ケブネル現象
WordNet
- any state or process known through the senses rather than by intuition or reasoning
- a remarkable development
PrepTutorEJDIC
- 『現象』 / 驚くべきこと(物),非凡な人
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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/04/22 16:28:48」(JST)
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Heinrich Köbner (1838-1904)
The Koebner phenomenon or Köbner phenomenon (pronunciation), also called the "Koebner response" or the "isomorphic response", refers to skin lesions appearing on lines of trauma.[1] The Koebner phenomenon may result from either a linear exposure or irritation. Conditions demonstrating linear lesions after a linear exposure to a causative agent include: molluscum contagiosum, warts and toxicodendron dermatitis (a dermatitis caused by a genus of plants including poison ivy). Warts and molluscum contagiosum lesions can be spread in linear patterns by self-scratching ("auto-inoculation"). Toxicodendron dermatitis lesions are often linear from brushing up against the plant. Causes of the Koebner phenomenon that are secondary to scratching rather than an infective or chemical cause include vitiligo, psoriasis, lichen planus, lichen nitidus, pityriasis rubra pilaris, and keratosis follicularis (Darier disease).[citation needed]
Contents
- 1 Definition
- 2 History
- 3 References
- 4 Sources
- 5 See also
Definition
The Koebner phenomenon describes skin lesions which appear at the site of injury. It is seen in:[2]
-
- Psoriasis
- Pityriasis rubra pilaris
- Lichen planus
- Lichen nitidus
- Vitiligo
- Lichen sclerosus
- Elastosis perforans serpiginosa
- Kaposi sarcoma
- Necrobiosis lipoidica
- Systemic Lupus Erythematosus
- Juvenile Idiopathic Arthritis
- Still disease
A similar response occurs in pyoderma gangrenosum and Adamantiades-Behcet's syndrome, and is referred to as pathergy.[2]
Rarely Koebner phenomenon has been reported as a mechanism of acute myeloid leukemia dissemination.[3]
Warts and molluscum contagiosum are often listed as causing a Koebner reaction, but this is by direct inoculation of viral particles.[2]
The linear arrangement of skin lesions in the Koebner phenomenon can be contrasted to both lines of Blaschko and dermatomal distributions. Blaschko lines follow embryotic cell migration patterns and are seen in some mosaic genetic disorders such as incontinentia pigmenti and pigment mosaicism. Dermatomal distributions are lines on the skin surface following the distribution of spinal nerve roots. The rash caused by herpes zoster (Shingles) follows such dermatomal lines.[citation needed]
History
The Koebner phenomenon was named after a rather eccentric, renowned German dermatologist, Heinrich Koebner[4] (1838–1904). Koebner is best known for his work in mycology. Here is one story to illustrate his intense nature: in a medical meeting he proudly exhibited on his arms and chest three different fungus infections, which he self-inoculated in order to prove the infectiousness of the organisms he was studying. The Koebner phenomenon was the generalized term applied to his discovery that on psoriasis patients new lesions often appear on lines of trauma, which are often linear.[citation needed]
Pronunciation
A typical pronunciation in English approximates the front rounded vowel ö (/ø/ or /œ/) with an /r/ sound (//).[5]
References
- ^ Various grammatical forms of "Koebner phenomenon" include: "Koebnerization", and "to Koebnerize".
- ^ a b c Cox, Gary M. White; Neil H. (2000). Diseases of the skin : a color atlas and text. London [u.a.]: Mosby. ISBN 0-7234-3155-8.
- ^ Tendas, A; Niscola P, Fratoni S, Cupelli L, Morino L, Neri B, Ales M, Scaramucci L, Giovannini M, Barbati R, Dentamaro T, de Fabritiis P. (Dec 2010). "Koebner's phenomenon as a rare mechanism of acute myeloid leukemia dissemination: report of two cases with a brief overview.". Support Care Cancer 18 (12): 1495–7. doi:10.1007/s00520-010-1012-9.
