マトリックスメタロプロテアーゼ
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English Journal
- Activation of aryl hydrocarbon receptor promotes invasion of clear cell renal cell carcinoma and is associated with poor prognosis and cigarette smoke.
- Ishida M1,2, Mikami S3, Shinojima T1, Kosaka T1, Mizuno R1, Kikuchi E1, Miyajima A1, Okada Y4, Oya M1.
- International journal of cancer. Journal international du cancer.Int J Cancer.2015 Jul 15;137(2):299-310. doi: 10.1002/ijc.29398. Epub 2015 Jan 8.
- Although exposure to environmental pollutants is one of the risk factors for renal cell carcinoma (RCC), its relationship with carcinogenesis and the progression of RCC remains unknown. The present study was designed to elucidate the role of the aryl hydrocarbon receptor (AhR), a major mediator of c
- PMID 25523818
- Selective inhibition of prostaglandin E2 receptors EP2 and EP4 modulates DNA methylation and histone modification machinery proteins in human endometriotic cells.
- Arosh JA1, Lee J2, Starzinski-Powitz A3, Banu SK2.
- Molecular and cellular endocrinology.Mol Cell Endocrinol.2015 Jul 5;409:51-8. doi: 10.1016/j.mce.2015.03.023. Epub 2015 Apr 2.
- Endometriosis is an inflammatory gynecological disease of reproductive-age women. The prevalence of endometriosis is 5-10% in reproductive-age women. Modern medical treatments are directed to inhibit the action of estrogen in endometriotic cells. However, hormonal therapies targeting estrogen can be
- PMID 25843056
- Melatonin causes regression of endometriotic implants in rats by modulating angiogenesis, tissue levels of antioxidants and matrix metalloproteinases.
- Yilmaz B1, Kilic S, Aksakal O, Ertas IE, Tanrisever GG, Aksoy Y, Lortlar N, Kelekci S, Gungor T.
- Archives of gynecology and obstetrics.Arch Gynecol Obstet.2015 Jul;292(1):209-16. doi: 10.1007/s00404-014-3599-4. Epub 2014 Dec 19.
- PURPOSE: The aim of this study was to test if melatonin causes regression of endometriotic implants and whether it influences implant levels of superoxide dismutase (SOD), malondialdehyde (MDA), vascular endothelial growth factor (VEGF), tissue inhibitor of metalloproteinase (TIMP)-2 and matrix meta
- PMID 25524539
Japanese Journal
- 中村賞受賞者 難治性網膜硝子体疾患における線維性増殖組織形成に対するSex hormoneの作用
- 木村 和博
- 山口医学 = Yamaguchi medical journal 64(1), 11-16, 2015-02
- … As a result, the female hormones suppressed cell contraction of RPE cells, MMPs expression and EMT. …
- NAID 120005601211
- Expression of matrix metalloproteinases in bovine luteal cells induced by prostaglandin F2α, interferon γ and tumor necrosis factor α
- ABE Hironori,SAKUMOTO Ryosuke,OKUDA Kiyoshi
- Journal of Reproduction and Development 61(4), 277-286, 2015
- … Matrix metalloproteinases (MMPs) can degrade the extracellular matrix and basal membrane, and tissue inhibitors of matrix metalloproteinases (TIMPs) inhibit the activity of MMPs. … To test the hypothesis that MMP expression in luteal cells is regulated by luteolytic factors, we investigated the effects of prostaglandin F2α (PGF), interferon γ (IFNG) and tumor necrosis factor α (TNF) on the mRNA expression of MMPs and TIMPs in cultured luteal cells. …
- NAID 130005094650
- Human Vascular Wall Mesenchymal Stromal Cells Contribute to Abdominal Aortic Aneurysm Pathogenesis Through an Impaired Immunomodulatory Activity and Increased Levels of Matrix Metalloproteinase-9
- Ciavarella Carmen,Alviano Francesco,Gallitto Enrico,Ricci Francesca,Buzzi Marina,Velati Claudio,Stella Andrea,Freyrie Antonio,Pasquinelli Gianandrea
- Circulation Journal 79(7), 1460-1469, 2015
- … Background:The main histopathological features of abdominal aortic aneurysm (AAA) are tissue proteolysis mediated by matrix metalloproteinases (MMPs) and inflammation. …
- NAID 130005083945
Related Links
- (株)ゼネテック 第一システム本部 開発一部 部長/湯原 哲郎さん MMPSの講義は技術経営、人材管理、財務、商品開発、マーケティングと多岐に渡り、それぞれに専門分野の講師陣が経験を踏まえながら ...
- マトリックスメタロプロテアーゼ(MMPs)は,種々の疾患と関連が報告されており,これらの中でも最も研究が進んでいるのが腫瘍との関連である.固形腫瘍がある一定 以上大きくなるためには,腫瘍に栄養や酸素を供給するための ...
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- 英
- matrix metalloproteinase, MMP, matrix metalloproteinases, MMPs
- 同
- マトリックスメタロプロテイナーゼ、マトリックスメタロプロティナーゼ、基質メタロプロテイナーゼ、基質メタロプロティナーゼ、基質メタロプロテアーゼ
- 関
- 細胞外基質分解酵素、細胞外マトリックス分解酵素
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マトリックスメタロプロテアーゼ matrix metalloproteinase