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1. 内臓リーシュマニア症：疫学と管理 visceral leishmaniasis epidemiology and control
2. 内臓リーシュマニア症：臨床症状と診断 visceral leishmaniasis clinical manifestations and diagnosis
3. 内臓リーシュマニア症：治療 visceral leishmaniasis treatment
4. 北アフリカへの旅行によって感染する可能性のある疾患 diseases potentially acquired by travel to north africa
5. 輸血合併症の予防のための白血球除去 leukoreduction to prevent complications of blood transfusion

Synthesis, characterization, and antileishmanial activities of gold(I) complexes involving quinoline functionalized N-heterocyclic carbenes.

Paloque L1, Hemmert C2, Valentin A1, Gornitzka H3.
European journal of medicinal chemistry.Eur J Med Chem.2015 Apr 13;94:22-9. doi: 10.1016/j.ejmech.2015.02.046. Epub 2015 Feb 25.
A series of new mononuclear cationic or neutral gold(I) complexes containing quinoline functionalized N-heterocyclic carbene(s) (NHC(s)) were synthesized and fully characterized by spectroscopic methods. The X-ray structures of two key compounds are presented. Proligands and their corresponding gold
PMID 25747497

Evaluation of adjuvant activity of fractions derived from Agaricus blazei, when in association with the recombinant LiHyp1 protein, to protect against visceral leishmaniasis.

de Jesus Pereira NC1, Régis WC2, Costa LE1, de Oliveira JS3, da Silva AG4, Martins VT3, Duarte MC1, de Souza JR5, Lage PS1, Schneider MS1, Melo MN6, Soto M7, Soares SA5, Tavares CA3, Chávez-Fumagalli MA1, Coelho EA8.
Experimental parasitology.Exp Parasitol.2015 Apr 3. pii: S0014-4894(15)00089-2. doi: 10.1016/j.exppara.2015.03.027. [Epub ahead of print]
The development of effective prophylactic strategies to prevent leishmaniasis has become a high priority. No less important than the choice of an antigen, the association of an appropriate adjuvant is necessary to achieve a successful vaccination, as the majority of the tested antigens contain limit
PMID 25845753

Finding of leishmanicidal activity of 14-hydroxylunularin in mice experimentally infected with Leishmania infantum.

Serna ME1, Maldonado M2, Torres S2, Schinini A3, Peixoto de Abreu Lima A4, Pandolfi E5, Rojas de Arias A6.
Parasitology international.Parasitol Int.2015 Apr 3. pii: S1383-5769(15)00057-4. doi: 10.1016/j.parint.2015.03.005. [Epub ahead of print]
In this study, we report the in vivo efficacy of 14-hydroxylunularin evaluated in BALB/c mice experimentally infected with promastigotes of Leishmania infantum (syn L. chagasi), the major causative agent of visceral leishmaniasis in Latin America. Seven days post-infection, treatment with 14-hydroxy
PMID 25843766