WordNet

any of various usually poisonous plants of the genus Aconitum having tuberous roots and palmately lobed leaves and blue or white flowers
genus of poisonous plants of temperate regions of northern hemisphere with a vaulted and enlarged petal (同)genus Aconitum
a variety of chert containing magnetite and hematite; mined as a low-grade iron ore
small Old World perennial herb grown for its bright yellow flowers which appear in early spring often before snow is gone (同)Eranthis hyemalis

PrepTutorEJDIC

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/07/07 10:41:33」(JST)

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 小児での潜在的に毒性を持つ植物の摂取による臨床症状および評価 clinical manifestations and evaluation of potentially toxic plant ingestions in children

Development and validation of an LC-MS/MS method for the determination of bullatine A in rat plasma: application to a pharmacokinetic study.

Teng SY1, Zhang SX2, Niu K3, Zhai LJ4, Wang SJ5.
Biomedical chromatography : BMC.Biomed Chromatogr.2015 Dec;29(12):1798-804. doi: 10.1002/bmc.3498. Epub 2015 May 29.
Bullatine A is a diterpenoid alkaloid of Xue-Shang-Yi-Zhi-Hao (Aconitum brachypodum), which is widely used in traditional Chinese medicine for the treatment of rheumatism and pain. The plasma levels of bullatine A were measured by a rapid and sensitive LC-MS/MS method. Samples were prepared using ac
PMID 26033334

Encapsulation of Aconitine in Self-Assembled Licorice Protein Nanoparticles Reduces the Toxicity In Vivo.

Ke LJ1, Gao GZ2, Shen Y3, Zhou JW4, Rao PF5.
Nanoscale research letters.Nanoscale Res Lett.2015 Dec;10(1):449. Epub 2015 Nov 19.
Many herbal medicines and compositions are clinically effective but challenged by its safety risks, i.e., aconitine (AC) from aconite species. The combined use of Radix glycyrrhizae (licorice) with Radix aconite L. effectively eliminates toxicity of the later while increasing efficacy. In this study
PMID 26586149

Qi Y1, Zhao DK2, Zi SH3, Zhang LM3, Guo CX3, Li GQ3, Xun JJ4, Shen Y3.
Journal of Asian natural products research.J Asian Nat Prod Res.2015 Nov 11:1-5. [Epub ahead of print]
Two new C19-diterpenoid alkaloids, straconitines A (1) and B (2), were isolated from the roots of Aconitum straminiflorum. Their structures were elucidated as 14-benzoylducloudine D (1) and 6-hydroxy-14-benzoylducloudine D (2) based on spectroscopic analysis, including IR, ESI-MS, HR-ESI-MS, 1D, and
PMID 26558800

Analysis of 32 toxic natural substances in herbal products by liquid chromatography quadrupole linear ion trap mass spectrometry.

Zeng Y1, Quek YL1, Kee CL1, Low MY1, Bloodworth BC1, Ge X2.
Journal of pharmaceutical and biomedical analysis.J Pharm Biomed Anal.2015 Nov 10;115:169-73. doi: 10.1016/j.jpba.2015.07.005. Epub 2015 Jul 13.
In this study, an LC-MS/MS EPI method was developed for simultaneous determination of 32 toxic natural substances in herbal products. The analytes include aconite alkaloids, lobelia alkaloids, solanaceous alkaloids, digitalis steroid glycosides, strychnine, tetrahydropalmatine etc. They werecommonly
PMID 26210743