WordNet
- a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response
- the 13th letter of the Roman alphabet (同)m
- hormone secreted by the pineal gland
PrepTutorEJDIC
- =sense organ / 受信装置
- Mach number / mark[s] / Monsieur
- Montana
UpToDate Contents
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- 1. メラトニンの生理学および臨床使用 physiology and clinical use of melatonin
- 2. 時差ぼけ jet lag
- 3. 不眠症の治療 treatment of insomnia
- 4. 成人における肝性脳症：治療 hepatic encephalopathy in adults treatment
- 5. 肝性脳症：病因 hepatic encephalopathy pathogenesis
English Journal
- Mechanisms of Esophageal Protection, Gastroprotection and Ulcer Healing by Melatonin. Implications for the Therapeutic Use of Melatonin in Gastroesophageal Reflux Disease (GERD) and Peptic Ulcer Disease.
- Brzozowska I, Strzalka M, Drozdowicz D, Konturek SJ, Brzozowski T.SourceDepartment of Physiology Jagiellonian University Medical College 16 Grzegorzecka Street, 31-531 Cracow, Poland. mpbrzozo@cyf-kr.edu.pl.
- Current pharmaceutical design.Curr Pharm Des.2013 Nov 18. [Epub ahead of print]
- Melatonin is a potent reactive oxygen metabolite scavenger and antioxidant that has been shown to influence many physiological functions of the gastrointestinal (GI) tract including secretion, motility, digestion and absorption of nutrients. The role of melatonin in gastroduodenal defense and ulcer
- PMID 24251671
- MT1 and MT2 Melatonin Receptors: Ligands, Models, Oligomers, and Therapeutic Potential.
- Zlotos DP, Jockers R, Cecon E, Rivara S, Witt-Enderby PA.SourceDepartment of Pharmaceutical Chemistry, The German University in Cairo , New Cairo City, 11835 Cairo, Egypt.
- Journal of medicinal chemistry.J Med Chem.2013 Nov 14. [Epub ahead of print]
- Numerous physiological functions of the pineal gland hormone melatonin are mediated via activation of two G-protein-coupled receptors, MT1 and MT2. The melatonergic drugs on the market, ramelteon and agomelatine, as well as the most advanced drug candidates under clinical evaluation, tasimelteon and
- PMID 24228714
- Subcellular distribution of melatonin receptors in human parotid glands.
- Isola M, Ekström J, Diana M, Solinas P, Cossu M, Lilliu MA, Loy F, Isola R.SourceDepartment of Biomedical Sciences, University of Cagliari, Monserrato, Italy.
- Journal of anatomy.J Anat.2013 Nov;223(5):519-24. doi: 10.1111/joa.12105. Epub 2013 Sep 3.
- The hormone melatonin influences oral health through a variety of actions, such as anti-inflammatory, anti-oxidant, immunomodulatory and antitumour. Many of these melatonin functions are mediated by a family of membrane receptors expressed in the oral epithelium and salivary glands. Using immunoblot
- PMID 23998562
Japanese Journal
- メラトニン受容体作動薬ラメルテオン(ロゼレム^【○!R】錠8mg)の薬理作用と臨床試験成績
- 平井 圭介,加藤 浩紀,西川 久夫,行弘 信仁,西山 啓次,宮本 政臣
- 日本薬理学雑誌 136(1), 51-60, 2010-07-01
- … 弛緩作用，前向性健忘，反跳性不眠，依存性などの種々の有害作用を惹起する．これに対してラメルテオン（Ramelteon，TAK-375，商品名Rozerem®）は，主に視床下部視交叉上核に存在するメラトニン受容体（MT1/MT2受容体）にアゴニストとして作用してcAMP産生系を抑制し，サルおよびネコで強力な睡眠誘発作用を示した．その睡眠パターンは自然睡眠に極めて近いものであった．また，既存薬で見られる学習記憶障害，運 …
- NAID 10026544589
- Acute effects of melatonin and its time of administration on core body temperature and heart rate in cynomolgus monkeys
- INUI Yoshitaka,HAZEKI Osamu
- Journal of toxicological sciences 35(3), 383-391, 2010-06-01
- … We examined the effects of exogenous melatonin and the time of its administration on core body temperature (CBT) and heart rate (HR) in cynomolgus monkeys. … Doses of melatonin at 0.2, 2, 20 and 200 mg/kg were administered by oral gavage once daily at different times. … With administration at 09.00 h, melatonin dose-dependently suppressed CBT and the effect reached statistical significance at 200 mg/kg. …
- NAID 10026469845
Related Links
- Receptor, Melatonin, Mt2; Melatonin MT2 Receptor. On-line free medical diagnosis assistant. Ranked list of possible diseases from either several symptoms or a full patient history. A similarity measure between symptoms and ... ...
- BioInfoBank Library :: Receptor, Melatonin, MT2 :: antagonists & inhibitors :: Toward the definition of stereochemical requirements for MT2-selective antagonists and partial agonists by studying 4-phenyl-2-propionamidotetralin ...
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★リンクテーブル★
| リンク元 | 「MT2メラトニン受容体」「MT2 receptor」「MT2メラトニンレセプター」 |
| 関連記事 | 「MT」「melatonin receptor」「M」 |
「MT2メラトニン受容体」
「MT2 receptor」
「MT2メラトニンレセプター」
「MT」