アストロウイルス感染症
WordNet
- (medicine) the invasion of the body by pathogenic microorganisms and their multiplication which can lead to tissue damage and disease
- (phonetics) the alteration of a speech sound under the influence of a neighboring sound
- the pathological state resulting from the invasion of the body by pathogenic microorganisms
- (international law) illegality that taints or contaminates a ship or cargo rendering it liable to seizure
- moral corruption or contamination; "ambitious men are led astray by an infection that is almost unavoidable"
- an incident in which an infectious disease is transmitted (同)contagion, transmission
PrepTutorEJDIC
- 〈U〉(病気の)伝染;感染 / 〈C〉伝染病
English Journal
- Chicken astrovirus detected in hatchability problems associated with 'white chicks'.
- Smyth V1, Trudgett J, Wylie M, Jewhurst H, Conway B, Welsh M, Kaukonen E, Perko-Mäkelä P.
- The Veterinary record.Vet Rec.2013 Oct 26;173(16):403-4. doi: 10.1136/vr.f6393.
- PMID 24163046
- [Construction and expression of six deletion mutants of human astrovirus C-terminal nsP1a/4 protein].
- Zhao W1, Niu K2, Zhao J3, Jin YM3, Sui TT3, Wang W3.Author information 1Department of Experimental Animal, Institute of Basic Medicine, Liao Ning Medical University, Jinzhou 121200, China. zhaowei8072@163.com2First Affiliated Hospital of LiaoNing Medical University, Jinzhou 121200, China.3Department of Experimental Animal, Institute of Basic Medicine, Liao Ning Medical University, Jinzhou 121200, China.AbstractHuman astrovirus (HAstV) is one of the leading causes of actue virual diarrhea in infants. HAstV-induced epithdlial cell apoptosis plays an important role in the pathogenesis of HAstV infection. Our previous study indicated that HAstV non-structural protein nsPla C-terminal protein nsPla/4 was the major apoptosis functional protein and probably contained the main apoptosis domains. In order to screen for astrovirus encoded apoptotic protien, nsPla/4 and six turncated proteins, which possessed nsPla/4 protein different function domain ,were cloned into green fluorescent protein (GFP) vector pEG-FP-N3. After 24-72 h transfection, the fusion protein expression in BHK21 cells, was analysis by fluorescence microscope and Western blot. The results indicated seven fusion proteins were observed successfully in BHK21 cell after transfected for 24 h. Western blot analysis showed that the level of fusion protein expressed in BHK21 cells was increased significantly at 72h compared to 48h in transfected cells. The successful expression of deletion mutants of nsPla/4 protein was an important foundation to gain further insights into the function of apoptosis domains of nsPla/4 protein and it would also provide research platform to further confirm the molecule pathogenic mechanism of human astrovirus.
- Bing du xue bao = Chinese journal of virology / [bian ji, Bing du xue bao bian ji wei yuan hui].Bing Du Xue Bao.2013 Sep;29(5):548-54.
- Human astrovirus (HAstV) is one of the leading causes of actue virual diarrhea in infants. HAstV-induced epithdlial cell apoptosis plays an important role in the pathogenesis of HAstV infection. Our previous study indicated that HAstV non-structural protein nsPla C-terminal protein nsPla/4 was the m
- PMID 24386845
- Recently identified novel human astroviruses in children with diarrhea, China.
- Wang Y, Li Y, Jin Y, Li DD, Li X, Duan ZJ.KEYWORDS: Astrovirus, China, children, diarrhea, enteric infections, viruses
- Emerging infectious diseases.Emerg Infect Dis.2013 Aug;19(8):1333-5. doi: 10.3201/eid1908.121863.
- PMID 23880434
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