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English Journal
- Drug interaction profile of the HIV integrase inhibitor cabotegravir: assessment from in vitro studies and a clinical investigation with midazolam.
- Reese MJ1, Bowers GD1, Humphreys JE1, Gould EP2, Ford SL2, Webster LO1, Polli JW1.
- Xenobiotica; the fate of foreign compounds in biological systems.Xenobiotica.2016 May;46(5):445-56. doi: 10.3109/00498254.2015.1081993. Epub 2015 Sep 4.
- 1. Cabotegravir (CAB; GSK1265744) is a potent HIV integrase inhibitor in clinical development as an oral lead-in tablet and long-acting injectable for the treatment and prevention of HIV infection. 2. This work investigated if CAB was a substrate for efflux transporters, the potential for CAB to
- PMID 26340566
- Enantiospecific effects of chiral drugs on cytochrome P450 inhibition in vitro.
- Krasulova K1, Siller M1, Holas O2, Dvorak Z3, Anzenbacher P1.
- Xenobiotica; the fate of foreign compounds in biological systems.Xenobiotica.2016 Apr;46(4):315-24. doi: 10.3109/00498254.2015.1076086. Epub 2015 Aug 24.
- 1. The aim of this work was to examine the differences in the inhibitory potency of individual enantiomers and racemic mixtures of selected chiral drugs on human liver microsomal cytochromes P450. 2. The interaction of enantiomeric forms of six drugs (tamsulosin, tolterodine, citalopram, modafin
- PMID 26338061
Japanese Journal
- 2 コンパートメント−肝薬物貯槽−融合型 tube モデルを用いたフルボキサミン併用による薬物間相互作用のシミュレーションと in-vivo 酵素阻害定数の見積もり
- 植物の生長および化学防御に関わるテルペノイド生合成の生物有機化学的研究(奨励賞,受賞業績)
Related Links
- 1. Drug Metab Rev. 2003 Feb;35(1):35-98. Interactions of herbs with cytochrome P450. Zhou S(1), Gao Y, Jiang W, Huang M, Xu A, Paxton JW. Author information: (1)Department of Pharmacy, Faculty of Science, National ...
- Interactions of herbs with cytochrome P450 by Zhou S, Gao Y, Jiang W, Huang M, Xu A, Paxton JW. Department of Pharmacy, Faculty of Science, National University of Singapore, Republic of Singapore. phazsf@nus.edu.sg Drug ...
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