非アドレナリン非コリン作動性神経
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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2017/09/02 17:43:47」(JST)
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A non-noradrenergic, non-cholinergic transmitter (NANC) is a neurotransmitter of the autonomic nervous system (ANS) that is neither acetylcholine, norepinephrine, or epinephrine.
Comparison table
This table compares different NANCs in the PNS:
Neurotransmitter |
Type |
Location[1] |
Function[1] |
ATP |
non-peptide |
postganglionic sympathetic neurons (e.g. in blood vessels & vas deferens) |
Fast depolarization/contraction (vasoconstriction) |
GABA |
non-peptide |
ENSs |
peristalsis |
5-HT |
non-peptide |
ENSs |
peristalsis |
dopamine |
non-peptide |
some SNSs (e.g. kidney) |
vasodilation |
NO |
non-peptide |
gastric nerves & Pelvic Nerve |
- erection
- gastric emptying
|
NPY |
peptide |
postganglionic sympathetic neurons (e.g. blood vessels) |
- enhance vasoconstrictor action of noradrenaline
- noradrenaline release inhibitor
|
VIP |
peptide |
- parasympathetic nerves to salivary glands
- NANC innervation to smooth muscle of airways
- parasympathetic ganglia in sphincters, gallbladder and small intestine
|
- vasodilation
- acetylcholine cotransmitter
- bronchodilation
- relaxation of intestinal smooth muscle and sphincters
|
GnRH |
peptide |
sympathetic ganglia |
- slow depolarization
- acetylcholine cotransmitter
|
substance P |
peptide |
|
- slow depolarization
- acetylcholine cotransmitter
|
CGRP |
peptide |
non-myelinated sensory neurons |
- vasodilation
- increase vascular permeability
- neurogenic inflammation
|
References
- ^ a b Unless else specified in table, then ref is: Rang, H. P. (2003). Pharmacology. Edinburgh: Churchill Livingstone. ISBN 0-443-07145-4. Page 132
Neurotransmitters
|
Amino acid-derived |
- Major excitatory/inhibitory systems: Glutamate system: Agmatine
- Aspartic acid (aspartate)
- Cycloserine
- Glutamic acid (glutamate)
- Glutathione
- Glycine
- GSNO
- GSSG
- Kynurenic acid
- NAA
- NAAG
- Proline
- Serine; GABA system: GABA
- GABOB
- GHB; Glycine system: α-Alanine
- β-Alanine
- Glycine
- Hypotaurine
- Proline
- Sarcosine
- Serine
- Taurine; GHB system: GHB
- T-HCA (GHC)
- Biogenic amines: Monoamines: 6-OHM
- Dopamine
- Epinephrine (adrenaline)
- NAS (normelatonin)
- Norepinephrine (noradrenaline)
- Serotonin (5-HT); Trace amines:
- 3-Iodothyronamine
- N-Methylphenethylamine
- N-Methyltryptamine
- m-Octopamine
- p-Octopamine
- Phenylethanolamine
- Phenethylamine
- Synephrine
- Tryptamine
- m-Tyramine
- p-Tyramine; Others: Histamine
- Neuropeptides: See here instead.
|
Lipid-derived |
- Endocannabinoids: 2-AG
- 2-AGE (noladin ether)
- 2-ALPI
- 2-OG
- AA-5-HT
- Anandamide (AEA)
- DEA
- LPI
- NADA
- NAGly
- OEA
- Oleamide
- PEA
- RVD-Hpα
- SEA
- Virodhamine (O-AEA)
- Neurosteroids: See here instead.
|
Nucleobase-derived |
- Nucleosides: Adenosine system: Adenosine
- ADP
- AMP
- ATP
|
Vitamin-derived |
- Cholinergic system: Acetylcholine
|
Miscellaneous |
- Gasotransmitters: Carbon monoxide (CO)
- Hydrogen sulfide (H2S)
- Nitric oxide (NO); Candidates: Acetaldehyde
- Ammonia (NH3)
- Carbonyl sulfide (COS)
- Nitrous oxide (N2O)
- Sulfur dioxide (SO2)
|
UpToDate Contents
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English Journal
- Vagally-mediated gastric effects of brainstem α2 adrenoceptor activation in stressed rats.
- Jiang Y1, Browning KN2, Toti L1, Travagli RA2.
- American journal of physiology. Gastrointestinal and liver physiology.Am J Physiol Gastrointest Liver Physiol.2018 Jan 11. doi: 10.1152/ajpgi.00382.2017. [Epub ahead of print]
- PMID 29351390
- Possible relationship between antiphospholipid antibodies and embolic events in infective endocarditis.
- Selton-Suty C1, Maigrat CH1, Devignes J2, Goehringer F3, Erpelding ML4, Alla F4, Thivilier C5, Huttin O1, Venner C1, Juilliere Y1, Doco-Lecompte T6, Lecompte T7,8; Endocarditis Team of the University Hospital of Nancy, France.
- Heart (British Cardiac Society).Heart.2018 Jan 5. pii: heartjnl-2017-312359. doi: 10.1136/heartjnl-2017-312359. [Epub ahead of print]
- PMID 29305562
- Study on effects of electrical stimulation on rabbit esophageal body motility in vivo.
- Zhang L1, Zhao W, Zhao C, Jin H, Wang B, Wang B.
- Physiological research.Physiol Res.2018 Jan 5. [Epub ahead of print]
- PMID 29303604
Japanese Journal
- Purinergic Signalling : Pathophysiology and Therapeutic Potential
- Na⁺/Ca²⁺ Exchanger 1/2 Double-Heterozygote Knockout Mice Display Increased Nitric Oxide Component and Altered Colonic Motility
- 可変ステップサイズを有するFXLMSを用いた狭帯域能動騒音制御システム
- 電子情報通信学会技術研究報告. EMM, マルチメディア情報ハイディング・エンリッチメント = IEICE technical report. EMM, Enriched multimedia 112(293), 147-152, 2012-11-09
- NAID 110009642292
Related Pictures
★リンクテーブル★
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- 関
- nonadrenergic noncholinergic relaxation
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- 関
- nonadrenergic noncholinergic nerve
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