- 関
- benserazide
WordNet
- a complex consisting of an organic base in association with hydrogen chloride
UpToDate Contents
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English Journal
- Effects of prolonged selective serotonin reuptake inhibition on the development and expression of L-DOPA-induced dyskinesia in hemi-parkinsonian rats.
- Conti MM1, Ostock CY2, Lindenbach D3, Goldenberg AA4, Kampton E5, Dell'isola R6, Katzman AC7, Bishop C8.
- Neuropharmacology.Neuropharmacology.2014 Feb;77:1-8. doi: 10.1016/j.neuropharm.2013.09.017. Epub 2013 Sep 22.
- Dopamine (DA) replacement therapy with l-DOPA is the standard treatment for Parkinson's disease (PD). Unfortunately chronic treatment often leads to the development of abnormal involuntary movements (AIMs) referred to as L-DOPA-induced dyskinesia (LID). Accumulating evidence has shown that compensat
- PMID 24067924
- Dopamine receptor activation increases glial cell line-derived neurotrophic factor in experimental stroke.
- Kuric E1, Wieloch T, Ruscher K.
- Experimental neurology.Exp Neurol.2013 Sep;247:202-8. doi: 10.1016/j.expneurol.2013.04.016. Epub 2013 May 9.
- Treatment with levodopa enhances functional recovery after experimental stroke but its mechanisms of action are elusive. Reactive astrocytes in the ischemic hemisphere are involved in mechanisms promoting recovery and also express dopamine 1 (D1) and dopamine 2 (D2) receptors. Here we investigated i
- PMID 23664961
- Exercise attenuates levodopa-induced dyskinesia in 6-hydroxydopamine-lesioned mice.
- Aguiar AS Jr1, Moreira EL, Hoeller AA, Oliveira PA, Córdova FM, Glaser V, Walz R, Cunha RA, Leal RB, Latini A, Prediger RD.
- Neuroscience.Neuroscience.2013 Jul 23;243:46-53. doi: 10.1016/j.neuroscience.2013.03.039. Epub 2013 Apr 1.
- L-DOPA alleviates the motor symptoms of Parkinson's disease, but its long-term use is associated with undesirable dyskinesia. We now tested whether exercise can attenuate this L-DOPA-induced dyskinesia (LID). We tested the effects of exercise on LID in 6-hydroxydopamine hydrochloride-hemiparkinsonia
- PMID 23558088
Related Links
- Sigma-Aldrich offers Sigma-B7283, Benserazide hydrochloride for your research needs. Find product specific information including CAS, MSDS, protocols and references. ... Biochem/physiol Actions Inhibitor of L-aromatic amino acid ...
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★リンクテーブル★
[★]
- 英
- benserazide、benserazide hydrochloride
- 関
- 塩酸ベンセラジド。ネオドパゾール配合
- レボドパ脱炭酸酵素阻害薬であり、脳以外の末梢各組織でレボドパの脱炭酸反応を防ぐ。レボドパに配合することで、末梢での血中レボドパ濃度が高め、脳内へのレボドパ移行量を増加させる。
[★]
- 英
- benserazide hydrochloride
- 関
- ベンセラジド
[★]
塩酸塩、ハイドロクロライド