WordNet

invest with or as with a body; give body to (同)personify
the external structure of a vehicle; "the body of the car was badly rusted"
the main mass of a thing
a natural object consisting of a dead animal or person; "they found the body in the lake" (同)dead body
the entire structure of an organism (an animal, plant, or human being); "he felt as if his whole body were on fire" (同)organic structure, physical structure
a collection of particulars considered as a system; "a body of law"; "a body of doctrine"; "a body of precedents"
a group of persons associated by some common tie or occupation and regarded as an entity; "the whole body filed out of the auditorium"; "the student body"; "administrative body"
an individual 3-dimensional object that has mass and that is distinguishable from other objects; "heavenly body"
the central message of a communication; "the body of the message was short"

PrepTutorEJDIC

〈C〉『身体』,肉体 / 〈C〉(人・動物の)『胴体』 / 〈C〉)物の)『主要部』,本体《+『of』+『名』》 / 〈C〉(…の)『団体』,群れ:(…のたくさんの)集まり《+『of』+『名』》 / 〈C〉物体,…体 / 〈U〉実質;(酒・味などの)こく / 〈C〉《話》人
《英話》人;(特に)男

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/09/29 10:30:44」(JST)

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Image of a Nissl-stained histological section through the rodent hippocampus showing various classes of cells (neurons and glia).

Motor nerve cell from ventral horn of medulla spinalis of rabbit. The angular and spindle-shaped Nissl bodies are well shown.

A Nissl body, also known as Nissl substance, is a large granular body found in neurons. These granules are of rough endoplasmic reticulum (RER) with rosettes of free ribosomes, and are the site of protein synthesis.^[1] It was named after Franz Nissl, a German neuropathologist who invented the Nissl staining method.^[2]

Nissl bodies can be demonstrated by a method of selective staining developed by Nissl (Nissl staining), using an aniline stain to label extranuclear RNA granules. This staining method is useful to localize the cell body, as it can be seen in the soma and dendrites of neurons, though not in the axon or axon hillock.^[3] Due to RNA's basophilic ("base-loving") properties it is stained blue by this method.

Nissl bodies show changes under various physiological conditions and in pathological conditions they may dissolve and disappear (chromatolysis).

Function

The functions of Nissl bodies is thought to be the same as that of the rest of the ER and the golgi apparatus: the manufacture and release of proteins.^[2]

The ultrastructure of Nissl bodies suggests they are primarily concerned with the synthesis of proteins for intercellular use.^[4]

References

^ John H. Byrne; James Lewis Roberts (23 January 2009). From Molecules to Networks: An Introduction to Cellular and Molecular Neuroscience. Academic Press. pp. 20–. ISBN 978-0-12-374132-5. Retrieved 4 January 2013.
^ ^a ^b Richard H. Thompson (29 March 2000). The Brain: A Neuroscience Primer. Macmillan. pp. 35–. ISBN 978-0-7167-3226-6. Retrieved 4 January 2013.
^ Wolfgang Kühnel (2003). Color Atlas of Cytology, Histology, and Microscopic Anatomy. Thieme. pp. 182–. ISBN 978-3-13-562404-4. Retrieved 4 January 2013.
^ T. Herdegen; J. Delgado-Garcia (25 May 2005). Brain Damage and Repair: From Molecular Research to Clinical Therapy. Springer. pp. 37–. ISBN 978-1-4020-1892-3. Retrieved 4 January 2013.

External links

Nissl Bodies at the US National Library of Medicine Medical Subject Headings (MeSH)
Histology image: 04103loa – Histology Learning System at Boston University - "Nervous Tissue and Neuromuscular Junction: spinal cord, cell bodies of anterior horn cells"
Histology at anhb.uwa.edu.au
Tissues containing Nissl bodies at harvard.edu

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Japanese Journal

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, , [他], , , , , , , ,
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… Two weeks after surgical operation, OVX mice underwent restraint stress for 21 days (6 h/day), and all animals were then subjected to a contextual fear conditioning test followed by morphological examination by Nissl staining. … Chronic treatment with both doses of placental extract improved the OVX/stress-induced fear memory impairment and Nissl-positive cell loss of the hippocampal CA3 region, although it did not affect the loss of bone mineral density and increase in body weight after OVX. …
NAID 10031123550

Ｅｄａｒａｖｏｎｅによる弓部大動脈手術時の脳保護効果

北中陽介,幕内晴朗,村上浩,大野真,安藤敬,田中佳世子,大沼繁子
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, ,
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… Retinal projections and cytoarchitectonic organization of the lateral geniculate nucleus (LGN) in domestic pig (Sus scrofa domesticus Brisson) were studied using the Nissl stain and anterograde transport of horseradish peroxidase (HRP) methods. … In Nissl preparation, both the dorsal LGN (LGNd) and the ventral LGN (LGNv) of the domestic pig were divided into four laminae according to cell organization, respectively. …
NAID 10021721828