WordNet

pertaining to the individual parts making up an aggregate fruit like a blackberry
pertaining to one of the small sacs (as in a compound gland) (同)acinous, acinose, acinic
one of the small drupes making up an aggregate or multiple fruit like a blackberry
one of the small sacs or saclike dilations in a compound gland

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/01/20 19:57:29」(JST)

wiki en

[Wiki en表示]

An acinus (/ˈæsɨnɨs/) (plural, acini; adjective, acinar [/ˈæsɨnər/] or acinous) refers to any cluster of cells that resembles a many-lobed berry, such as a raspberry (acinus is Latin for "berry"). The berry-shaped termination of an exocrine gland, where the secretion is produced, is acinar in form, as is the alveolar sac containing multiple alveoli in the lungs.

Exocrine glands[edit]

Acinar exocrine glands are found in many organs, including:

the stomach^[1]
the sebaceous gland of the scalp
the salivary glands of the tongue^[2]
the liver
the lacrimal glands
the mammary glands
the pancreas ^[3]
the bulbourethral (Cowper's) glands

The thyroid follicles can also be considered of acinar formation but in this case the follicles, being part of an endocrine gland, act as a hormonal deposit rather than to facilitate secretion.
Mucous acini usually stain pale, while serous acini usually stain dark.
The term "acinus" is considered synonymous with alveolus by some sources, but not all.

human acinar cells

Lungs[edit]

The respiratory bronchioles in the lungs terminate in acini, many-lobed sacs containing groupings of alveoli.

References[edit]

^ Histology at OU 51_07 - pyloric stomach
^ Histology at OU 46_03 - sublingual gland
^ BU Histology Learning System: 10405loa

External links[edit]

acinus at eMedicine Dictionary

This anatomy article is a stub. You can help Wikipedia by expanding it.

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 膵外分泌腫瘍の病理 pathology of exocrine pancreatic neoplasms
2. 膵外分泌機能検査 pancreatic exocrine function tests
3. 前立腺の前癌病変：病理および臨床的意義 precancerous lesions of the prostate pathology and clinical implications
4. 前立腺生検 prostate biopsy
5. 肝生検標本の解釈 interpretation of liver biopsy specimens

English Journal

Evaluation of the microvessel density and the expression of metalloproteases 2 and 9 and ttf1 in the different subtypes of lung adenocarcinoma in Tunisia: a retrospective study of 46 cases.

Mlika M1, Makhlouf C, Boudaya MS, Haddouchi C, Tritar F, Mezni F.
Journal of immunoassay & immunochemistry.J Immunoassay Immunochem.2015;36(2):111-8. doi: 10.1080/15321819.2014.899258.
Despite the new available histologic classification of lung cancers, it remains difficult to assess the real prognostic relevance of the different subtypes of lung adenocarcinomas. Facing the prognostic relevance of microvessel density (MVD) and the expression of metalloproteases and thyroid tyrosin
PMID 24689794

EROD activity and cytochrome P4501A induction in liver and gills of Senegal sole Solea senegalensis from a polluted Huelva Estuary (SW Spain).

Oliva M1, Gravato C2, Guilhermino L2, Galindo-Riaño MD3, Perales JA4.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.Comp Biochem Physiol C Toxicol Pharmacol.2014 Nov;166:134-44. doi: 10.1016/j.cbpc.2014.07.010. Epub 2014 Aug 8.
EROD activity and induction cytochrome P4501A in liver and gills of Senegal sole, Solea senegalensis, from a heavy metal and PAH polluted estuary, was studied. Liver and gill CYP1A catalytic activity was assessed at the enzyme activity level-measured as 7-ethoxyresorufin-O-deethylase and cellular lo
PMID 25110325

DAPK3 Suppresses Acini Morphogenesis and is Required for Mouse Development.

Kocher BA1, White LS1, Piwnica-Worms D2.
Molecular cancer research : MCR.Mol Cancer Res.2014 Oct 10. pii: molcanres.0333.2014. [Epub ahead of print]
Death-associated protein kinase (DAPK3) is a serine/threonine kinase involved in various signaling pathways important to tissue homeostasis and mammalian biology. Considered to be a putative tumor suppressor, the molecular mechanism by which DAPK3 exerts its suppressive function is not fully underst
PMID 25304685

Reproducibility of histological subtyping of malignant pleural mesothelioma.

Brčić L1, Jakopović M, Brčić I, Klarić V, Milošević M, Sepac A, Samaržija M, Seiwerth S.
Virchows Archiv : an international journal of pathology.Virchows Arch.2014 Oct 10. [Epub ahead of print]
Malignant pleural mesothelioma (MPM) has a very poor prognosis. Although clinical stage is currently the only reliable prognostic factor, histologic subtyping reportedly also affects prognosis. Some studies propose reclassification of pleomorphic epithelioid as biphasic or sarcomatoid MPM. This stud
PMID 25300229

Japanese Journal

Impact of Sox9 Dosage and Hes1-mediated Notch Signaling in Controlling the Plasticity of Adult Pancreatic Duct Cells in Mice.

Hosokawa Shinichi,Furuyama Kenichiro,Horiguchi Masashi,Aoyama Yoshiki,Tsuboi Kunihiko,Sakikubo Morito,Goto Toshihiko,Hirata Koji,Tanabe Wataru,Nakano Yasuhiro,Akiyama Haruhiko,Kageyama Ryoichiro,Uemoto Shinji,Kawaguchi Yoshiya
Scientific reports 5, 2015-02-17
… In the adult pancreas, there has been a long-standing dispute as to whether stem/precursor populations that retain plasticity to differentiate into endocrine or acinar cell types exist in ducts. … We previously reported that adult Sox9-expressing duct cells are sufficiently plastic to supply new acinar cells in Sox9-IRES-CreERT2 knock-in mice. … Acinar cell differentiation was accelerated by Hes1 inactivation, but suppressed by NICD induction in adult Sox9-expressing cells. …
NAID 120005575180

An Efficient Method is Required to Transfect Non-dividing Cells with Genetically Encoded Optical Probes for Molecular Imaging

, ,
Analytical Sciences 31(4), 293-298, 2015
… To incorporate genetically encoded reporters into the primary culture of non-dividing cells, such as mouse or human pancreatic acinar cells, is not an easy task. … This short review discusses the different methods available to transfect cell lines and primary cultures while especially focusing on pancreatic acinar cells with genetically encoded optical reporters to advance knowledge of the pathophysiology of pancreatitis …
NAID 130005061529

Suspected natural lysosomal storage disease from ingestion of pink morning glory (Ipomoea carnea) in goats in northern Argentina

, , , , , , , ,
Journal of Veterinary Medical Science advpub(0), 2015
… Cytoplasmic vacuolation in the Purkinje cells and pancreatic acinar cells was observed by histological examination. …
NAID 130004781114