WordNet
- of or relating to or characteristic of members of the family Canidae
- any of various fissiped mammals with nonretractile claws and typically long muzzles (同)canid
- one of the four pointed conical teeth (two in each jaw) located between the incisors and the premolars (同)canine_tooth, eyetooth, eye tooth, dogtooth, cuspid
- of or relating to a pointed conical tooth (同)laniary
PrepTutorEJDIC
- 犬の;犬のような / 犬;イヌ科の動物(オオカミ,コヨーテなど) / (また『canine tooth』)犬歯
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/01/12 11:22:35」(JST)
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Canine coronavirus |
|
Canine coronavirus antigen in canine lung tissue |
Virus classification |
Group: |
Group IV ((+)ssRNA) |
Order: |
Nidovirales |
Family: |
Coronaviridae |
Subfamily: |
Coronavirinae |
Genus: |
Alphacoronavirus |
Species: |
Alphacoronavirus 1 |
Subspecies: |
Canine coronavirus |
Canine coronavirus is a virus of the family Coronaviridae that causes a highly contagious intestinal disease worldwide in dogs. It was discovered in 1971 in Germany during an outbreak in sentry dogs.[1]
Contents
- 1 Canine enteric coronavirus
- 1.1 Pathology
- 1.2 Symptoms, diagnosis, treatment, and control
- 2 Canine respiratory coronavirus
- 3 References
Canine enteric coronavirus
Pathology
The virus invades and replicates in the villi of the small intestine. Intestinal disease may be related to virus-induced apoptosis (programmed cell death) of cells of the epithelial mucosa of the small intestine.[2] Canine coronavirus was originally thought to cause serious gastrointestinal disease, but now most cases are considered to be very mild or without symptoms.[3] A more serious complication of canine coronavirus occurs when the dog is also infected with canine parvovirus. Coronavirus infection of the intestinal villi makes the cells more susceptible to parvovirus infection. This causes a much more severe disease than either virus can separately.[4] However, fatal intestinal disease associated with canine coronavirus without the presence of canine parvovirus is still occasionally reported.[5][6] This may be related to the high mutation rate of RNA positive stranded viruses, of which canine coronavirus is one.[1]
Symptoms, diagnosis, treatment, and control
See also: DA2PPC Vaccine
The incubation period is one to three days.[4] The disease is highly contagious and is spread through the feces of infected dogs, who usually shed the virus for six to nine days, but sometimes for six months following infection.[3] Symptoms include diarrhea, vomiting, and anorexia. Diagnosis is through detection of virus particles in the feces. Treatment usually only requires medication for diarrhea, but more severely affected dogs may require intravenous fluids for dehydration. Fatalities are rare. The virus is destroyed by most available disinfectants. There is a vaccine available (ATCvet code: QI07AD11), and it is usually given to puppies, who are more susceptible to canine coronavirus, and to dogs that have a high risk of exposure, such as show dogs.[4]
Canine respiratory coronavirus
Recently, a second type of canine coronavirus (Group II) has been shown to cause respiratory disease in dogs.[7] Known as canine respiratory coronavirus (CRCoV) and found to be similar to strain OC43 of bovine and human coronaviruses, it was first isolated in the United Kingdom in 2003 from lung samples of dogs[8] and has since been found on the European mainland[9] and in Japan.[10] A serological study in 2006 has also shown antibodies to CRCoV to be present in dogs in Canada and the United States.[11] However, a retrospective study in Saskatchewan found that CRCoV may have been present there as far back as 1996.[10]
References
- ^ a b Pratelli A (2006). "Genetic evolution of canine coronavirus and recent advances in prophylaxis". Vet Res 37 (2): 191–200. doi:10.1051/vetres:2005053. PMID 16472519.
- ^ Ruggieri, A; Di Trani, L; Gatto, I; Franco, M; Vignolo, E; Bedini, B; Elia, G; Buonavoglia, C (2007). "Canine coronavirus induces apoptosis in cultured cells". Vet Microbiol 121 (1–2): 64–72. doi:10.1016/j.vetmic.2006.12.016. PMID 17254720.
- ^ a b Pratelli, A. (2005). "Canine Coronavirus Infection". Recent Advances in Canine Infectious Diseases. Retrieved 2006-06-25.
- ^ a b c Ettinger, Stephen J.;Feldman, Edward C. (1995). Textbook of Veterinary Internal Medicine (4th ed.). W.B. Saunders Company. ISBN 0-7216-6795-3.
- ^ Evermann J, Abbott J, Han S (2005). "Canine coronavirus-associated puppy mortality without evidence of concurrent canine parvovirus infection". J Vet Diagn Invest 17 (6): 610–4. PMID 16475526.
