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- See Cyclin-dependent protein kinases
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- certificate of deposit / (また『C.D.』)Civil Defense民間防衛
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- 1. マントル細胞リンパ腫の病理学 pathobiology of mantle cell lymphoma
- 2. 前立腺癌の分子生物学 molecular biology of prostate cancer
- 3. 巨核球の生物学と血小板の産生 megakaryocyte biology and the production of platelets
English Journal
- Macrophage inhibitory cytokine-1 stimulates proliferation of human umbilical vein endothelial cells by up-regulating cyclins D1 and E through the PI3K/Akt-, ERK-, and JNK-dependent AP-1 and E2F activation signaling pathways.
- Jin YJ, Lee JH, Kim YM, Oh GT, Lee H.SourceMedical and Bio-Material Research Center, Kangwon National University, Chunchon, Kangwon-do, 200-701, Republic of Korea; Department of Biological Sciences, College of Natural Sciences, Kangwon National University, Chunchon, Kangwon-do, 200-701, Republic of Korea.
- Cellular signalling.Cell Signal.2012 Aug;24(8):1485-95. Epub 2012 Mar 28.
- Macrophage inhibitory cytokine-1 (MIC-1) is highly associated with malignant human cancers and has been suggested to be involved in tumor angiogenesis. In the present study, we examined the effect of MIC-1 on endothelial cell proliferation to confirm the angiogenesis-promoting role of MIC-1. MIC-1 t
- PMID 22484283
- Perspective of Cyclin-dependent kinase 9 (CDK9) as a Drug Target.
- Krystof V, Baumli S, Furst R.SourceLaboratory of Growth Regulators, Palacký University, Šlechtitelů 11, 78371, Olomouc, Czech Republic. vladimir.krystof@upol.cz.
- Current pharmaceutical design.Curr Pharm Des.2012 Jul 1;18(20):2883-90.
- Deregulation of cyclin-dependent kinases (CDKs) has been associated with many cancer types and has evoked an interest in chemical inhibitors with possible therapeutic benefit. While most known inhibitors display broad selectivity towards multiple CDKs, recent work highlights CDK9 as the critical tar
- PMID 22571657
Japanese Journal
- 難治性てんかんを伴う神経発達障害の原因遺伝子CDKL5のシナプス伝達調節機構の解明に向けて
- 奥田 耕助,田中 輝幸
- 日本薬理学雑誌 145(4), 183-186, 2015
- … Cyclin-dependent kinase-like 5（CDKL5）遺伝子はXp22領域に位置し，mitogen-activated kinases（MAPKs）およびcyclin-dependent kinases（CDKs）と相同性のあるリン酸化酵素CDKL5をコードする．2003年以降，早期発症難治性てんかんを伴う重度発達障害である「X連鎖性ウエスト症候群」および「非典型レット症候群」の患児においてCDKL5遺伝子変異の報告が相次ぎ，CDKL5はてんかん・発達障害の原因遺伝子として注目を集めている．CDKL5遺伝子の主な …
- NAID 130005061553
- Inhibition of DNA binding of MCM2-7 complex by phosphorylation with cyclin-dependent kinases
- Moritani Mariko,Ishimi Yukio
- The journal of biochemistry 154(4), 363-372, 2013-10
- NAID 40019817570
- Protein phosphatases and their regulation in the control of mitosis
- Mochida Satoru,Tim Hunt,モチダ サトル,持田 悟
- EMBO Reports 13(3), 197-203, 2012-03
- … Thediscovery of cyclin dependent kinases (CDKs) and their mode of activation by their cyclin partners explained many important aspects of cell cycle control. …
- NAID 120005148222
Related Links
- All eukaryotes have multiple cyclins, each of which acts during a specific stage of the cell cycle. (In organisms with multiple CDKs, each CDK is paired with a specific cyclin.) All cyclins are named according to the stage at which ...
- CDプレーヤー部 チャンネル数 2チャンネルステレオ ラジオ部 受信周波数 ※1 AM:531～1,629kHz FM:76～90MHz テープレコーダー部 再生推奨テープ コンパクトカセットテープ90分以下 トラック方式 4トラック、2チャンネルステレオ 録音方式
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