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1. 慢性腎臓疾患に関連する無形成骨症adynamic bone disease associated with chronic kidney disease [show details]
… and bone activity such that calcium load had a significantly greater impact on aortic calcification and stiffness in patients with adynamic bone disease when compared with patients with active bone disease …
2. 骨折のマネージメントの一般原則：骨治癒および骨折についてgeneral principles of fracture management bone healing and fracture description [show details]
…strength, stiffness, and rigidity characteristic of bone. The organic or protein component consists primarily of type I collagen, which lends tensile strength and resiliency. The outer covering of bone, the …
3. 骨粗鬆症の疫学と危険因子epidemiology and risk factors for osteoarthritis [show details]
…predispose the joint to injury. Changes affecting joint tissues include loss of normal bone structure, increased stiffness of ligaments and tendons, and meniscal degeneration. The role of aging in the pathogenesis …
4. 跛行のある小児の評価evaluation of the child with a limp [show details]
… associated symptoms, such as abdominal pain, back pain, joint pain, morning stiffness, recent illness, ataxia, or weakness Bone pain that occurs at night or at rest and without a history of trauma is found …
5. 小児における項部硬直に対するアプローチapproach to neck stiffness in children [show details]
… symptom, often worse at night. Eosinophilic granulomas and bone cysts are rare, benign lesions of the spine that may cause neck pain and/or stiffness. Pneumomediastinum – Spontaneous pneumomediastinum may …

English Journal

How is mechanobiology involved in mesenchymal stem cell differentiation toward the osteoblastic or adipogenic fate?

Benayahu D, Wiesenfeld Y, Sapir-Koren R.
Journal of cellular physiology. 2019 Aug;234(8)12133-12141.
Mechanobiology plays a major role in transducing physical cues from the dynamic cellular environment into biochemical modifications that promote cell-specific differentiation paths. Mesenchymal stem cells in the bone marrow or in other mesenchymal tissues will differentiate according to the expressi
PMID 30633367

A novel 3D printed cage with microporous structure and in vivo fusion function.

Li P, Jiang W, Yan J, Hu K, Han Z, Wang B, Zhao Y, Cui G, Wang Z, Mao K, Wang Y, Cui F.
Journal of biomedical materials research. Part A. 2019 Jul;107(7)1386-1392.
In this study, a novel 3D printed porous titanium cage (3D printed cage) with interconnected pores inside was designed and manufactured. Observations by scanning electron microscopy showed that the inside of the 3D printed cage had an octahedral porous structure, with the pores uniform in size and c
PMID 30724479

Design of a bio-inspired composite using probabilistic fracture mechanics.

Saroj A, Jesna Rose KA, Arun CO, Anup S.
Journal of the mechanical behavior of biomedical materials. 2019 Jul;95()96-102.
Artificial composites inspired from biological materials such as nacre and bone has a staggered structure of hard inclusions surrounded by a soft interface. These composites possess an excellent combination of strength, toughness and stiffness. These properties depends on a critical value of overlap
PMID 30986757

Japanese Journal

動脈硬化

Lee Jun-Hyuk,Lee Ji-Won,Lee Young-Jae
Ｊｏｕｒｎａｌ　ｏｆ　Ａｔｈｅｒｏｓｃｌｅｒｏｓｉｓ　ａｎｄ　Ｔｈｒｏｍｂｏｓｉｓ, 2019
… Serum alkaline phosphatase (ALP), a useful marker of hepatobiliary or bone disorders, has recently been found to be associated with cardiovascular diseases. … This study aimed to examine the association of serum ALP level with arterial stiffness, as measured by brachial-ankle pulse wave velocity.</p><p><b>Methods:</b> …
NAID 130007649720

脳性麻痺者サッカー選手および健常者サッカー選手の踵骨骨強度の左右差の検討

高橋雅足,髙橋康輝,高橋寛
東京有明医療大学雑誌 = Journal of Tokyo Ariake University of Medical and Health Sciences (10), 15-22, 2018-12-31
… GEヘルスケア社A-1000 EXPRESS）を用い，踵骨のStiffness値（％）について検討した．［結果］①脳性麻痺者サッカー選手の踵骨Stiffness値の左右平均値は，22名中14名が100％以上であったが，８名は100％未満であった．特にC7クラスでは，９名中５名が100％未満であった．②脳性麻痺者サッカー選手のＣ5クラスおよびＣ6クラスでは踵骨のStiffness値の左右差に有意差は認められなかった． …
NAID 120006622208

Relationship between bone turnover markers and the heel stiffness index measured by quantitative ultrasound in middle-aged and elderly Japanese men

Nishimura Takayuki,Arima Kazuhiko,Abe Yasuyo,Kanagae Mitsuo,Mizukami Satoshi,Okabe Takuhiro,Tomita Yoshihito,Goto Hisashi,Horiguchi Itsuko,Aoyagi Kiyoshi
Medicine 97(8), e9962, 2018-02
… The aim of the present study was to investigate the age-related patterns and the relationships between serum levels of tartrate-resistant acid phosphatase-5b (TRACP-5b) or bone-specific alkaline phosphatase (BAP), and the heel stiffness index measured by quantitative ultrasound (QUS) in 429 Japanese men, with special emphasis on 2 age groups (40-59 years and 60 years or over). … The heel stiffness index (bone mass) was measured by QUS. …
NAID 120006471122