- ^ Buonavoglia C, Decaro N, Martella V, Elia G, Campolo M, Desario C, Castagnaro M, Tempesta M (2006). "Canine coronavirus highly pathogenic for dogs". Emerg Infect Dis 12 (3): 492–4. doi:10.3201/eid1205.050839. PMC 3291441. PMID 16704791.
- ^ Ellis, John A. (2006). "Outbreak! How can we approach emerging diseases?" (PDF). Proceedings of the North American Veterinary Conference. Retrieved 2007-01-28.
- ^ Erles K, Toomey C, Brooks H, Brownlie J (2003). "Detection of a group 2 coronavirus in dogs with canine infectious respiratory disease". Virology 310 (2): 216–23. doi:10.1016/S0042-6822(03)00160-0. PMID 12781709.
- ^ Decaro N, Desario C, Elia G, Mari V, Lucente MS, Cordioli P, Colaianni ML, Martella V, Buonavoglia C (2006). "Serological and molecular evidence that canine respiratory coronavirus is circulating in Italy". Vet Microbiol 121 (3–4): 225–30. doi:10.1016/j.vetmic.2006.12.001. PMID 17215093.
- ^ a b Yachi A, Mochizuki M (2006). "Survey of dogs in Japan for group 2 canine coronavirus infection". J Clin Microbiol 44 (7): 2615–8. doi:10.1128/JCM.02397-05. PMC 1489469. PMID 16825396.
- ^ Priestnall S, Brownlie J, Dubovi E, Erles K (2006). "Serological prevalence of canine respiratory coronavirus". Vet Microbiol 115 (1–3): 43–53. doi:10.1016/j.vetmic.2006.02.008. PMID 16551493.
UpToDate Contents
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English Journal
- Full-length genome analysis of canine coronavirus type I.
- Decaro N1, Mari V2, Elia G2, Lanave G2, Dowgier G2, Colaianni ML2, Martella V2, Buonavoglia C2.
- Virus research.Virus Res.2015 Dec 2;210:100-5. doi: 10.1016/j.virusres.2015.07.018. Epub 2015 Jul 26.
- Canine coronavirus types I (CCoV-I) and II (CCoV-II) are usually responsible for mild enteritis in dogs. While the CCoV-II genome has been completely sequenced, to date there are no complete genomic sequence data available publicly for CCoV-I. Thus, the aim of the present study was to analyze the fu
- PMID 26221765
- Prevalence of canine coronavirus (CCoV) in dog in Japan: detection of CCoV RNA and retrospective serological analysis.
- Takano T1, Yamashita S, Murata-Ohkubo M, Satoh K, Doki T, Hohdatsu T.
- The Journal of veterinary medical science / the Japanese Society of Veterinary Science.J Vet Med Sci.2015 Oct 11. [Epub ahead of print]
- We collected rectal swabs from dogs in Japan during 2011 to 2014, and canine coronavirus (CCoV) nucleocapsid gene was detected by RT-PCR. The relationship between CCoV infection and the manifestation of diarrhea symptoms was investigated, and a correlation was noted (df=1, χ2=8.90, P<0.005). The
- PMID 26460314
- Prevalence of canine infectious respiratory pathogens in asymptomatic dogs presented at US animal shelters.
- Lavan R1, Knesl O1,2.
- The Journal of small animal practice.J Small Anim Pract.2015 Sep;56(9):572-6. doi: 10.1111/jsap.12389. Epub 2015 Jul 21.
- OBJECTIVES: To determine the prevalence of nine canine infectious respiratory disease (CIRD) pathogens in asymptomatic dogs presented at animal shelters across the United States.METHODS: Ocular and oronasal swabs from asymptomatic dogs (n = 503) were tested using qPCR assay for Bordetella bronchisep
- PMID 26199194
Japanese Journal
- Prevalence and phylogenetic analysis of canine kobuviruses in diarrhoetic dogs in northeast China
- Prevalence of canine coronavirus (CCoV) in dog in Japan: detection of CCoV RNA and retrospective serological analysis
- Prevalence and phylogenetic analysis of canine kobuviruses in diarrhoetic dogs in northeast China
Related Links
- Canine coronavirus is a virus of the family Coronaviridae that causes a highly contagious intestinal disease worldwide in dogs. It was discovered in 1971 in Germany during an outbreak in sentry dogs.
- WebMD discusses canine coronavirus in dogs including transmission, signs and symptoms, and prevention.
★リンクテーブル★
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- 関
- canine teeth、canine tooth、Canis familiaris、cuspid、dog
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- 関
- Coronaviridae、porcine hemagglutinating encephalomyelitis virus