calcium carbimide

カルバミドカルシウム

関

cyanamide

WordNet

1. a weak soluble dibasic acid (the parent acid of cyanamide salts) (同)cyanamid
2. a white metallic element that burns with a brilliant light; the fifth most abundant element in the earths crust; an important component of most plants and animals (同)Ca, atomic number 20

PrepTutorEJDIC

1. 『カルシウム』(金属元素;化学記号は『Ca』)

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/08/09 23:52:10」(JST)

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Calcium carbimide

Systematic (IUPAC) name
calcium 2-hydroxypropane-1,2,3-tricarboxylate; methylcyanamide
Clinical data
AHFS/Drugs.com	International Drug Names
Identifiers
CAS Number	8013-88-5 Y
ATC code	N07BB02 (WHO)
PubChem	CID 6335910
ChemSpider	21106422 Y
UNII	ZLR270912W N
ChEMBL	CHEMBL2106095 N
Chemical data
Formula	C6H8O7.CH2N2.Ca
Molar mass	288.268 g/mol
SMILES [Ca+2].O=C([O-])CC(O)(CC(=O)O)C([O-])=O.N#CNC
InChI InChI=1S/C6H8O7.C2H4N2.Ca/c7-3(8)1-6(13,5(11)12)2-4(9)10;1-4-2-3;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);4H,1H3;/q;;+2/p-2 Y Key:ZZOBQLACMMNMCT-UHFFFAOYSA-L Y
NY (what is this?)  (verify)

Calcium carbimide, sold as the citrate salt under the trade name Temposil, is an alcohol sensitizing agent. Its effects are similar to the drug disulfiram (Antabuse) in that it interferes with the normal metabolism of alcohol by preventing the breakdown of the metabolic byproduct acetaldehyde. The result is that when alcohol is consumed by users of calcium carbimide, they experience severe reactions which include symptoms such as sweating, difficulty breathing, rapid heartbeat, rash, nausea and vomiting, and headache.

A recent 9-year study found that incorporation of supervised carbimide and the similar drug, disulfiram, into a comprehensive treatment program resulted in an abstinence rate of over 50%.

Temposil was developed by Drs. Ken Ferguson and Gordon Bell, who tested the drug on themselves. It was patented in 1955 by the Alcoholism Research Foundation of Ontario.

See also

• Acamprosate

References

UpToDate Contents

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• 1. 思春期におけるカルシウムの所要量 calcium requirements in adolescents
• 2. 骨粗鬆症におけるカルシウムおよびビタミンDの補充 calcium and vitamin d supplementation in osteoporosis
• 3. カルシウムおよびリン酸バランスの調節 regulation of calcium and phosphate balance
• 4. 副甲状腺ホルモンの分泌および作用 parathyroid hormone secretion and action
• 5. 成人における再発性カルシウム結石の予防 prevention of recurrent calcium stones in adults

English Journal

• Biosynthesis and application of Ag/bone nanocomposite for the hydration of cyanamides in Myrica gale L. extract as a green solvent.

• Momeni SS1, Nasrollahzadeh M2, Rustaiyan A1.
• Journal of colloid and interface science.J Colloid Interface Sci.2017 Aug 1;499:93-101. doi: 10.1016/j.jcis.2017.03.079. Epub 2017 Mar 22.
• PMID 28364719

• Palladium-mediated 11C-carbonylations using aryl halides and cyanamide.

• Nordeman P1, Chow SY2, Odell AF3, Antoni G1, Odell LR2.
• Organic & biomolecular chemistry.Org Biomol Chem.2017 May 24. doi: 10.1039/c7ob01064h. [Epub ahead of print]
• PMID 28537303

• Enhanced base-catalyzed activity and structural stability of nitrogen-doped carbon modified MgO-MgFe2O4 magnetic composites as catalysts for transesterification of tributyrin.

• Zhang Y1, Zhang M, Yang L, Fan G, Li F.
• Dalton transactions (Cambridge, England : 2003).Dalton Trans.2017 May 16;46(19):6324-6332. doi: 10.1039/c7dt00689f.
• PMID 28453008

Japanese Journal

• 新坑酒剤Citrated Calcium Carbimideの臨床経験

• 脳と神経 11(2), ????, 1959-02
• NAID 40018424398

• 新抗酒剤Citrated Calcium Carbimide(Temposil)による禁酒療法

• 脳と神経 10(12), ????, 1958-12
• NAID 40018425095

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★リンクテーブル★

リンク元	「シアナミド」「cyanamide」「カルバミドカルシウム」
関連記事	「calcium」

「シアナミド」

　　[★]

英

cyanamide

化

カルシウムシアナミド calcium cyanamide、カルシウムカルビミド calcium carbimide

商

シアナマイド

関

カルバミドカルシウム

「cyanamide」

　　[★]

シアナミド

関

calcium carbimide

　

「カルバミドカルシウム」

　　[★]

英

calcium carbimide

関

シアナミド

「calcium」

　　[★]

• カルシウム Ca2+