WordNet

a straight line segment whose length is magnitude and whose orientation in space is direction
(genetics) a virus or other agent that is used to deliver DNA to a cell
any agent (person or animal or microorganism) that carries and transmits a disease; "mosquitos are vectors of malaria and yellow fever"; "fleas are vectors of the plague"; "aphids are transmitters of plant diseases"; "when medical scientists talk about vectors they are usually talking about insects" (同)transmitter
a variable quantity that can be resolved into components
any of a group of viruses including those that in humans cause upper respiratory infections or infectious pinkeye

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1. アデノウイルスの病因およびベクター使用 adenovirus pathogenesis and vector applications
2. アデノウイルス感染の疫学および臨床症状 epidemiology and clinical manifestations of adenovirus infection
3. 小児における気管支拡張症の原因 causes of bronchiectasis in children
4. エボラウイルス病の治療および予防 treatment and prevention of ebola virus disease
5. C型肝炎ウイルス感染に対する試験的治療 investigational therapies for hepatitis c virus infection

Development of a platform process for adenovirus purification that removes human set and nucleolin and provides high purity vector for gene delivery.

Riske F, Berard N, Albee K, Pan P, Henderson M, Adams K, Godwin S, Spear S.SourceDepartment of Purification Development, Genzyme a Sanofi Company, Framingham, Massachusetts 01710; telephone: 508-271-3528; fax: 508-271-3452. frank.riske@genzyme.com.
Biotechnology and bioengineering.Biotechnol Bioeng.2013 Mar;110(3):848-56. doi: 10.1002/bit.24742. Epub 2012 Oct 18.
The manufacturing of virus occurs at a modest scale in comparison to many therapeutic proteins mainly because a gene therapy dose is typically only µg of vector. Although modest in scale the generation of high purity virus is challenging due to low viral expression levels and the difficulties in ad
PMID 23042531

The VHL tumor suppressor protein regulates tumorigenicity of U87-derived glioma stem-like cells by inhibiting the JAK/STAT signaling pathway.

Kanno H, Sato H, Yokoyama TA, Yoshizumi T, Yamada S.SourceDepartment of Neurosurgery, Yokohama City University School of Medicine, Yokohama, Japan.
International journal of oncology.Int J Oncol.2013 Mar;42(3):881-6. doi: 10.3892/ijo.2013.1773. Epub 2013 Jan 16.
The signal transducer and activator of transcription 3 (STAT3) factor plays an important role in the tumorigenicity of cancer stem cells. The purpose of this study was to investigate the inhibitory mechanism of this pathway acting through the tumor suppressor von
PMID 23338840

A DEAD-box RNA helicase Ddx54 protein in oligodendrocytes is indispensable for myelination in the central nervous system.

Zhan R, Yamamoto M, Ueki T, Yoshioka N, Tanaka K, Morisaki H, Seiwa C, Yamamoto Y, Kawano H, Tsuruo Y, Watanabe K, Asou H, Aiso S.SourceCenter for Kampo Medicine, Keio University School of Medicine, Tokyo, Japan.
Journal of neuroscience research.J Neurosci Res.2013 Mar;91(3):335-48. doi: 10.1002/jnr.23162. Epub 2012 Dec 14.
We recently reported that a new monoclonal antibody, 4F2, which labels oligodendroglial lineage cells, recognizes a DEAD-box RNA helicase Ddx54 and that Ddx54 binds to myelin basic protein (MBP) in brain and cultured oligodendrocytes. To elucidate the biological function of Ddx54, we generated a rec
PMID 23239230