関: D-glucose、dextrose、glucose

WordNet

an isomer of glucose that is found in honey and sweet fruits (同)dextroglucose, grape_sugar
the 12th letter of the Roman alphabet (同)l
a monosaccharide sugar that has several forms; an important source of physiological energy

PrepTutorEJDIC

右旋糖,ぶどう糖
lira(イタリアの貨幣単位リラ)
ブドウ糖
liter[s]

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/08/20 19:18:11」(JST)

wiki en

L-Glucose is an organic compound with formula C₆H₁₂O₆ or H–(C=O)–(CHOH)₅–H, specifically one of the aldohexose monosaccharides. As the L-isomer of glucose, it is the enantiomer of the more common D-glucose.

L-Glucose does not occur naturally in higher living organisms, but can be synthesized in the laboratory. L-Glucose is indistinguishable in taste from D-glucose,^[1] but cannot be used by living organisms as source of energy because it cannot be phosphorylated by hexokinase, the first enzyme in the glycolysis pathway. One of the known exceptions is in Burkholderia caryophylli, a plant pathogenic bacterium, which contains the enzyme D-threo-aldose 1-dehydrogenase which is capable of oxidizing L-glucose^[2]

Like the 'D-' isomer, L-glucose usually occurs as one of four cyclic structural isomers — α- and β-L-glucopyranose (the most common, with a six-atom ring), and α- and β-L-glucofuranose (with a five-atom ring). In water solution, these isomers interconvert in matters of hours, with the open-chain form as an intermediate stage.

Uses

L-Glucose was once proposed as a low-calorie sweetener and it is suitable for patients with diabetes mellitus, but it was never marketed due to excessive manufacturing costs.^[1]

The acetate derivative of L-glucose, L-glucose pentaacetate, was found to stimulate insulin release, and might therefore be of therapeutic value for type 2 diabetes.^[3] L-Glucose was also found to be a laxative, and has been proposed as a colon-cleansing agent which would not produce the disruption of fluid and electrolyte levels associated with the significant liquid quantities of (bad-tasting) osmotic laxatives conventionally used in preparation for colonoscopy.^[4]

References

^ ^a ^b A Natural Way to Stay Sweet, NASA, retrieved 2009-09-02 .
^ Sasajima, K.; Sinskey, A. (1979). "Oxidation of l-glucose by a Pseudomonad". Biochimica et Biophysica Acta (BBA) - Enzymology 571: 120–126. doi:10.1016/0005-2744(79)90232-8. edit
^ Malaisse, W. J. (1998), "The riddle of L-glucose pentaacetate insulinotropic action", Int. J. Mol. Med. 2 (4): 383–88, doi:10.3892/ijmm.2.4.383 .
^ Raymer, Geoffrey S.; Hartman, Donald E.; Rowe, William A.; Werkman, Robert F.; Koch, Kenneth L. (2003), "An open-label trial of L-glucose as a colon-cleansing agent before colonoscopy", Gastrointest. Endosc. 58 (1): 30–35, doi:10.1067/mge.2003.293, PMID 12838217

UpToDate Contents

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1. 2型糖尿病のスクリーニング screening for type 2 diabetes mellitus
2. 乳児および小児における低血糖に対するアプローチ approach to hypoglycemia in infants and children
3. 成人糖尿病患者のマネージメントにおける血糖の自己モニタリング（SMBG） blood glucose self monitoring in management of adults with diabetes mellitus
4. 糖尿病の治療における低血糖のマネージメント management of hypoglycemia during treatment of diabetes mellitus
5. 小児および思春期における2型糖尿病の疫学、症状、および診断 epidemiology presentation and diagnosis of type 2 diabetes mellitus in children and adolescents

English Journal

Classification of red wines using suitable markers coupled with multivariate statistic analysis.

