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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/10/26 08:38:52」(JST)

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プロパニル（英: Propanil）は酸アミド系有機化合物の一種。除草剤として使用される。

用途

アメリカのロームアンドハース社 (Rohm and Haas) が開発した薬剤で、日本では1961年4月18日に農薬登録を受けた。水田やジャガイモ畑、桑畑、芝畑においてメヒシバ、ノビエ、ハコベなどに対する接触型除草剤として使用される^[2]。単剤の商品名は「DCPA」や「スタム」、カルバリルとの複合剤は「クサダウン」や「クサノンA」、ベンチオカルブとの複合剤は「サタニール」。

安全性

半数致死量（LD₅₀）はラットへの経口投与で840mg/kg、ラットへの経皮投与で5,000mg/kg^[3]。目に対する刺激性がある。摂取するとメトヘモグロビン血症を引き起こし、チアノーゼなどの症状が生じるほか中枢神経障害により錯乱や嘔吐、眼球突出などの症状を呈する。不純物として含まれるテトラクロロアゾベンゼンにより、塩素痤瘡（クロロアクネ、Chloracne）を引き起こすことがある^[2]。一日摂取許容量（ADI）は0.017mg/kg/day。カルバリルとの相乗効果で毒性が増し、1994年から1998年までの5年間のプロパニルによる死亡事例は単剤で2人、カルバリルとの複合剤で45人^[2]。不燃性だが加熱により分解し、塩化水素や窒素酸化物を含む有毒ガスを生じる^[4]。PRTR法による第一種指定化学物質に指定されており、ミジンコでの48時間半数致死濃度（LC₅₀）は6.7mg/L。

脚注

^ Merck Index, 11th Edition, 7814.
^ ^a ^b ^c 植村振作・河村宏・辻万千子・冨田重行・前田静夫著『農薬毒性の事典改訂版』三省堂、2002年。ISBN 978-4385356044。
^ 製品安全データシート（安全衛生情報センター）
^ 国際化学物質安全性カード

この項目は、化学に関連した書きかけの項目です。この項目を加筆・訂正などしてくださる協力者を求めています（プロジェクト:化学／Portal:化学）。

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[Wiki en表示]

The exterior of the Denver Center for the Performing Arts in 2009

The Denver Center for the Performing Arts (DCPA) is an organization in Denver, Colorado which provides a showcase for live theatre, a nurturing ground for new plays, a preferred stop on the Broadway touring circuit, acting classes for the community and rental facilities. It was founded in 1972 and dedicated to excellence in the arts.

The Denver Center for the Performing Arts is the largest tenant of the Denver Performing Arts Complex which is a four-block, 12-acre (49,000 m²) site containing ten performance spaces with over 10,000 seats. It is owned and partially operated by Arts and Venues Denver.

Both organizations were the vision of Donald Seawell. Finding himself at 14th and Curtis streets in downtown Denver one day and looking at the old Auditorium Theatre and the surrounding four blocks, Seawell had an idea for a first-class arts complex. Seawells original vision was much broader and included other entities (see Previous Entities below) which no longer are part of the Center.

Ground was broken in December 1974. By 1978 Boettcher Concert Hall — the nation's first in-the-round concert hall — was completed, along with an eight-story, 1,700-space parking garage. By 1979 the Auditorium Theatre had been renovated (and was completely renovated again in 2005, creating the state-of-the-art Ellie Caulkins Opera House inside of the historic Auditorium), two cabaret spaces had been added and the Helen G. Bonfils Theatre Complex opened with its four theatres: The Stage, Space, Source (now Jones) and Ricketson. The Temple Hoyne Buell Theatre was completed in 1991, the Seawell Grand Ballroom was added in 1998 and The Conservatory Theatre opened in 2002.

Entities of the DCPA

The Denver Center for the Performing Arts is currently the largest tenant of the Denver Performing Arts Complex. The Denver Center organizes, oversees, and presents work by the following entities:

The Denver Center Theatre Company (DCTC) was created in 1979 as the region's largest resident, professional theatre company. Under the leadership of Edward Payson Call (1979 to 1983), Donovan Marley (1984 to 2005) and Kent Thompson (2005 to the present), the Theatre Company has created an impressive body of classic and contemporary drama and world premieres. In acknowledgment of this work, the DCTC received the 1998 Tony Award for Outstanding Regional Theatre. Stage director Israel Hicks took on the challenge posed by Donovan Marley and directed August Wilson's entire 10-play Pittsburgh Cycle over a two-decade period starting in 1990.^[1]
Denver Center Attractions (DCA) was created by Robert Garner, presenter of national touring companies since 1961, and joined the Center in 1979. When Garner retired in 1992, his hand-picked successor was Randy Weeks (current DCPA president and executive director of DCA). Center Attractions presents Broadway touring shows and its impressive attendance record has made Denver a "pick" city. Disney selected Denver Center Attractions to host its pre-Broadway debut of The Little Mermaid, plus Disney's The Lion King, August: Osage County, Sunset Boulevard and the revival of Hello, Dolly starring Carol Channing among many others have chosen Denver to launch their national tours. DCA also produces cabaret including the original Denver-based comedy, Girls Only: The Secret Comedy of Women, and I Love You, You’re Perfect, Now Change, which ran for more than four years making it Denver's longest-running musical.
The Denver Center’s Education Department was started in October 1984 when the DCPA and the American National Theatre and Academy joined together to establish the National Theatre Conservatory, a three-year graduate acting program. The NTC will be phased out by 2012. The Denver Center Theatre Academy was added in 1991 as a community school for children and adults in a professional setting.
The Seawell Grand Ballroom is a 10,000-square-foot (930 m²) facility with a maximum capacity of 1,029 people. This pentagonal shaped room with panoramic views of the mountains can accommodate a variety of functions and features its own catering kitchen, freight elevator, tables, chairs, portable dance floor, movable platform staging and a state-of-the-art lighting, audio, video and projection systems. Epicurean Culinary Group is the exclusive caterer for the Ballroom.
Previous Entities which have since left the DCPA include Denver Center Media and Wilber James Gould Voice Center (a consortium member of the National Center for Voice and Speech). Denver Center Media was a full-service video and film production studio, was established in 1983 and received numerous international awards and Emmys for television production, direction and sound design. DCM productions have been broadcast nationally on PBS, cable and overseas networks. Productions include Top of the World, Colcannon, The Moscow String Quartet: At Play in America, Coors Field: Home at Last, Pamoja: A Coming Together and Memory of a Large Christmas. The Gould Voice Center was founded in 1983 and headed, until his death in 1994, by the noted otolaryngologist Dr. Wilbur James Gould and afterwords by world known speech scientist Ingo R. Titze. It was the only such facility in the world that is part of a performing arts organization. While these entities, along with the other entities, were at the DCPA, the entire conglomerate was unique in the world.

