ハウエル・ジョリー小体
WordNet
- invest with or as with a body; give body to (同)personify
- the external structure of a vehicle; "the body of the car was badly rusted"
- the main mass of a thing
- a natural object consisting of a dead animal or person; "they found the body in the lake" (同)dead body
- the entire structure of an organism (an animal, plant, or human being); "he felt as if his whole body were on fire" (同)organic structure, physical structure
- a collection of particulars considered as a system; "a body of law"; "a body of doctrine"; "a body of precedents"
- a group of persons associated by some common tie or occupation and regarded as an entity; "the whole body filed out of the auditorium"; "the student body"; "administrative body"
- an individual 3-dimensional object that has mass and that is distinguishable from other objects; "heavenly body"
- the central message of a communication; "the body of the message was short"
- United States inventor who built early sewing machines and won suits for patent infringement against other manufacturers (including Isaac M. Singer) (1819-1867) (同)Elias Howe
- Canadian hockey player who holds the record for playing the most games (born 1928) (同)Gordie Howe, Gordon Howe
- United States editor (1920-1993) (同)Irving Howe
- United States feminist who was active in the womens suffrage movement (1819-1910) (同)Julia Ward Howe
- a happy party
- United States writer and editor (1837-1920) (同)William Dean Howells
PrepTutorEJDIC
- 〈C〉『身体』,肉体 / 〈C〉(人・動物の)『胴体』 / 〈C〉)物の)『主要部』,本体《+『of』+『名』》 / 〈C〉(…の)『団体』,群れ:(…のたくさんの)集まり《+『of』+『名』》 / 〈C〉物体,…体 / 〈U〉実質;(酒・味などの)こく / 〈C〉《話》人
- (人が)『愉快な』,陽気な,上きげんの / (物事が)『楽しい』(pleasant);すてきな(nice) / 非常に(very) / (特に何かを得ようとして)〈人〉‘を'おだてる,うれしがらせる《+『名』+『along』(『up』)》
- 《英話》人;(特に)男
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/03/07 09:52:18」(JST)
[Wiki en表示]
A Howell–Jolly body (marked by arrow) within an erythrocyte
Howell–Jolly bodies are histopathological findings of basophilic nuclear remnants (clusters of DNA) in circulating erythrocytes. During maturation in the bone marrow late erythroblasts normally expel their nuclei, but in some cases a small portion of DNA remains. Its presence usually signifies a damaged or absent spleen.
It is named after Maxim Soucy-Proulx , William Henry Howell[1] and Justin Marie Jolly.[2][3]
Contents
- 1 Appearance
- 2 Causes
- 3 References
- 4 External links
Appearance
Howell–Jolly bodies: small, round inclusions seen in erythrocytes (peripheral blood – MGG stain)
This DNA appears as a basophilic (purple) spot on the otherwise eosinophilic (pink) erythrocyte on a standard H&E stained blood smear. These inclusions are normally removed by the spleen during erythrocyte circulation, but will persist in individuals with functional hyposplenia or asplenia.
Causes
Howell–Jolly bodies are seen with markedly decreased splenic function. Common causes include asplenia (post-splenectomy), trauma to the spleen, and autosplenectomy caused by sickle cell anemia. Other causes are radiation therapy involving the spleen, such as that used to treat Hodgkin lymphoma. Howell–Jolly bodies are also seen in: amyloidosis, severe hemolytic anemia, megaloblastic anemia, hereditary spherocytosis, heterotaxy with asplenia and myelodysplastic syndrome (MDS). Also can be seen in premature infants.
References
- ^ Howell, W. H. "The life-history of the formed elements of the blood, especially the red blood corpuscles". Journal of Morphology (New York) 4 (1): 57–116. doi:10.1002/jmor.1050040105.
- ^ synd/1596 at Who Named It?
- ^ Jolly, J (1908). Recherches sur la formation des globules rouges des mammifères (in French) 58. Paris: Comptes rendus de la Société de Biologie. pp. 528–531.
