WordNet

any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
the 18th letter of the Roman alphabet (同)r
ancient Egyptian sun god with the head of a hawk; a universal creator; he merged with the god Amen as Amen-Ra to become the king of the gods (同)Re

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RLIP76-Dependent Suppression of PI3K/AKT/Bcl-2 Pathway by miR-101 Induces Apoptosis in Prostate Cancer.

Yang J1, Song Q1, Cai Y1, Wang P1, Wang M1, Zhang D2.
Biochemical and biophysical research communications.Biochem Biophys Res Commun.2015 Jun 8. pii: S0006-291X(15)30095-4. doi: 10.1016/j.bbrc.2015.06.032. [Epub ahead of print]
MicroRNA-101 (miR-101) participates in carcinogenesis and tumor progression in various cancers. However, its biological functions in prostate cancer are still unclear. Here, we demonstrate that miR-101 represents a critical role in regulating cell apoptosis in prostate cancer cells. We first demonst
PMID 26067553

Early step of JSRV-mediated cell transformation involves the interaction between Env and the RALBP1 cellular protein.

Monot M1, Erny A1, Gineys B1, Desloire S1, Dolmazon C1, Aublin-Gex A2, Lotteau V2, Archer F1, Leroux C3.
Journal of virology.J Virol.2015 Jun 3. pii: JVI.00590-15. [Epub ahead of print]
Ovine pulmonary adenocarcinoma is a naturally occurring lung cancer in sheep induced by the Jaagsiekte Sheep RetroVirus (JSRV). Its envelope glycoprotein (Env) carries oncogenic properties, and its expression is sufficient to induce in vitro cell transformation and in vivo lung adenocarcinoma. The i
PMID 26041289

Effects of RAL signal transduction in KRAS- and BRAF-mutated cells and prognostic potential of the RAL signature in colorectal cancer.

Győrffy B1,2,3, Stelniec-Klotz I4, Sigler C4, Kasack K4,5, Redmer T4,5, Qian Y4, Schäfer R4,5.
Oncotarget.Oncotarget.2015 May 30;6(15):13334-46.
Our understanding of oncogenic signaling pathways has strongly fostered current concepts for targeted therapies in metastatic colorectal cancer. The RALA pathway is novel candidate due to its independent role in controlling expression of genes downstream of RAS.We compared RALA GTPase activities in
PMID 26033452

A comparative proteomics study on matrix vesicles of osteoblastlike Saos-2 and U2-OS cells

, , , , ,
Intractable & Rare Diseases Research 2(2), 59-62, 2013
… A label-free quantitative proteomic method was used to compare the protein profiling of MVs from Saos-2 and U2-OS cells. … We further validated that two MVs proteins, protein kinase C α and ras-related protein Ral-A, were up-regulated in MVs of Saos-2 cells compared to those of U2-OS cells under mineralization-induction. …
NAID 130003397563

1) エストロゲン(E)受容体の機能解析と抗老化分子SIRT1のE標的組織への作用に基いた新規ホルモン補充療法の開発に向けた研究(シンポジウム1:女性ヘルスケア「中高年に対する女性医学の展開」,第64回日本産科婦人科学会・学術講演会)

平池修
日本産科婦人科學會雜誌 64(10), 2167-2179, 2012-10-01
… 3) Tissue specific ER function was investigated by concomitant use of conjugated equine estrogen (CEE) and raloxifene (RAL) for patients with decreased bone mineral density. … The subjects exhibited increased bone mineral density by the treatment of CEE plus RAL, and no detrimental side effects were observed by the treatment of CEE plus RAL. …
NAID 110009518073

長谷耕二
腸内細菌学雑誌 = Journal of intestinal microbiology 26(1), 11-17, 2012-01-01
腸管粘膜は，食餌とともに摂取される病原菌やウイルス，さらには100兆個にも及ぶとされる腸内常在細菌に曝されており，常に感染の危険と隣り合わせにある．こうした危険性に対処するため，上皮細胞は堅牢なタイトジャンクションを形成し，体の内と外を隔てる物理的障壁となるのみならず，ムチンバリアの形成や抗菌ペプチドの分泌などを介して，積極的な宿主防御の役割を果たしている．さらに腸管には全末梢リンパ球の60-70 …
NAID 10030171795