References

^ Weber, Bruce. "Israel Hicks, Director of August Wilson’s Cycle, Dies at 66", The New York Times, July 7, 2010. Accessed July 8, 2010.

External links

DCPA's official website
Denver Performing Arts Complex's official website
National Theatre Conservatory

Coordinates: 39°44′41″N 104°59′55″W / 39.744623°N 104.998476°W / 39.744623; -104.998476

English Journal

Synthesis of Ag doped calcium phosphate particles and their antibacterial effect as additives in dental glass ionomer cements.

Chen S1, Gururaj S1, Xia W2, Engqvist H1.
Journal of materials science. Materials in medicine.J Mater Sci Mater Med.2016 Nov;27(11):172. Epub 2016 Oct 4.
Developing dental restorations with enhanced antibacterial properties has been a constant quest for materials scientists. The aim of this study was to synthesize silver doped calcium phosphate particles and use them to improve antibacterial properties of conventional glass ionomer cement. The Ag dop
PMID 27704376

Biodiversity and agriculture in dynamic landscapes: Integrating ground and remotely-sensed baseline surveys.

Gillison AN1, Asner GP2, Fernandes EC3, Mafalacusser J4, Banze A5, Izidine S5, da Fonseca AR4, Pacate H6.
Journal of environmental management.J Environ Manage.2016 Jul 15;177:9-19. doi: 10.1016/j.jenvman.2016.03.037. Epub 2016 Apr 8.
Sustainable biodiversity and land management require a cost-effective means of forecasting landscape response to environmental change. Conventional species-based, regional biodiversity assessments are rarely adequate for policy planning and decision making. We show how new ground and remotely-sensed
PMID 27064732

Regulation of Growth, Cell Shape, Cell Division, and Gene Expression by Second Messengers (p)ppGpp and Cyclic Di-GMP in Mycobacterium smegmatis.

Gupta KR1, Baloni P2, Indi SS3, Chatterji D4.
Journal of bacteriology.J Bacteriol.2016 Apr 14;198(9):1414-22. doi: 10.1128/JB.00126-16. Print 2016 May.
The alarmone (p)ppGpp regulates transcription, translation, replication, virulence, lipid synthesis, antibiotic sensitivity, biofilm formation, and other functions in bacteria. Signaling nucleotide cyclic di-GMP (c-di-GMP) regulates biofilm formation, motility, virulence, the cell cycle, and other f
PMID 26903417

Japanese Journal

Effect of a calcium phosphate and fluoride paste on prevention of enamel demineralization

Dental Materials Journal 37(1), 65-70, 2018
NAID 130006322149

人間の障害物回避軌道の調査に基づいたファジィ推論による移動ロボットの障害物回避

ロボティクス・メカトロニクス講演会講演概要集 2016(0), 2A1-07a7, 2016
NAID 130007233770

フルオロアパタイトを形成するリン酸カルシウムセメントの理工学的特性

日本歯科保存学雑誌 59(6), 472-478, 2016
NAID 130005239823

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★リンクテーブル★

リンク元	「アニリン系除草剤中毒」
関連記事	「DC」

「アニリン系除草剤中毒」

プロパニル
	IUPAC名 N-(3,4-Dichlorophenyl)propanamide
	別称 3,4-ジクロロプロピオンアニリド; DCPA
識別情報
CAS登録番号	709-98-8
PubChem	4933
KEGG	C14229
	SMILES CCC(=O)NC1=CC(=C(C=C1)Cl)Cl;
特性
化学式	C9H9Cl2NO
モル質量	218.08 g/mol
外観	無色ないし白色の結晶
融点	91-93℃
沸点	350℃
水への溶解度	225 ppm
	特記なき場合、データは常温 (25 °C)・常圧 (100 kPa) におけるものである。

　　[★]

英: anilic herbicide poisoning
同: アミノベンゼン中毒、尿素系除草剤中毒
商: アラクロール、フェンメディファム、ブタクロール、プレチラクロール、メトラクロール、メフェナセット、リニュロン、DCMU、DCPA、IPC、MCC

「DC」

　　[★]

樹状細胞 dendritic cell
直流 direct current

同: dyskeratosis congenita

[1] Merck Index, 11th Edition, 7814.

[Sanseido-2] 植村振作・河村宏・辻万千子・冨田重行・前田静夫著『農薬毒性の事典改訂版』三省堂、2002年。ISBN 978-4385356044。

[jaish-3] 製品安全データシート（安全衛生情報センター）

[4] 国際化学物質安全性カード

[1] Weber, Bruce. "Israel Hicks, Director of August Wilson’s Cycle, Dies at 66", The New York Times, July 7, 2010. Accessed July 8, 2010.

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DCPA