delivers newspapers (同)newsboy
the act of detecting something; catching sight of something (同)catching, espial, spying, spotting
a police investigation to determine the perpetrator; "detection is hard on the feet" (同)detecting, detective work, sleuthing
the perception that something has occurred or some state exists; "early detection can often lead to a cure" (同)sensing

PrepTutorEJDIC

『運搬する人』;輸送業者(会社) / 運搬する物,運客車;運客設備 / (…の)媒介体,保菌者《+『of』+『名』》 / (また『aircraft carrier』)航空母艦 / (自転車・車の)荷台
発見,探知,発覚 / (電波の)検波

UpToDate Contents

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1. Cystic fibrosis: Carrier screening
2. D型肝炎ウイルス感染の診断 diagnosis of hepatitis d virus infection
3. 血友病の臨床症状および診断 clinical manifestations and diagnosis of hemophilia
4. 無ガンマグロブリン血症 agammaglobulinemia
5. ムコ多糖症：臨床的特徴および診断 mucopolysaccharidoses clinical features and diagnosis

English Journal

A novel hapten and monoclonal-based enzyme-linked immunosorbent assay for sulfonamides in edible animal tissues.

Zhou Q1, Peng D1, Wang Y1, Pan Y1, Wan D1, Zhang X1, Yuan Z2.Author information 1National Reference Laboratory of Veterinary Drug Residues (HZAU) and MOA Key Laboratory for the Detection of Veterinary Drug Residues in Foods, Huazhong Agricultural University, Wuhan, Hubei 430070, China.2National Reference Laboratory of Veterinary Drug Residues (HZAU) and MOA Key Laboratory for the Detection of Veterinary Drug Residues in Foods, Huazhong Agricultural University, Wuhan, Hubei 430070, China. Electronic address: yuan5802@mail.hzau.edu.cn.AbstractFor high-throughput monitoring of the residues of sulfonamides (SAs) in edible animal tissues, a novel hapten and monoclonal-based indirect competitive enzyme-linked immunosorbent assay (ic-ELISA) was developed. The novel hapten was synthesized and conjugated to carrier protein as immunogen. The spleen cells of the inoculated mice expressing group-specificity against SAs were fused. The obtained monoclonal antibody 4E5 showed the cross-reactivity (CR) to 16 structurally different SAs. Based on this antibody, an optimised icELISA protocol was carried out with only phosphate-buffered saline for the fast extraction of SAs in the tissues. The limits of detection of SAs in chicken ranged from 1.5 to 22.3μgkg(-1). The recoveries were 70.6-121% with less than 24.1% relative standard deviation. The developed ic-ELISA showed a good correlation with high performance liquid chromatography. It would be a useful tool for the screening of residues of SAs in edible animal tissues.
Food chemistry.Food Chem.2014 Jul 1;154:52-62. doi: 10.1016/j.foodchem.2014.01.016. Epub 2014 Jan 14.
For high-throughput monitoring of the residues of sulfonamides (SAs) in edible animal tissues, a novel hapten and monoclonal-based indirect competitive enzyme-linked immunosorbent assay (ic-ELISA) was developed. The novel hapten was synthesized and conjugated to carrier protein as immunogen. The spl
PMID 24518315

Enzyme-free and label-free ultrasensitive electrochemical detection of DNA and adenosine triphosphate by dendritic DNA concatamer-based signal amplification.

Liu S1, Lin Y2, Liu T2, Cheng C2, Wei W2, Wang L3, Li F4.Author information 1College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, People's Republic of China. Electronic address: shufengliu77@yahoo.com.2College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, People's Republic of China.3College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, People's Republic of China. Electronic address: wangli@qust.edu.cn.4College of Chemistry and Pharmaceutical Sciences, Qingdao Agricultural University, Qingdao 266109, People's Republic of China. Electronic address: lifeng@qust.edu.cn.AbstractHybridization chain reaction (HCR) strategy has been well developed for the fabrication of various biosensing platforms for signal amplification. Herein, a novel enzyme-free and label-free ultrasensitive electrochemical DNA biosensing platform for the detection of target DNA and adenosine triphosphate (ATP) was firstly proposed, in which three auxiliary DNA probes were ingeniously designed to construct the dendritic DNA concatamer via HCR strategy and used as hexaammineruthenium(III) chloride (RuHex) carrier for signal amplification. With the developed dendritic DNA concatamer-based signal amplification strategy, the DNA biosensor could achieve an ultrasensitive electrochemical detection of DNA and ATP with a superior detection limit as low as 5aM and 20fM, respectively, and also demonstrate a high selectivity for DNA and ATP detection. The currently proposed dendritic DNA concatamer opens a promising direction to construct ultrasensitive DNA biosensing platform for biomolecular detection in bioanalysis and clinical biomedicine, which offers the distinct advantages of simplicity and cost efficiency owing to no need of any kind of enzyme, chemical modification or labeling.
Biosensors & bioelectronics.Biosens Bioelectron.2014 Jun 15;56:12-8. doi: 10.1016/j.bios.2013.12.066. Epub 2014 Jan 7.
Hybridization chain reaction (HCR) strategy has been well developed for the fabrication of various biosensing platforms for signal amplification. Herein, a novel enzyme-free and label-free ultrasensitive electrochemical DNA biosensing platform for the detection of target DNA and adenosine triphospha
PMID 24445068