腺房細胞癌、膵腺房細胞癌
WordNet
- small room in which a monk or nun lives (同)cubicle
- a device that delivers an electric current as the result of a chemical reaction (同)electric cell
- a room where a prisoner is kept (同)jail cell, prison cell
- (biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals
- any small compartment; "the cells of a honeycomb"
- a small unit serving as part of or as the nucleus of a larger political movement (同)cadre
- pertaining to the individual parts making up an aggregate fruit like a blackberry
- pertaining to one of the small sacs (as in a compound gland) (同)acinous, acinose, acinic
- any malignant tumor derived from epithelial tissue; one of the four major types of cancer
PrepTutorEJDIC
- (刑務所の)『独房』;(修道院の)小さい独居室 / (ミツバチの)みつ房,巣穴 / 小さい部屋 / 『細胞』 / 電池 / 花粉室 / (共産党などの)細胞
- がん,がん腫
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/05/23 08:37:03」(JST)
[Wiki en表示]
Acinar cell carcinoma of the pancreas |
Micrograph of an acinar cell carcinoma of the pancreas. H&E stain.
|
Classification and external resources |
Acinar cell carcinoma of the pancreas, also acinar cell carcinoma, is a rare malignant exocrine tumour of the pancreas. It represents 5% of all exocrine tumours of the pancreas, making it the second most common type of pancreatic cancer.[1] It is abbreviated ACC. It typically has a guarded prognosis.
Contents
- 1 Symptoms
- 2 Pathology
- 3 Treatment
- 4 See also
- 5 References
- 6 External links
Symptoms
CT scan in a patient with acinar cell carcinoma
The disease is more common in men than women and the average age at diagnosis is about 60.[2] Symptoms are often non-specific and include weight loss. A classic presentation, found in around 15% of cases includes subcutaneous nodules (due to fat necrosis) and arthralgias, caused by release of lipase.[3]
Pathology
ACC are associated with increased serum lipase and manifest in the classic presentation as the Schmid triad (subcutaneous fat necrosis, polyarthritis, eosinophilia).[4]
ACC are typically large, up to 10cm, and soft compared to pancreatic adenocarcinoma, lacking its dense stroma. They can arise in any part of the pancreas.[5]
Histomorphologically, the tumour resembles the cells of the pancreatic acini and, typically, have moderate granular cytoplasm that stain with both PAS and PASD.[6]
Treatment
ACC can be treated with a Whipple procedure.
See also
References
- ^ Tobias Jeffrey S., Hochhauser, Daniel, Cancer and its Management, p. 276, 2010 (6th edn), ISBN 1118713257, 9781118713259
- ^ Von Hoff, 23
- ^ Von Hoff, 23
- ^ Jang, SH.; Choi, SY.; Min, JH.; Kim, TW.; Lee, JA.; Byun, SJ.; Lee, JW. (Feb 2010). "[A case of acinar cell carcinoma of pancreas, manifested by subcutaneous nodule as initial clinical symptom].". Korean J Gastroenterol 55 (2): 139–43. doi:10.4166/kjg.2010.55.2.139. PMID 20168061.
- ^ Von Hoff, 23
- ^ Klimstra, DS.; Heffess, CS.; Oertel, JE.; Rosai, J. (Sep 1992). "Acinar cell carcinoma of the pancreas. A clinicopathologic study of 28 cases.". Am J Surg Pathol 16 (9): 815–37. doi:10.1097/00000478-199209000-00001. PMID 1384374.
- "Von Hoff": Daniel D. Von Hoff, Douglas Brian Evans, Ralph H. Hruban, eds. Pancreatic Cancer, 2005, Jones & Bartlett Learning, ISBN 0763721786, 9780763721787
External links
- Acinar cell carcinoma of the pancreas (harvard.edu)
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
- 1. 膵外分泌腫瘍の病理 pathology of exocrine pancreatic neoplasms
- 2. 頭頸部腫瘍の病理 pathology of head and neck neoplasms
- 3. 唾液腺腫瘍:限局性疾患の治療 salivary gland tumors treatment of locoregional disease
- 4. 悪性唾液腺腫瘍:再発性および転移性疾患の治療 malignant salivary gland tumors treatment of recurrent and metastatic disease
- 5. 唾液腺腫瘍:疫学、診断、評価、および病期分類 salivary gland tumors epidemiology diagnosis evaluation and staging
English Journal
- Canine pancreatic clear acinar cell carcinoma showing an unusual mucinous differentiation.
