WordNet

PrepTutorEJDIC

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 遺伝性疾患の基本原則 basic principles of genetic disease
2. C型肝炎治療を施行しているHIV感染患者のモニタリング monitoring the hiv infected patient taking hepatitis c therapy
3. HIV-1 RNA定量の技術および解釈 techniques and interpretation of hiv 1 rna quantitation
4. 慢性B型肝炎ウイルス感染の試験研究中の治療 investigational treatments of chronic hepatitis b virus infection
5. 分子遺伝学の原理 principles of molecular genetics

Chatake T1.
Methods in molecular biology (Clifton, N.J.).Methods Mol Biol.2016;1320:283-300. doi: 10.1007/978-1-4939-2763-0_18.
The hydration shells surrounding nucleic acids and hydrogen-bonding networks involving water molecules and nucleic acids are essential interactions for the structural stability and function of nucleic acids. Water molecules in the hydration shells influence various conformations of DNA and RNA by sp
PMID 26227050

Nucleic Acid Crystallography via Direct Selenium Derivatization: RNAs Modified with Se-Nucleobases.

Sun H1, Jiang S, Huang Z.
Methods in molecular biology (Clifton, N.J.).Methods Mol Biol.2016;1320:193-204. doi: 10.1007/978-1-4939-2763-0_12.
Selenium-derivatized RNAs are powerful tools for structure and function studies of RNAs and their protein complexes. By taking the advantage of selenium modifications, researchers can determine novel RNA structures via convenient SAD and MAD phasing. As one of the naturally occurring tRNA modificati
PMID 26227044

Identification of transcripts regulated by CUG-BP, Elav-like family member 1 (CELF1) in primary embryonic cardiomyocytes by RNA-seq.

Blech-Hermoni Y1, Ladd AN1.
Genomics data.Genom Data.2015 Dec 1;6:74-76.
CUG-BP, Elav-like family member 1 (CELF1) is a multi-functional RNA binding protein that regulates pre-mRNA alternative splicing in the nucleus, as well as polyadenylation status, mRNA stability, and translation in the cytoplasm [1]. Dysregulation of CELF1 has been implicated in cardiomyopathies in
PMID 26366374

The Development of Ternary Nanoplexes for Efficient Small Interfering RNA Delivery

Şalva Emine,Özbaş Turan Suna,Akbuğa Jülide
Biological and Pharmaceutical Bulletin 36(12), 1907-1914, 2013
… Targeted posttranscriptional gene silencing by RNA interference (RNAi) has garnered considerable interest as an attractive new class of drugs for several diseases, such as cancer. … Chitosan and protamine are commonly used as a vehicle to deliver and protect small interfering RNA (siRNA), but the strong interaction still remains to be modulated for efficient siRNA uptake and silencing. …
NAID 130003382070

阿部洋
YAKUGAKU ZASSHI 133(3), 373-378, 2013
… RNA interference (RNAi) is a potent and highly specific gene-silencing phenomenon which is initiated or triggered by double-stranded RNAs (dsRNAs). … However, natural RNA strands are quickly degraded in biological fluids. … Although these modifications improve the stability of siRNA in serum, they often cause a decrease in RNAi activity. … There is also concern that unnatural RNA derivatives are toxic in the human body. …
NAID 130003361926

Sakurai Haruna,Tsutsui Ayaka,Higashi Takahiro [他],Azuma Rika,Ito Fumiaki,Kawasaki Katsumi
Biological and Pharmaceutical Bulletin 36(7), 1159-1166, 2013
… RecQ5, a member of the RecQ helicase family, maintains genome stability via participation in many DNA metabolic processes including DNA repair, DNA resolution, and RNA transcription, processes occurring in the nucleus. …
NAID 130003361476