WordNet

not arising from natural growth or characterized by vital processes
artificially formal; "that artificial humility that her husband hated"; "contrived coyness"; "a stilted letter of acknowledgment"; "when people try to correct their speech they develop a stilted pronunciation" (同)contrived, hokey, stilted
contrived by art rather than nature; "artificial flowers"; "artificial flavoring"; "an artificial diamond"; "artificial fibers"; "artificial sweeteners" (同)unreal

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1. サーファクタント機能障害の遺伝性疾患 genetic disorders of surfactant dysfunction
2. 急性呼吸窮迫症候群：新しい治療法 acute respiratory distress syndrome novel therapies in adults
3. 気管支肺異形成症の病因および臨床的特徴 pathogenesis and clinical features of bronchopulmonary dysplasia
4. 小児における肺胞蛋白症 pulmonary alveolar proteinosis in children
5. 初期肺移植片機能不全 primary lung graft dysfunction

Hydrophobic ion pairing of a minocycline/Ca(2+)/AOT complex for preparation of drug-loaded PLGA nanoparticles with improved sustained release.

Holmkvist AD1, Friberg A2, Nilsson UJ3, Schouenborg J2.
International journal of pharmaceutics.Int J Pharm.2016 Feb 29;499(1-2):351-7. doi: 10.1016/j.ijpharm.2016.01.011. Epub 2016 Jan 7.
Polymeric nanoparticles is an established and efficient means to achieve controlled release of drugs. Incorporation of minocycline, an antibiotic with anti-inflammatory and neuroprotective properties, into biodegradable nanoparticles may therefore provide an efficient means to combat foreign body re
PMID 26773599

Interaction Study and Reactivity of ZrIV -Substituted Wells-Dawson Polyoxometalate towards Hydrolysis of Peptide Bonds in Surfactant Solutions.

Quanten T1, Shestakova P2, Van Den Bulck D1, Kirschhock C3, Parac-Vogt TN4.
Chemistry (Weinheim an der Bergstrasse, Germany).Chemistry.2016 Feb 2. doi: 10.1002/chem.201503976. [Epub ahead of print]
The interaction between the 1:2 ZrIV :Wells-Dawson complex, K15 H[Zr(α2 -P2 W17 O61 )2 ] (1), and a range of surfactants was studied in detail with the aim of developing metal-substituted POMs as potential artificial proteases for membrane proteins. The surfactants include the positively charged ce
PMID 26833582

Evaluation of critical formulation parameters in design and differentiation of self-microemulsifying drug delivery systems (SMEDDSs) for oral delivery of aciclovir.

Janković J1, Djekic L2, Dobričić V3, Primorac M4.
International journal of pharmaceutics.Int J Pharm.2016 Jan 30;497(1-2):301-11. doi: 10.1016/j.ijpharm.2015.11.011. Epub 2015 Dec 1.
The study investigated the influence of formulation parameters for design of self-microemulsifying drug delivery systems (SMEDDSs) comprising oil (medium chain triglycerides) (10%), surfactant (Labrasol(®), polysorbate 20, or Kolliphor(®) RH40), cosurfactant (Plurol(®) Oleique CC 497) (q.s. ad 10
PMID 26611669

Interfacial Behavior of Pulmonary Surfactant Preparations Containing Egg Yolk Lecithin

Nakahara Hiromichi,Shibata Osamu
Journal of Oleo Science 63(11), 1159-1168, 2014
… In this work, which aimed towards the less expensive production of artificial pulmonary surfactants, we produced surfactants composed of egg yolk lecithin (eggPC), palmitic acid, and hexadecanol (= 0.30/0.35/0.35, mol/mol/mol ) containing different amounts of Hel 13-5 (NH2-KLLKLLLKLWLKLLKLLL-COOH) as a substitute for the proteins in native pulmonary surfactants. …
NAID 130004693946

中原広道
薬学雑誌. 乙号 132(7), 817-822, 2012
… Lung surfactants (LS), a complex of ∼90 wt% lipids (mainly dipalmitoylphosphatidylcholine or DPPC) and ∼10 wt% surfactant proteins (SP-A, -B, -C, and -D), adsorb to an air-alveolar fluid interface and then lower its surface tension down to near zero during expiration. … Intratracheal instillation of exogenous LS preparations can effectively compensate for surfactant deficiency in premature infants with respiratory distress syndrome (RDS). …
NAID 130001888695