関: Bak protein

WordNet

overwhelm with hilarity, pleasure, or admiration; "The comedian was so funny, he was killing me!"
cause to cease operating; "kill the engine"
destroy a vitally essential quality of or in; "Eating artichokes kills the taste of all other foods"
tire out completely; "The daily stress of her work is killing her"
the destruction of an enemy plane or ship or tank or missile; "the pilot reported two kills during the mission"
mark for deletion, rub off, or erase; "kill these lines in the Presidents speech" (同)obliterate, wipe_out
thwart the passage of; "kill a motion"; "he shot down the students proposal" (同)shoot down, defeat, vote down, vote out
be fatal; "cigarettes kill"; "drunken driving kills"
be the source of great pain for; "These new shoes are killing me!"
cause the death of, without intention; "She was killed in the collision of three cars"
cause to die; put to death, usually intentionally or knowingly; "This man killed several people when he tried to rob a bank"; "The farmer killed a pig for the holidays"
deprive of life; "AIDS has killed thousands in Africa"
hit with great force; "He killed the ball"
hit with so much force as to make a return impossible, in racket games; "She killed the ball"
having the same evolutionary origin but not necessarily the same function; "the wing of a bat and the arm of a man are homologous"
corresponding or similar in position or structure or function or characteristics; especially derived from an organism of the same species; "a homologous tissue graft"
the 2nd letter of the Roman alphabet (同)b
the blood group whose red cells carry the B antigen (同)type_B, group B
any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
a drug that neutralizes or counteracts the effects of another drug
a muscle that relaxes while another contracts; "when bending the elbow the triceps are the antagonist"

PrepTutorEJDIC

〈人・動物〉‘を'『殺す』,死亡させる / 〈植物〉‘を'枯らす / …‘を'だめにする,失わせる / 《話》…‘を'ひどく痛ませる(疲れさせる,不快にさせる) / 〈時間〉‘を'つぶす / 〈記事など〉‘を'没にする,握りつぶす / 人殺しをする / 殺すこと;(特に狩猟の)獲物をしとめること / (猟の)獲物
(位置・性質・構造などが)一致する,相応する;(生物の器官が)相同の
蛋白(たんばく)質
対立する人,敵対者,競争相手(opponent)

UpToDate Contents

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1. 慢性リンパ性白血病の病態生理および遺伝学的特徴 pathophysiology and genetic features of chronic lymphocytic leukemia
2. 前立腺癌の分子生物学 molecular biology of prostate cancer
3. 濾胞性リンパ腫の病理生物学 pathobiology of follicular lymphoma
4. 慢性骨髄性白血病の細胞生物学および分子生物学 cellular and molecular biology of chronic myeloid leukemia
5. びまん性大細胞型B細胞性リンパ腫および原発性縦隔大細胞型B細胞リンパ腫の病理学 pathobiology of diffuse large b cell lymphoma and primary mediastinal large b cell lymphoma

English Journal

Cyanidin-3-O-β-glucoside protects primary mouse hepatocytes against high glucose-induced apoptosis by modulating mitochondrial dysfunction and the PI3K/Akt pathway.

Jiang X1, Tang X2, Zhang P2, Liu G3, Guo H4.
Biochemical pharmacology.Biochem Pharmacol.2014 Jul 15;90(2):135-44. doi: 10.1016/j.bcp.2014.04.018. Epub 2014 May 10.
Apoptosis is an early event of steatohepatitis in non-alcoholic fatty liver disease (NAFLD), and an increase in oxidative stress induced by hyperglycemia has been linked to an acceleration of apoptosis in hepatocytes. Cyanidin-3-O-β-glucoside (C3G), a classic anthocyanin, has been reported to reduc
PMID 24821109

Halofuginone improves muscle-cell survival in muscular dystrophies.

Bodanovsky A1, Guttman N1, Barzilai-Tutsch H1, Genin O2, Levy O2, Pines M2, Halevy O3.
Biochimica et biophysica acta.Biochim Biophys Acta.2014 Jul;1843(7):1339-47. doi: 10.1016/j.bbamcr.2014.03.025. Epub 2014 Apr 2.
Halofuginone has been shown to prevent fibrosis via the transforming growth factor-β/Smad3 pathway in muscular dystrophies. We hypothesized that halofuginone would reduce apoptosis--the presumed cause of satellite-cell depletion during muscle degradation-in the mdx mouse model of Duchenne muscular
PMID 24703880

Airway mesenchymal cell death by mevalonate cascade inhibition: integration of autophagy, unfolded protein response and apoptosis focusing on Bcl2 family proteins.

Ghavami S1, Sharma P2, Yeganeh B2, Ojo OO2, Jha A2, Mutawe MM2, Kashani HH2, Los MJ3, Klonisch T4, Unruh H5, Halayko AJ6.
Biochimica et biophysica acta.Biochim Biophys Acta.2014 Jul;1843(7):1259-71. doi: 10.1016/j.bbamcr.2014.03.006. Epub 2014 Mar 15.
HMG-CoA reductase, the proximal rate-limiting enzyme in the mevalonate pathway, is inhibited by statins. Beyond their cholesterol lowering impact, statins have pleiotropic effects and their use is linked to improved lung health. We have shown that mevalonate cascade inhibition induces apoptosis and
PMID 24637330