External links
- Digital Pathology, Brown University: Howell-Jolly Bodies
Abnormal clinical and laboratory findings for blood tests (R70–R79, 790)
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Red blood cells |
Size |
- Anisocytosis
- Macrocyte
- Microcyte
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Shape |
- Poikilocytosis
- membrane abnormalities:
- Acanthocyte
- Codocyte
- Ovalocyte
- Spherocyte
- Dacrocyte
- Echinocyte
- Schistocyte
- Degmacyte
- Drepanocyte
- Stomatocyte
- Knizocyte
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Hemoglobinization |
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Inclusion bodies |
- Developmental
- Howell–Jolly body
- Basophilic stippling
- Pappenheimer bodies
- Cabot rings
- Hemoglobin precipitation
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Other |
- Rouleaux
- Reticulocyte
- Elevated ESR
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Lymphocytes |
|
|
Small molecules |
Blood sugar |
- Hypoglycemia
- Hyperglycemia
- Prediabetes
- Impaired fasting glucose
- Impaired glucose tolerance
- Oxyhyperglycemia
|
|
Nitrogenous |
- Azotemia
- Hyperuricemia
- Hypouricemia
|
|
|
Proteins |
LFT |
- Elevated transaminases
- Elevated ALP
- Hypoproteinemia
|
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Other |
- Elevated cardiac markers
- Elevated alpha-fetoprotein
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Minerals |
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Pathogens/sepsis |
- Bacteremia
- Viremia
- Fungemia
- Parasitemia
- Algaemia
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Eponymous medical signs for hematology
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|
Inclusion bodies |
- Red blood cell
- Cabot rings
- Howell–Jolly body
- Pappenheimer bodies
- Heinz body
- Neutrophil
- Plasma cell
- Myeloblast
- Histiocyte
|
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Tests |
|
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Other |
- Arneth count
- Mentzer index
- Virchow's triad
- Anaemia
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UpToDate Contents
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English Journal
- Ex vivo resection of giant epidermoid cyst and vascularized partial splenic autotransplantation: 3.5-year follow-up.
- Wu G1, Zhao Q2, Wang W2, Chen D2, Shi H2, Zhao Z2, Wang M2, Ji G3, Zhang J4, Li Z5.
- Surgery.Surgery.2015 Dec;158(6):1734-7. doi: 10.1016/j.surg.2015.01.013. Epub 2015 Feb 21.
- PMID 25712201
- Quantification of Howell-Jolly body-like inclusions in ganciclovir toxicity using CellaVision DM96 analyser.
- Revol B1, Thiebaut-Bertrand A2,3, Carré M2, Bulabois CE2, Mossuz P3,4, Mondet J5,6.
- British journal of haematology.Br J Haematol.2015 Oct 12. doi: 10.1111/bjh.13784. [Epub ahead of print]
- PMID 26456312
- Rasburicase-induced Heinz body hemolytic anemia in a patient with chronic lymphocytic leukemia.
- Hrisinko MA, Chen YH.
- Blood.Blood.2015 Aug 6;126(6):826.
- PMID 26473196
Japanese Journal
- 症例報告 脾低形成を伴った劇症型肺炎球菌敗血症の一例
- Hyposplenia functions effectively to prevent infectious diseases and remove the abnormal red blood cells
- Ohsaka Manabu,Takaishi Masaaki,Yamanaka Mariko,Horie Ryoichi,Higashihara Masaaki
- 北里医学 32(3), 227-229, 2002-06-30
- … A 40-year-old healthy woman whose blood smear showed several red cell abnormalities, including Howell-Jolly bodies, revealed to have splenic hypoplasia (hyposplenia) by computed tomographic (CT) scan. …
- NAID 110004704590
- Age-Related Hematological Changes in Normal F344 Rats: during the Neonatal Period
- KOJIMA Sayuri,HARUTA Junko,ENOMOTO Akiko,FUJISAWA Hideki,HARADA Takanori,MAITA Keizo
- Experimental animals 48(3), 153-159, 1999-07
- … Microscopic examination of blood smears revealed that erythrocytes at birth had characteristic morphological features such as anisocytosis, polychromasia, basophilic stippling, Howell-Jolly body, and erythroblastosis. …
- NAID 10007347917
Related Links
- Symptoms, risk factors and treatments of Howell–Jolly body (Medical Condition) Howell–Jolly bodies are histopathological findings of basophilic nuclear remnants in circulating erythrocytes This ...
- Howell-Jolly body How·ell-Jol·ly body (hou'əl-zhô-lē') n. A spherical granule often observed in the stroma of a red blood cell, especially after a splenectomy.
Related Pictures
![Howell-Jollybodies are also encountered after splenectomy.](https://1mg.info/0/i/k/1112.jpg)
![Summary of Abnormal Red Blood Cell Morphologies and Disease States | Medical Laboratories](https://1mg.info/0/i/k/1113.jpg)
![Howell-Jolly bodies - 1.](https://1mg.info/0/i/k/1114.jpg)
![Howell Jolly Body found tonight | Lab stuff | Pinterest | Hematology](https://1mg.info/0/i/k/1115.jpg)
![Howell-Jolly Bodies - LabCE.com, Laboratory Continuing Education](https://1mg.info/0/i/k/1116.jpg)
★リンクテーブル★
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- 英
- Howell-Jolly body
- 同
- Howell-Jolly小体, 赤血球封入体、ジョリー小体 Jolly body
- 関
- 赤血球、erythrocyte inclusion
[★]
- 英
- erythrocyte inclusion
- 関
- ハウエル・ジョリー小体, Howell-Jolly body
[★]
- 英
- Howell-Jolly body
- 関
- ハウエル・ジョリー小体
[★]