アドステロール
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2012/11/07 22:30:50」(JST)
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Adosterol |
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IUPAC name
(3S,6S,8S,9S,13R,14S,17R)-6-(iodomethyl)-
13-methyl-17-(6-methylheptan-2-yl)-1,2,3,4,
6,7,8,9,11,12,14,15,16,17-tetradecahydro
cyclopenta[a]phenanthren-3-ol
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Identifiers |
CAS number |
55623-03-5 |
PubChem |
41491 |
ChemSpider |
37858 Y |
MeSH |
Adosterol |
Jmol-3D images |
Image 1
Image 2 |
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CC(C)CCCC(C)[C@H]1CC[C@H]2[C@@H]3C[C@@H]
(CI)C4=C(CC[C@H](O)C4)[C@H]3CC[C@]12C
IC[C@H]2\C4=C(/[C@H]1CC[C@]3([C@H]([C@@H]1C2)CC[C@@H]3C(C)CCCC(C)C)C)CC[C@H](O)C4
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InChI=1S/C27H45IO/c1-17(2)6-5-7-18(3)25-10-11-26-24-14-19(16-28)23-15-20(29)8-9-21(23)22(24)12-13-27(25,26)4/h17-20,22,24-26,29H,5-16H2,1-4H3/t18?,19-,20-,22+,24+,25+,26-,27+/m0/s1 Y
Key: QJHZPCLORSPENH-WJXGYAGSSA-N Y
InChI=1/C27H45IO/c1-17(2)6-5-7-18(3)25-10-11-26-24-14-19(16-28)23-15-20(29)8-9-21(23)22(24)12-13-27(25,26)4/h17-20,22,24-26,29H,5-16H2,1-4H3/t18?,19-,20-,22+,24+,25+,26-,27+/m0/s1
Key: QJHZPCLORSPENH-WJXGYAGSBZ
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Properties |
Molecular formula |
C27H45IO |
Molar mass |
512.55 g/mol |
Y (verify) (what is: Y/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
Infobox references |
Adosterol is an iodine-containing sterol.
Cholestanes, membrane lipids: sterols
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- Adosterol
- Cholecalciferol/Ergocalciferols
- Cholesterol
- Dihydrotachysterol
- Fusidic acid
- Lanosterol
- Phytosterols
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English Journal
- Extraordinarily high aldosterone, 901.0 ng/dL, in a patient with primary aldosteronism: an insight into the underlying mechanism.
- Okubo Y1, Sato Y, Nakasone Y, Shirotori K, Oguchi K, Matsushita T, Nishikawa T, Yamazaki Y, Sasano H, Komatsu M, Yamauchi K, Aizawa T.
- Endocrine journal.Endocr J.2016 Feb 29;63(2):127-33. doi: 10.1507/endocrj.EJ15-0398. Epub 2015 Nov 7.
- A 43-yr-old hypertensive male was admitted due to hypokalemia (1.8 mEq/L) and renal dysfunction (eGFR, 20.0 mL/min/1.73 m(2)). His plasma aldosterone was 901.0 ng/dL, plasma renin activity 5.7 ng/mL/hr, and aldosterone/renin activity ratio 158. Angiotensin II (AII) was 0.7 pg/mL, ACTH <1.0 pg/mL,
- PMID 26549209
- Hormonal, Radiological, NP-59 Scintigraphy, and Pathological Correlations in Patients With Cushing's Syndrome Due to Primary Pigmented Nodular Adrenocortical Disease (PPNAD).
- Vezzosi D1, Tenenbaum F1, Cazabat L1, Tissier F1, Bienvenu M1, Carrasco CA1, Laloi-Michelin M1, Barrande G1, Lefebvre H1, Hiéronimus S1, Tabarin A1, Bertagna X1, Legmann P1, Vantyghem MC1, Bertherat J1.
- The Journal of clinical endocrinology and metabolism.J Clin Endocrinol Metab.2015 Nov;100(11):4332-8. doi: 10.1210/jc.2015-2174. Epub 2015 Sep 21.
- CONTEXT: Primary pigmented nodular adrenocortical disease (PPNAD) is a rare cause of ACTH-independent Cushing's syndrome that may occur in an isolated form or as part of Carney complex. The diagnosis of this disease can be difficult preoperatively because computed tomography (CT) scan can be normal
- PMID 26390100
- [Diagnostic benefits of adrenocortical scintigraphy in hepatic adrenal rest tumor].
- Ishida K1, Horii R, Yamashita T, Arai K, Yamashita T, Kagaya T, Sakai Y, Mizukoshi E, Honda M, Kaneko S.
- Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology.Nihon Shokakibyo Gakkai Zasshi.2014 Oct;111(10):2004-12.
- An 81-year-old female was referred to our hospital for the examination of an S7 liver tumor. The tumor was suspected to be a hepatic adrenal rest tumor (HART) based on ultrasonography, dynamic CT, Gd-EOB-DTPA-enhanced MRI, and CT during abdominal angiography. After various hormonal tests, the tumor
- PMID 25283230
Japanese Journal
- Extraordinarily high aldosterone, 901.0 ng/dL, in a patient with primary aldosteronism: an insight into the underlying mechanism
- 術前管理に苦慮した肺結核併存原発性アルドステロン症の1例
- 副腎皮質シンチグラフィが有用であった肝adrenal rest tumorの1例
Related Links
- 副腎皮質シンチグラム アドステロール131I ヨウ化メチルコレステノール 副腎のイメージングへの試みは、1975年Kojimaらは131I-19-ヨードコレステロールの合成分離過程の際、ある条件下では、化学的により安定で副腎集積性の高い ...
- 144.I-131 Adosterolによる副腎Up take ratioの検討(第34回総会会員研究発表)(体外測定-4)
Related Pictures
★リンクテーブル★
[★]
- 英
- adosterol
- 関
- 131I-アドステロール、131I-アドステロール副腎シンチグラフィ
- 副腎に集積する特徴を有する。
- 放射性核種に置換した131I-アドステロールを用いて、シンチグラムの為に用いられる。