- ^ In the anglicisation of a German word, double vowels are often substituted for the Germanic umlaut on single vowels. The transformation of "Köbner" to "Kooebner" is just such a case. In the English literature, the umlaut is simply dropped and you often find "Köbner" simply as "Kobner".
- ^ Elsevier, Dorland's Illustrated Medical Dictionary, Elsevier.
Sources
- Crissey JT, Parish LC, Holubar KH. Historical Atlas of Dermatology and Dermatologists. New York: The Parthenon Publishing Group, 2002.
- Paller A, Mancini A. Hurwitz Clinical Pediatric Dermatology. Philadelphia: Elsevier Saunders, 2002.
See also
|
Eponymous medical signs for integumentary system
|
|
| Skin |
- Asboe-Hansen sign
- Auspitz's sign
- Borsari's sign
- Braverman's sign
- Crowe sign
- Dennie–Morgan fold
- Darier's sign
- Fitzpatrick's sign
- Florid cutaneous papillomatosis
- Gottron's sign
- Hutchinson's sign
- Janeway lesion
- Kerr's sign
- Koebner's phenomenon
- Koplik spots
- Leser-Trelat sign
- Nikolsky's sign
- Pastia's sign
- Russell's sign
- Wickham striae
- Wolf's isotopic response
|
|
| Nails |
- Aldrich-Mees' lines
- Beau's lines
- Muehrcke's lines
- Terry's nails
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|
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Index of skin
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| Description |
- Anatomy
- Physiology
- Development
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| Disease |
- Infections
- Vesiculobullous
- Dermatitis and eczema
- Papulosquamous
- Urticaria and erythema
- Radiation-related
- Pigmentation
- Mucinoses
- Keratosis, ulcer, atrophy, and necrobiosis
- Vasculitis
- Fat
- Neutrophilic and eosinophilic
- Congenital
- Neoplasms and cancer
- nevi and melanomas
- epidermis
- dermis
- Symptoms and signs
- Terminology
|
|
| Treatment |
- Procedures
- Drugs
- antibiotics
- disinfectants
- emollients and protectives
- itch
- psoriasis
- other
- Wound and ulcer
|
|
Index of skin appendages
|
|
| Description |
- Anatomy
- Physiology
- Development
|
|
| Disease |
- Congenital
- Neoplasms and cancer
- Other
- Symptoms and signs
|
|
| Treatment |
|
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UpToDate Contents
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English Journal
- Nickel-induced Koebner phenomenon in chronic cutaneous lupus erythematosus.
- Lukacs A, Karpati S, Temesvari E.SourceDepartment of Dermatology, Venerology and Dermatooncology, Semmelweis University, Budapest, Hungary.
- Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG.J Dtsch Dermatol Ges.2011 Jun;9(6):475-6. doi: 10.1111/j.1610-0387.2010.07589.x. Epub 2010 Dec 30.
- PMID 21199366
Japanese Journal
- Induction of psoriasis and Koebner's phenomenon
- SINGH Sangeeta,SINGH Sanjay,SINGH Usha
- Journal of dermatology 37(6), 568-569, 2010-06-01
- NAID 10026546711
Related Links
- The Koebner phenomenon, also called the "Koebner response" or the "isomorphic response", refers to skin lesions appearing on lines of trauma. The Koebner phenomenon may result from either a linear exposure or irritation. ...
★リンクテーブル★
[★]
- 英
- Köebner phenomenon Koebner phenomenon, Kobner phenomenon Köbner phenomenon
- 同
- Köebner現象、Koebner現象、ケブナー現象、ケブネル徴候 Koebner sign、同形反応 isomorphic response
[show details]
- 健常皮膚部に摩擦や日光などの刺激を加えると病変を生じる現象
- 乾癬、扁平苔癬で陽性
国試
[★]
- 英
- Koebner phenomenon
- 関
- ケブナー現象、ケブネル現象
[★]
- 関
- consequence、event、phenomena、phenomenal