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1. 標準療法に対し難治性の甲状腺分化癌：化学療法 differentiated thyroid cancer refractory to standard treatment chemotherapy
2. 悪性腫瘍関連心膜疾患 pericardial disease associated with malignancy

The CAG regimen (low-dose cytarabine, aclarubicin hydrochloride and granulocyte colony-stimulating factor) for the treatment of elderly acute myelomonocytic leukaemia: a case study.

Tsuda T, Okamoto Y, Sakaguchi R, Katayama N, Ota K.SourceDepartment of Blood Transfusion Medicine and Clinical Hematology, Wakayama Medical College, Wakayama City, Japan.
The Journal of international medical research.J Int Med Res.2001 Jan-Feb;29(1):41-7.
Elderly patients with acute myelomonocytic leukaemia (AMMoL) frequently have a poor quality of life after induction of remission using high-intensity treatment; we seek a more appropriate regimen for such patients. An 86-year-old man was hospitalized with a diagnosis of AMMoL (FAB classification M4)
PMID 11277347

Management of malignant pericardial effusion resulting from recurrent cancer with local instillation of aclarubicin hydrochloride.

Kawashima O, Kurihara T, Kamiyoshihara M, Sakata S, Ishikawa S, Morishita Y.SourceDepartment of Surgery, National Sanatorium Nishigunma Hospital, Shibukawa, Gunma, Japan.
American journal of clinical oncology.Am J Clin Oncol.1999 Aug;22(4):396-8.
To determine the efficacy of aclarubicin hydrochloride in local control of malignant pericardial effusion, the authors carried out a trial of pericardial drainage with local administration of this agent in five patients, whose effusions had produced cardiac tamponade. All patients were women, and th
PMID 10440198

Growth-inhibitory effect of combination chemotherapy for human pancreatic cancer cell lines.

Matsuno S, Hisano H, Kobari M, Akaishi S.SourceFirst Department of Surgery, Tohoku University School of Medicine, Sendai, Japan.
Cancer.Cancer.1990 Dec 1;66(11):2369-74.
Sensitivities to anti-tumor drugs, mitomycin C (MMC), aclarubicin hydrochloride (ACR), doxorubicin hydrochloride (ADR), cisplatin, and 5-fluorouracil (5FU), were examined using PK-1, -8, -9, -12, -14, and -16 cell lines derived from human pancreatic cancer. These cell lines showed different sensitiv
PMID 2123126

Aclalubicin/Lipiodol solution(ACR/LPD)with 7% sodium bicarbonate as a material for oil-chemo-embolization:A fundamental study.:A fundamental study

寺嶋吉保,国友一史,古味信彦
Drug Delivery System 6(3), 177-181, 1991
… Water soluble aclalubicin hydrochloride(ACR, Aclacinone<SUP>®</SUP>, Yamanouchi Pharmaceutical Comp. …
NAID 130000747475

Transcatheter arterial chemoembolization therapy for hepatocellular carcinoma using polylactic acid microspheres containing aclarubicin hydrochloride

Mechanism of Enhancement of the Release Rate of Aclarubicin from Poly-β-hydroxybutyric Acid Microspheres by Fatty Acid Esters

久保田美穂,中野眞汎,従二和彦
Chemical & pharmaceutical bulletin 36(1), 333-337, 1988-01-25
… Poly-β-hydroxybutyric acid (PHB) microspheres containing aclarubicin hydrochloride were prepared by a solvent-evaporation process. … The contents of fatty acid esters in the microspheres and the solubility of aclarubicin hydrochloride in the fatty acid esters greatly affected the release rate of the drug from the microspheres. …
NAID 110003626692