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- street names for ketamine (同)jet, super acid, special K, honey oil, green, cat valium, super C
- the 11th letter of the Roman alphabet (同)k
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- Kelvin / Kindergarten / (チェスの)King / kalium(ラテン語)(=potassium)の化学記号
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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/12/25 00:40:39」(JST)
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3-Deoxy-D-manno-oct-2-ulosonic acid
|  | 
| Names | 
| IUPAC name (4R,5R,6R,7R)-4,5,6,7,8-pentahydroxy-2-oxooctanoic acid | 
| Other names 2-Oxo-3-deoxy-D -mannooctonic acid
 2-Keto-3-Deoxy-D-manno-octonate2-Keto-3-deoxy-D-mannooctanoic acid
 3-Deoxy-D-manno-2-octulosonic acid
 
 
3-Deoxy-D -manno -octulosonic acid | 
| Identifiers | 
| CAS Number | 10149-14-1 linear form N | 
| Abbreviations | D-KDO; KDO; dOclA | 
| ChEBI | CHEBI:32817 Y | 
| ChemSpider | 106511 Y | 
| Jmol interactive 3D | Image Image
 | 
| PubChem | 445569 | 
| 
InChI 
InChI=1S/C8H14O8/c9-2-5(12)7(14)6(13)3(10)1-4(11)8(15)16/h3,5-7,9-10,12-14H,1-2H2,(H,15,16)/t3-,5-,6-,7-/m1/s1 Y Key: KYQCXUMVJGMDNG-SHUUEZRQSA-N Y
InChI=1/C8H14O8/c9-2-5(12)7(14)6(13)3(10)1-4(11)8(15)16/h3,5-7,9-10,12-14H,1-2H2,(H,15,16)/t3-,5-,6-,7-/m1/s1 Key: KYQCXUMVJGMDNG-SHUUEZRQBC | 
| 
SMILES 
O[C@@H]([C@@H]([C@@H](CC(C(O)=O)=O)O)O)[C@H](O)CO
O=C(O)C(=O)C[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO | 
| Properties | 
| Chemical formula | C8H14O8 | 
| Molar mass | 238.19 g·mol−1 | 
| 
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | 
| N verify (what is YN ?) | 
| Infobox references | 
|  |  | 
3-Deoxy-D-manno-oct-2-ulosonic acid or KDO is an ulosonic acid of a 2-ketooctose which is used by bacteria in the synthesis of lipopolysaccharides.[1] The D-manno prefix indicates that four chiral centers have the same configuration as D-mannose.
The cyclization of 3-deoxy-D-
manno-oct-2-ulosonic acid to the α-anomer. The chiral centers are indicated by asterisks.
 
 
 
References
- ^ Ghalambor, Mohammad Ali; Levine, Edward M.; Heath, Edward C. (1966). "The biosynthesis of cell wall lipopolysaccharide in Escherichia coli. III. The isolation and characterization of 3-deoxyoctulosonic acid". Journal of Biological Chemistry 241 (13): 3207–15. PMID 4287911. 
 
 
English Journal
- Synthesis of Chlamydia Lipopolysaccharide Haptens through the use of α-Specific 3-Iodo-Kdo Fluoride Glycosyl Donors.
- Pokorny B1, Kosma P.
- Chemistry (Weinheim an der Bergstrasse, Germany).Chemistry.2014 Oct 29. doi: 10.1002/chem.201405424. [Epub ahead of print]
- A scalable approach towards high-yielding and (stereo)selective glycosyl donors of the 2-ulosonic acid Kdo (3-deoxy-D-manno-oct-2-ulosonic acid) is a fundamental requirement for the development of vaccines against Gram-negative bacteria. Herein, we disclose a short synthetic route to 3-iodo Kdo fluo
- PMID 25354167
 
 
- Impact of conjugation chemistry on the immunogenicity of S. Typhimurium conjugate vaccines.
- Stefanetti G1, Rondini S1, Lanzilao L1, Saul A1, MacLennan CA1, Micoli F2.
- Vaccine.Vaccine.2014 Oct 21;32(46):6122-9. doi: 10.1016/j.vaccine.2014.08.056. Epub  2014 Sep 3.
- Salmonella Typhimurium is major cause of invasive nontyphoidal Salmonella disease in Africa. Conjugation of S. Typhimurium O-antigen to an appropriate carrier protein constitutes a possible strategy for the development of a vaccine against this disease, for which no vaccines are currently available.
- PMID 25192974
 
 
- Structural analysis of arabinose-5-phosphate isomerase from Bacteroides fragilis and functional implications.
- Chiu HJ, Grant JC, Farr CL, Jaroszewski L, Knuth MW, Miller MD, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wilson IA.
- Acta crystallographica. Section D, Biological crystallography.Acta Crystallogr D Biol Crystallogr.2014 Oct 1;70(Pt 10):2640-51. doi: 10.1107/S1399004714017052. Epub  2014 Sep 27.
- The crystal structure of arabinose-5-phosphate isomerase (API) from Bacteroides fragilis (bfAPI) was determined at 1.7 Å resolution and was found to be a tetramer of a single-domain sugar isomerase (SIS) with an endogenous ligand, CMP-Kdo (cytidine 5'-monophosphate-3-deoxy-D-manno-oct-2-ulosonate
- PMID 25286848
 
 
Japanese Journal
- 4-2-10 ホウ素ラムノガラクツロナンII複合体の機能に関する研究 : 特異的構成糖KDOの合成経路とその変異株の解析(4-2 植物の微量栄養素,2015年度京都大会)
 
- Sugar Activation for Production of Nucleotide Sugars as Substrates for Glycosyltransferases in Plants
 
 
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