WordNet
- (biochemistry) a drug that can combine with a receptor on a cell to produce a physiological reaction
- a muscle that contracts while another relaxes; "when bending the elbow the biceps are the agonist"
- someone involved in a contest or battle (as in an agon)
- a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response
- any of several similar lipophilic amines used as tranquilizers or sedatives or hypnotics or muscle relaxants; chronic use can lead to dependency
PrepTutorEJDIC
- =sense organ / 受信装置
UpToDate Contents
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English Journal
- Menthol enhances phasic and tonic GABAA receptor-mediated currents in midbrain periaqueductal grey neurons.
- Lau BK1, Karim S, Goodchild AK, Vaughan CW, Drew GM.
- British journal of pharmacology.Br J Pharmacol.2014 Jun;171(11):2803-13. doi: 10.1111/bph.12602.
- BACKGROUND AND PURPOSE: Menthol, a naturally occurring compound in the essential oil of mint leaves, is used for its medicinal, sensory and fragrant properties. Menthol acts via transient receptor potential (TRPM8 and TRPA1) channels and as a positive allosteric modulator of recombinant GABAA recept
- PMID 24460753
- Muscarinic Receptor Activation Increases hERG Channel Expression through Phosphorylation of Ubiquitin Ligase Nedd4-2.
- Wang T1, Hogan-Cann A, Kang Y, Cui Z, Guo J, Yang T, Lamothe SM, Li W, Ma A, Fisher JT, Zhang S.
- Molecular pharmacology.Mol Pharmacol.2014 Jun;85(6):877-86. doi: 10.1124/mol.113.091553. Epub 2014 Mar 31.
- The human ether-à-go-go-related gene (hERG) encodes the pore-forming subunit of the rapidly activating delayed rectifier potassium channel, which is important for cardiac repolarization. Reduction of hERG current due to genetic mutations or drug interferences causes long QT syndrome, leading to car
- PMID 24688054
Japanese Journal
- Effects of the 5-HT1A Receptor Agonist Tandospirone on ACTH-Induced Sleep Disturbance in Rats
- Tsutsui Ryuki,Shinomiya Kazuaki,Sendo Toshiaki,Kitamura Yoshihisa,Kamei Chiaki
- Biological and Pharmaceutical Bulletin 38(6), 884-888, 2015
- … The aim of this study was to compare the effect of the serotonin (5-HT)1A receptor agonist tandospirone versus that of the benzodiazepine hypnotic flunitrazepam in a rat model of long-term adrenocorticotropic hormone (ACTH)-induced sleep disturbance. … The effect of tandospirone on sleep patterns was antagonized by the 5-HT1A receptor antagonist WAY-100635. …
- NAID 130005072657
- 松田 博史
- てんかん研究 = Journal of the Japan Epilepsy Society 31(1), 57-60, 2013-06-30
- てんかんの核医学診断には、脳血流SPECTおよび外科的治療が考慮される部分てんかん患者に対する18F-FDG PETと123I-iomazenil SPECTによるてんかん焦点の検出が挙げられる。18F-FDG PETは発作間欠期に行い、焦点およびその周囲の代謝低下を検出する。側頭葉てんかんでは高い診断能を有するが、側頭葉外てんかんでは診断能は低下する。123I-iomazenil SPECTは焦 …
- NAID 10031178430
Related Links
- Minor tranquilizers slow down central nervous system. ... Sleep Medications: Benzodiazepines Benzodiazepines receptor agonists (BzRAs) are a group of prescription drugs that slow down the body’s central nervous system ...
- 1. J Pharmacol Sci. 2009 May;110(1):36-46. Comparison of five benzodiazepine-receptor agonists on buprenorphine-induced mu-opioid receptor regulation. Poisnel G(1), Dhilly M, Le Boisselier R, Barre L, Debruyne D. ...
Related Pictures
★リンクテーブル★
[★]
- 関
- agonist、agonistic
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- 関
- GABA-A receptor
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ベンゾジアゼピン系薬物
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ベンゾジアゼピン系薬物