- Pavone S, Manuali E, Eleni C, Ferrari A, Bonanno E, Ciorba A.SourceDepartment of Biopathological Science and Hygiene of Animal and Food Production, Faculty of Veterinary Medicine, University of Perugia, Via S. Costanzo 4, 06126 Perugia, Italy.
- Journal of comparative pathology.J Comp Pathol.2011 Nov;145(4):355-8. Epub 2011 May 14.
- A small solitary pancreatic nodule was identified in a 10-year-old mixed breed male dog. Microscopically, the lesion consisted of neoplastic clear acinar cells with diffuse, marked mucin production. Immunohistochemical and ultrastructural investigations confirmed the exocrine acinar origin of the tu
- PMID 21571301
- Pancreatic acinar cell carcinoma.
- Gravante G, Williams RN, Dennison AR, Bowrey DJ.SourceDepartment of Hepatobiliary and Pancreatic Surgery, Leicester General Hospital, Leicester, United Kingdom.
- Surgery.Surgery.2011 Oct 5. [Epub ahead of print]
- PMID 21982066
Japanese Journal
- 経過が追えた膵体部腺房-内分泌細胞併存癌の1切除例 : 膵腺房細胞癌の早期画像とは
- 関 誠,名取 健,岸 庸二,森村 玲,吉岡 龍二,古賀 倫太郎,斎浦 明夫,山田 恵子,田中 宏子,松枝 清,鹿取 正道,山本 智理子,加藤 洋,市川 和男,太田代 紀子
- 膵臓 = The Journal of Japan Pancreas Society 25(6), 693-701, 2010-12-25
- NAID 10027914723
- 松井 芳夫,矢野 和仁,田村 洋一郎,影山 隆久
- 日本消化器外科学会雑誌 43(12), 1264-1269, 2010-12-01
- 症例は67歳の男性で,食欲不振と体重減少を訴え,精査目的で当院紹介となった.血液生化学検査では,高度の肝機能障害と黄疸を認めた.腹部超音波検査で総胆管の拡張と,胆管内に占居性病変を認めた.腹部MRIで膵頭部に約2cm大のT1で低信号,T2で高信号の病変と,magnetic resonance cholangiopancreatography(以下,MRCP)では下部胆管に隆起性の欠損像を認めた.腹 …
- NAID 110007989295
Related Links
- Acinar cell carcinoma is a rare malignant epithelial neoplasm with predominantly exocrine acinar differentiation and is seen primarily in older men (mean age, 62 years). The presenting symptoms are usually non-specific ...
- Acinic / Acinar / Acinous Cell Carcinoma is a rare salivary gland cancer, comprising approx. 6%-10% of all salivary gland cancers. Salivary Gland cancers themselves only comprise between 0.3% and 0.9% of all ...
Related Pictures
★リンクテーブル★
[★]
- 英
- acinar cell carcinoma, acinar cell carcinoma of the pancreas
- 関
- 腺房細胞癌、膵臓
- 膵癌の5%。腫瘍が産生するリパーゼのために、症例の20%で結節性紅斑様の皮下脂肪壊死(panniculitis)、好酸球増多、多発性関節痛をきたす。予後は極めて悪い(SSUR.633)
[★]
- 英
- acinar cell carcinoma, acinic cell carcinoma
- 関
- 膵腺房細胞癌, 細葉細胞癌、腺房細胞
参考
- http://info.fujita-hu.ac.jp/pathology1/byouri/syourei/syourei46a.htm
[★]
- 英
- acinar carcinoma, acinic cell carcinoma, acinose carcinoma, acinous carcinoma
- 同
- 腺房細胞癌 acinar cell carcinoma acinic cell carcinoma
[★]
- 関
- acini、acinous、acinus
[★]
細胞