English Journal

Anti-ulcer agent teprenone inhibits hepatitis C virus replication: potential treatment for hepatitis C.

Ikeda M1, Kawai Y, Mori K, Yano M, Abe K, Nishimura G, Dansako H, Ariumi Y, Wakita T, Yamamoto K, Kato N.
Liver international : official journal of the International Association for the Study of the Liver.Liver Int.2011 Jul;31(6):871-80. doi: 10.1111/j.1478-3231.2011.02499.x. Epub 2011 Mar 13.
BACKGROUND: Previously we reported that 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, statins, inhibited hepatitis C virus (HCV) RNA replication. Furthermore, recent reports revealed that the statins are associated with a reduced risk of hepatocellular carcinoma and lower portal pressu
PMID 21645219

New biological function of bovine alpha-lactalbumin: protective effect against ethanol- and stress-induced gastric mucosal injury in rats.

Matsumoto H1, Shimokawa Y, Ushida Y, Toida T, Hayasawa H.
Bioscience, biotechnology, and biochemistry.Biosci Biotechnol Biochem.2001 May;65(5):1104-11.
Although several studies have shown that milk protein components have a wide range of biological activities, the potential role of these proteins in the gastrointestinal mucosal defense system is less well elucidated. In this study, we investigated the effect of the major proteins in cow's milk on g
PMID 11440124

[Teprenone in the treatment of chronic superficial gastritis, a multicentre study].

Liu X1, Jia B, Lin S.
Zhonghua nei ke za zhi.Zhonghua Nei Ke Za Zhi.1996 Jan;35(1):12-4.
Teprenone (Selbex), a gastric mucosal protective drug for treatment of chronic gastritis and gastric ulcer, has recently been used in the People's Republic of China. Teprenone in the treatment of chronic superficial gastritis (CSG): a surveillance study was recently conducted in 4 major hospitals in
PMID 9275638

Japanese Journal

内服薬剤の懸濁液によるポリスチレン製器具の溶解現象:-薬剤の懸濁に用いる器具の材質への注意-

朝倉寛達,三科ますみ,倉田なおみ,伊藤喬,雨宮美智子
医療薬学 36(5), 310-315, 2010
… and stirred with a polystyrene (PS) disposable spoon.When left in the suspension,the surface of the spoon started to dissolve after 45 minutes,and was completely dissolved after 12 hours.We also investigated the dissolution of PS utensils in suspensions made from teprenone (Selbex®) capsules or powder,or gefarnate (Gefanil®) capsules.Up till now,there have been no reports of toxicity due to PS or the non-reactants and/or by-products produced in the PS production process.However,as the dissolution of spoons,cups or other common utensils made of PS in …
NAID 130004502598

Venture 門脈圧亢進症性胃症に対するテプレノンの効果

降籏佳功,山岸弘明
細胞 33(10), 384-387, 2001-09
NAID 40005399322

New Biological Function of Bovine α-Lactalbumin : Protective Effect against Ethanol- and Stress-induced Gastric Mucosal Injury in Rats

, , [他], ,
Bioscience, biotechnology, and biochemistry 65(5), 1104-1111, 2001-05-23
… Among the major milk proteins, α-lactalbumin (α-LA) is demonstrated to have a marked protective effect against ethanol-induced gastric injury, with the same potency as that of the typical antiulcer agent, Selbex. …
NAID 110002680400

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