Biochemical and biophysical research communications.Biochem Biophys Res Commun.2017 Dec 9;494(1-2):63-69. doi: 10.1016/j.bbrc.2017.10.084. Epub 2017 Oct 18.
PACT is required for MDA5-mediated immunoresponses triggered by Cardiovirus infection via interaction with LGP2.
Miyamoto M1, Komuro A2.
Biochemical and biophysical research communications.Biochem Biophys Res Commun.2017 Dec 9;494(1-2):227-233. doi: 10.1016/j.bbrc.2017.10.048. Epub 2017 Oct 12.
… We hypothesized that such agonists may have a cardio-suppressive effect in treating such disorders, therefore, we inoculated diabetic KKAy mice with encephalomyocarditis virus (EMCv) to induce a diabetic model with severe myocardial damage. … WY14643-treated mice, especially those in the WY14643-early group, had higher mortality than those in the vehicle-treated group (vehicle) in the first 5 days after EMCv inoculation. …
Acronym Definition EMCV Encephalomyocarditis Virus ... Infection with EMCV is associated with sporadic cases and outbreaks of myocarditis and encephalitis in domestic pigs, in numerous species of nonhuman primates, and in ...