Geana EI1, Popescu R2, Costinel D2, Dinca OR2, Ionete RE2, Stefanescu I2, Artem V3, Bala C4.
Food chemistry.Food Chem.2016 Feb 1;192:1015-24. doi: 10.1016/j.foodchem.2015.07.112. Epub 2015 Jul 23.
Methodologies for chemometric classification of five authentic red wine varieties from Murfatlar wine center, Romania, young and aged are reported. The discriminant analysis based on several anthocyanins, organic acids, (13)C/(12)C, (18)O/(16)O and D/H isotopic ratios, (1)H and (13)C NMR fingerprint
PMID 26304442

Acrylamide and 5-hydroxymethylfurfural formation during baking of biscuits: Part I: Effects of sugar type.

Nguyen HT1, Van der Fels-Klerx HJ2, Peters RJ1, Van Boekel MA3.
Food chemistry.Food Chem.2016 Feb 1;192:575-85. doi: 10.1016/j.foodchem.2015.07.016. Epub 2015 Jul 11.
This study aimed to investigate the effects of sugar type on the reaction mechanism for formation of acrylamide and 5-hydroxymethylfurfural (HMF) during the baking of biscuits at 200°C using multiresponse modelling. Four types of biscuits were prepared: (1) with sucrose, (2) with glucose and fructo
PMID 26304386

Physicochemical profiles of stingless bee (Apidae: Meliponini) honey from South East Asia (Thailand).

Chuttong B1, Chanbang Y2, Sringarm K3, Burgett M4.
Food chemistry.Food Chem.2016 Feb 1;192:149-55. doi: 10.1016/j.foodchem.2015.06.089. Epub 2015 Jun 26.
This study examines the physicochemical properties of stingless bee honey from SE Asia (Thailand). Twenty-eight stingless bee honey samples, from 11 stingless bee species, were examined. Results reveal an average color (67±19mm Pfund), moisture (31±5.4g/100g), ash (0.531±0.632g/100g), electrical
PMID 26304332

Japanese Journal

牛皮を用いた糖化反応のモデル作製

一條遼,八木雅之,千速夕季,神谷有美,明和司将,西田周平,下出昭彦,埜本慶太郎,米井嘉一
同志社大学理工学研究報告 53(2), 67-70, 2012-07
… 今回、我々は牛皮を2mol/Lグルコースに浸透し、60℃、6日間インキュベートした糖化反応のモデルを作製した。 … Glycation is a non-enzymatic reaction between a protein and a reducing sugar, such as glucose, that forms advanced glycation end products (AGEs). … Here, we developed a model of glycation reaction by using a bovine skin incubated with 2mol/L glucose at 60°C for 6 days. …
NAID 110009443885

Biofilm formation by Streptococcus pyogenes : Modulation of exopolysaccharide by fluoroquinolone derivatives(MICROBIAL PHYSIOLOGY AND BIOTECHNOLOGY)

Shafreen Raja Mohmed Beema,Srinivasan Shanmugam,Manisankar Paramasivam,Pandian Shunmugiah Karutha
Journal of bioscience and bioengineering 112(4), 345-350, 2011-10
… pyogenes has the most abundant neutral sugars L-glucose and D-mannose which is not detected in the fluoroquinolone treated EPS. …
NAID 110008761489

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★リンクテーブル★

リンク元	「L-グルコース」「D-glucose」
関連記事	「L」

「L-グルコース」

L-Glucose
Names
	IUPAC name L-Glucose
Identifiers
CAS Registry Number	921-60-8
Abbreviations	L-Glc
ChEBI	CHEBI:37627
ChemSpider	2006622
EC number	213-068-3
	InChI InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6?/m0/s1 ; Key: WQZGKKKJIJFFOK-ZZWDRFIYSA-N ; InChI=1/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6?/m0/s1; Key: WQZGKKKJIJFFOK-ZZWDRFIYBQ ;
Jmol-3D images	Image
PubChem	2724488
	SMILES O[C@@H]1[C@@H](O)[C@@H](OC(O)[C@H]1O)CO ;
Properties
Chemical formula	C6H12O6
Molar mass	180.16 g·mol−1
Density	1.54 g/cm3
Solubility in water	91 g/100 mL
Hazards
Safety data sheet	ICSC 0865
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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	Infobox references