English Journal

Population pharmacokinetics of levofloxacin in Korean patients.

Kiem S, Ryu SM, Lee YM, Schentag JJ, Kim YW, Kim HK, Jang HJ, Joo YD, Jin K, Shin JG, Ghim JL.
Journal of chemotherapy (Florence, Italy).J Chemother.2015 May 15:1973947815Y0000000033. [Epub ahead of print]
Levofloxacin (LVFX) has different effects depending on the area under the concentration-time curve (AUC)/minimum inhibitory concentration (MIC) ratio. While AUC can be expressed as dose/clearance (CL), we measured serial concentrations of LVFX in Koreans and tried to set a Korean-specific equation,
PMID 25976699

Association of overexpression of efflux pump genes with antibiotic resistance in Pseudomonas aeruginosa strains clinically isolated from urinary tract infection patients.

Shigemura K1, Osawa K2, Kato A3, Tokimatsu I4, Arakawa S1, Shirakawa T5, Fujisawa M6.
The Journal of antibiotics.J Antibiot (Tokyo).2015 Apr 8. doi: 10.1038/ja.2015.34. [Epub ahead of print]
There are several mechanisms for antibiotic-resistant Pseudomonas aeruginosa. The purpose of this study is to investigate the association between the expression of efflux pump-coding genes and antibiotic resistance in P. aeruginosa causing urinary tract infections (UTIs). We extracted the RNA from 1
PMID 25850341

Exploration of a standard treatment for Buruli ulcer through a comprehensive analysis of all cases diagnosed in Japan.

Sugawara M1, Ishii N, Nakanaga K, Suzuki K, Umebayashi Y, Makigami K, Aihara M.
The Journal of dermatology.J Dermatol.2015 Mar 26. doi: 10.1111/1346-8138.12851. [Epub ahead of print]
Buruli ulcer (BU) is a refractory skin ulcer caused by Mycobacterium ulcerans or M. ulcerans ssp. shinshuense, a subspecies thought to have originated in Japan or elsewhere in Asia. Although BU occurs most frequently in tropical and subtropical areas such as Africa and Australia, the occurrence in
PMID 25809502

Japanese Journal

短期間のCAM,AMK,IPM/cs併用からCAM,LVFX長期内服へのスイッチ療法により軽快した肺M. abscessus感染症の1例

橋口波子,猪島尚子,猪島一朗
結核 90(6), 549-552, 2015-06
NAID 40020510384

腸管外からAeromonas属菌が検出された症例の基礎的解析

下地法明,村山未来,古野貴未,上地あゆみ,玉城格,手登根稔,赤津義文,大塚喜人
医学検査 64(3), 295-301, 2015
… 抗菌薬感受性検査では，TAZ/PIPC，CTX，CAZ，IPM/CS，GM，LVFX，STに良好な感受性率を示し，一方でSBT/ABPC，CEZにはほとんど耐性であった。 …
NAID 130005087802

ESBL産生/キノロン耐性大腸菌の存在を見据えた高齢者尿路感染症の抗菌薬治療を考察する

山本章,山﨑紘一
日本老年医学会雑誌 52(2), 153-161, 2015
… としてのレボフロキサシン（LVFX）と，注射薬として③スルバクタム配合セフォペラゾン（SBT/CPZ），④メロペネム（MEPM），の計4種の治療効果を比較検討した．治療後に一般病原細菌が検出されなかった場合に治療有効と判定した．結果：①内服薬組み合わせ群での全病原細菌に対する治療有効率は9/11=82%で，ESBL産生大腸菌は結果不明例を除く4例でいずれも消失，②LVFX群では15例中3例に治療前，ま …
NAID 130005071295

Related Pictures

Pep-4, LVFX, melittin, and indolicidin , Shuffle 1.1 and LVFX Variety Pack on 3rd February 2015 by LVFX Frontiers | Covalent modification of a ten lvfx_numa 感受性検査 cpfx lvfx には LVFX：レボフロキサシン