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1. アレルギー性鼻炎および結膜炎に対する補完代替療法 complementary and alternative therapies for allergic rhinitis and conjunctivitis

English Journal

Simultaneous determination of scopoletin, psoralen, bergapten, xanthotoxin, columbianetin acetate, imperatorin, osthole and isoimperatorin in rat plasma by LC-MS/MS for pharmacokinetic studies following oral administration of Radix Angelicae Pubescentis extract.

Chang YX, Zhang QH, Li J, Zhang L, Guo XR, He J, Zhang P, Ma L, Deng YR, Zhang BL, Gao XM.SourceTianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China; Tianjin Key Laboratory of Phytochemistry and Pharmaceutical Analysis, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China. Electronic address: tcmcyx@126.com.
Journal of pharmaceutical and biomedical analysis.J Pharm Biomed Anal.2013 Apr 15;77:71-5. doi: 10.1016/j.jpba.2012.12.031. Epub 2013 Jan 5.
A rapid and sensitive bioassay based on liquid chromatography tandem mass spectrometry (LC-MS/MS) has been developed and validated for the simultaneous determination of eight coumarins in rat plasma. The liquid-liquid extraction method with ethyl acetate was used to prepare the plasma samples after
PMID 23384552

A metabolic profiling analysis of the acute hepatotoxicity and nephrotoxicity of Zhusha Anshen Wan compared with cinnabar in rats using (1)H NMR spectroscopy.

Wang H, Bai J, Chen G, Li W, Xiang R, Su G, Pei Y.SourceDepartment of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, PR China.
Journal of ethnopharmacology.J Ethnopharmacol.2013 Mar 27;146(2):572-80. doi: 10.1016/j.jep.2013.01.026. Epub 2013 Jan 31.
ETHNOPHARMACOLOGICAL RELEVANCE: Zhusha Anshen Wan (ZSASW), a traditional Chinese medicine (TCM) prescription, composed of cinnabar (cinnabaris), Coptidis Rhizoma (Coptis chinensis French.), Angelicae Sinensis Radix (Angelica sinensis (oliv.) Diels), uncooked Rehmanniae Radix (Rehmannia glutinosa Lib
PMID 23376283

Absorptive constituents and their metabolites in drug-containing urine samples from Wuzhishan miniature pigs orally administered with Buyang Huanwu decoction.

Yang DH, Ren XL, Xu F, Ma XQ, Liu GX, Li CH, Li C, Cai SQ.SourceState Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, People's Republic of China.
Journal of natural medicines.J Nat Med.2013 Mar 21. [Epub ahead of print]
Buyang Huanwu decoction (BYHWD), a famous traditional Chinese medicine prescription for the treatment of cerebrovascular diseases, is composed of seven commonly used Chinese herbs-Astragali Radix, Angelicae Sinensis Radix, Paeoniae Radix Rubra, Chuanxiong Rhizoma, Carthami Flos, Persicae Semen and P
PMID 23516044

本田豊,砂川正隆,米山早苗 [他],池本英志,中西孝子,岩波弘明,須賀大樹,石川慎太郎,石野尚吾,久光正
日本東洋医学雑誌 64(2), 78-85, 2013
抑肝散は，神経症，不眠症，小児の夜泣き，小児疳症など虚弱体質で神経高ぶるものの症状などに適用されている。近年，頭痛や神経障害性疼痛などの疼痛性疾患に対する有効性も報告されているが，これらの作用機序は十分に解明されてはいない。本研究では，アジュバント関節炎（AA）モデルラットを作製し，慢性炎症性疼痛ならびに疼痛に伴うストレスに対する有効性を検証した。AA モデルラットでは，疼痛閾値の低下と精神的スト …
NAID 130003369917

Gas chromatography-mass spectrometry based metabolic profiling for the identification of discrimination markers of Angelicae Radix and its application to gas chromatography-flame ionization detector system(METHODS)

Kobayashi Shizu,Putri Sastia Prama,Yamamoto Yutaka [他],Donghyo Kang,Bamba Takeshi,Fukusaki Eiichiro
Journal of bioscience and bioengineering 114(2), 232-236, 2012-08
… Gas chromatography (GC)-based metabolomics technologies were applied for quality control of Angelicae Radix, an herbal medicine commonly used in Japan and China. … Radix. … Radix were successfully classified using metabolic profiling and the orthogonal projections to latent structures-discriminant analysis (OPLS-DA) technique. … Radix. …
NAID 110009495435

三浦於菟,河野吉成,板倉英俊 [他],田中耕一郎,植松海雲,奈良和彦,橋口亮,吉田和裕,桑名一央,塚田心平,土屋喬,福島厚,小菅孝明,斉藤輝夫
日本東洋醫學雜誌 = Japanese journal of oriental medicine 61(5), 740-745, 2010-07-20
… The use of Huan qi (Radix Astragali sen Hedysari) is based on the Han-Sui dynasty medical principle that night sweats are mainly caused by Deficiency of Yang. … Herbs to enrich the lood and Yin, Dang gui (Radix Angelicae Sinesis), Seng di huang (Radix Remannia), Shu di huang Radix Rehmannia preparata) were later added because Son dynasty physicians mentioned that Yin deficiency caused night sweats. …
NAID 10026567495