beta-lipotropin

βリ・トロピン

関

lipotropin

WordNet

1. to remain unmolested, undisturbed, or uninterrupted -- used only in infinitive form; "let her be"
2. work in a specific place, with a specific subject, or in a specific function; "He is a herpetologist"; "She is our resident philosopher" (同)follow
3. have life, be alive; "Our great leader is no more"; "My grandfather lived until the end of war" (同)live
4. be identical to; be someone or something; "The president of the company is John Smith"; "This is my house"
5. happen, occur, take place; "I lost my wallet; this was during the visit to my parents house"; "There were two hundred people at his funeral"; "There was a lot of noise in the kitchen"
6. have the quality of being; (copula, used with an adjective or a predicate noun); "John is rich"; "This is not a good answer"
7. occupy a certain position or area; be somewhere; "Where is my umbrella?" "The toolshed is in the back"; "What is behind this behavior?"
8. spend or use time; "I may be an hour"
9. stake on the outcome of an issue; "I bet $100 on that new horse"; "She played all her money on the dark horse" (同)wager, play
10. the act of gambling; "he did it on a bet" (同)wager
11. maintain with or as if with a bet; "I bet she will be there!" (同)wager
12. second in order of importance; "the candidate, considered a beta male, was perceived to be unable to lead his party to victory"
13. the 2nd letter of the Greek alphabet
14. preliminary or testing stage of a software or hardware product; "a beta version"; "beta software"
15. beets (同)genus Beta

PrepTutorEJDIC

1. 《連結語として補語を伴なって…『である』,…だ,…です / 《位置・場所を表す語句を伴って》(…に)『ある』,いる(occupy a place or situation) / 〈物事が〉『存在する』,ある(exist);〈生物が〉生存する,生きている(live) / 行われる,起こる,発生する(take place, occur) / 存続する,そのままでいる(remain as before) / 《『be to』 do》 / …する予定である,…することになっている / …すべきだ / 《受動態の不定詞を伴って》…できる / 《命令》…するのだ / 《条件節に》…する意図がある / 《『if…were to』 do》…するとしたなら / 《『be』 do『ing』》《進行形》 / 《進行中の動作》…している,しつつある / 《近い未来》…しようとしている,するつもり / 《動作の反復》(いつも)…している / 《『be』+『他動詞の過去分詞』》《受動態》…される,されている / 《『be』+『自動詞の過去分詞』》《完了形》…した[状態にある]
2. 『かけ』・(…との)かけ《+『with』+『名』》 / かけた物(金) / かけの対象 / 〈金・物〉'を'『かける』 / (かけ事・ゲームなどで)〈人〉‘と'『かけをする』《+『名』〈人〉+『on』+『名』》 / (…に)『かける』《+『on』(『against』)+『名』(one's do『ing』)》
3. ベータ(ギリシア語アルファベットの第2文字;B,β;英語のB,b に遭当)

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/07/26 22:46:44」(JST)

wiki en

[Wiki en表示]

pro-opiomelanocortin
Identifiers
Symbol	POMC
Entrez	5443
HUGO	9201
OMIM	176830
RefSeq	NM_000939
UniProt	P01189
Other data
Locus	Chr. 2 p23

Lipotropin is a hormone produced by the cleavage of pro-opiomelanocortin (POMC). The anterior pituitary gland produces the pro-hormone POMC, which is then cleaved again to form adrenocorticotropin (ACTH) and β-lipotropin (β-LPH).

β-Lipotropin

β-Lipotropin is a 90-amino acid polypeptide that is the carboxy-terminal fragment of POMC.

It stimulates melanocytes to produce melanin, and can also be cleaved into smaller peptides. In humans, γ-lipotropin, β-MSH, and β-endorphin, are all possible fragments of β-lipotropin.

β-Lipotropin also performs lipid-mobilizing functions such as lipolysis and steroidogenesis. β-Lipotropin is the predominant opioid of the anterior human and rat pituitary gland. It is found in essentially equimolar concentrations to that of corticotropin. Evidence shows that β-Lipotropin is metabolized into endorphins that can greatly affect mood and behavior and is thus regarded as a prohormone.

γ-Lipotropin

γ-lipotropin is the amino-terminal peptide fragment of β-lipotropin. In humans, it has 56 amino acids. Gamma lipotropin is identical to the first 56 amino acid sequences of β-lipotropin. It can be cleaved to β-melanocyte stimulating hormone.

Use in sport

Lipotropin has also, under its alternate name AOD-9604 (Anti-Obesity Drug-9604), been connected with controversies in Australian Rules Football. Allegations have arisen around the use of the drug and its administration to players of the Essendon Football Club as a supplement, including weekly administration to players in the 2012 season. The matters are currently under investigation due to the relationship between Lipotropin and growth hormones, as noted by club medical staff.

References

External links

• beta-Lipotropin at the US National Library of Medicine Medical Subject Headings (MeSH)
• gamma-Lipotropin at the US National Library of Medicine Medical Subject Headings (MeSH)

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

• 1. ACTH、CRH、および他の視床下部／下垂体ペプチドの測定 measurement of acth crh and other hypothalamic and pituitary peptides

English Journal

• 60 YEARS OF POMC: POMC: the consummate peptide hormone precursor.

• Clark AJ1, Lowry P2.
• Journal of molecular endocrinology.J Mol Endocrinol.2016 May;56(4):E1-2. doi: 10.1530/JME-16-0016.
• PMID 27273100

• 60 YEARS OF POMC: Lipotropin and beta-endorphin: a perspective.

• Smyth DG1.
• Journal of molecular endocrinology.J Mol Endocrinol.2016 May;56(4):T13-25. doi: 10.1530/JME-16-0033. Epub 2016 Feb 22.
• PMID 26903509

• 60 YEARS OF POMC: Biosynthesis, trafficking, and secretion of pro-opiomelanocortin-derived peptides.

• Cawley NX1, Li Z1, Loh YP2.
• Journal of molecular endocrinology.J Mol Endocrinol.2016 May;56(4):T77-97. doi: 10.1530/JME-15-0323. Epub 2016 Feb 15.
• PMID 26880796

Related Pictures

---

★リンクテーブル★

リンク元	「βリポトロピン」
関連記事	「beta」「be」

「βリポトロピン」

　　[★]

英

beta-lipotropin, β-LPH

関

リポトロピン、

• 下垂体前葉ではプロオピオメラノコルチン(POMC)からACTHとβ-LPHが合成される。

「beta」

　　[★]

β、ベータ 　 　 　 　

「be」

　　[★]