WordNet

(medicine) the invasion of the body by pathogenic microorganisms and their multiplication which can lead to tissue damage and disease
(phonetics) the alteration of a speech sound under the influence of a neighboring sound
the pathological state resulting from the invasion of the body by pathogenic microorganisms
(international law) illegality that taints or contaminates a ship or cargo rendering it liable to seizure
moral corruption or contamination; "ambitious men are led astray by an infection that is almost unavoidable"
an incident in which an infectious disease is transmitted (同)contagion, transmission

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〈U〉(病気の)伝染;感染 / 〈C〉伝染病

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/08/31 17:39:05」(JST)

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Actinobacillus is a genus of Gram-negative, immotile and nonspore-forming, oval to rod-shaped bacteria occurring as parasites or pathogens in mammals, birds, and reptiles.^[1] It is a member of the Pasteurellaceae family.^[2] The bacteria are facultatively aerobic or anaerobic, capable of fermenting carbohydrates (without production of gas), and of reducing nitrates. The genomic DNA contains between 40 and 47 mol % guanine plus cytosine.

Actinobacillus (Pasteurella) ureae and A. hominis occur in the respiratory tracts of healthy humans and may be involved in the pathogenesis of sinusitis, bronchopneumonia, and meningitis. A. actinomycetemcomitans occurs in the human oral microflora,^[3] and together with anaerobic or capnophilic organisms (HACEK group organisms) may cause endocarditis. Actinobacilli are susceptible to most antibiotics of the beta-lactam family, aminoglycosides, tetracyclines, chloramphenicol, and many other antibacterial chemotherapeutics.

An analysis of A. actinomycetemcomitans indicated it was monophyletic with Haemophilus aphrophilus and H. segnis, and it was proposed that they be reclassified as a new genus, Aggregatibacter (from the Latin, "aggregare", meaning "to come together").^[4]^[5]

References

^ Chung et al. (2008). "Actinobacillus pleuropneumoniae". Pasteurellaceae: Biology, Genomics and Molecular Aspects. Caister Academic Press. ISBN 978-1-904455-34-9.
^ Kuhnert P; Christensen H (editors). (2008). Pasteurellaceae: Biology, Genomics and Molecular Aspects. Caister Academic Press. ISBN 978-1-904455-34-9.
^ Rogers A H (editor). (2008). Molecular Oral Microbiology. Caister Academic Press. ISBN 978-1-904455-24-0.
^ Nørskov-Lauritsen N, Kilian M (September 2006). "Reclassification of Actinobacillus actinomycetemcomitans, Haemophilus aphrophilus, Haemophilus paraphrophilus and Haemophilus segnis as Aggregatibacter actinomycetemcomitans gen. nov., comb. nov., Aggregatibacter aphrophilus comb. nov. and Aggregatibacter segnis comb. nov., and emended description of Aggregatibacter aphrophilus to include V factor-dependent and V factor-independent isolates". Int. J. Syst. Evol. Microbiol. 56 (Pt 9): 2135–46. doi:10.1099/ijs.0.64207-0. PMID 16957111.
^ Nørskov-Lauritsen, N (Apr 2014). "Classification, identification, and clinical significance of haemophilus and aggregatibacter species with host specificity for humans.". Clinical Microbiology Reviews 27 (2): 214–40. doi:10.1128/CMR.00103-13. PMC 3993099. PMID 24696434.

UpToDate Contents

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1. 歯性感染症の疫学、病因、および臨床症状 epidemiology pathogenesis and clinical manifestations of odontogenic infections
2. 心臓埋め込み型電気デバイスの感染 infections involving cardiac implantable electronic devices
3. 歯性感染症の合併症、診断、および治療 complications diagnosis and treatment of odontogenic infections
4. 頚部顔面の放線菌症 cervicofacial actinomycosis
5. 固有弁心内膜炎の抗菌療法 antimicrobial therapy of native valve endocarditis

English Journal

Actinobacillus equuli ssp. haemolyticus in a semi-occlusively treated horse bite wound in a 2-year-old girl.

Schröttner P, Schultz J, Rudolph W, Gunzer F, Thürmer A, Fitze G, Jacobs E.SourceInstitute of Medical Microbiology and Hygiene, Faculty of Medicine, Universitätsklinikum Carl-Gustav-Carus, Dresden, Germany.
German medical science : GMS e-journal.Ger Med Sci.2013 Sep 24;11:Doc14. doi: 10.3205/000182.
in

English, GermanWir berichten über den Nachweis von Actinobacillus equuli ssp. haemolyticus aus Wundabstrichen eines 2 Jahre alten Mädchens, welches sich wegen eines Pferdebisses in der Klinik vorstellte. Diese Verletzung führte zu einer teilweisen Amputation der distalen Phalanx ihres rech

PMID 24068980

Identification of proteins of Propionibacterium acnes for use as vaccine candidates to prevent infection by the pig pathogen Actinobacillus pleuropneumoniae.

Li L, Sun C, Yang F, Yang S, Feng X, Gu J, Han W, Langford PR, Lei L.SourceCollege of Animal Science and Veterinary Medicine, Jinlin University, Changchun 130062, PR China; Section of Paediatrics, Imperial College London, St. Mary's Campus, London W2 1PG, United Kingdom.
Vaccine.Vaccine.2013 Sep 16. pii: S0264-410X(13)01166-3. doi: 10.1016/j.vaccine.2013.08.054. [Epub ahead of print]
Actinobacillus pleuropneumoniae is the causative agent of acute and chronic pleuroneumonia that is responsible for substantial morbidity and mortality in the pig industry. New improved vaccines that can protect against all serotypes and prevent colonization are required. In a previous study we showe
PMID 24051157

The RNA chaperone Hfq promotes fitness of Actinobacillus pleuropneumoniae during porcine pleuropneumonia.

Subashchandrabose S, Leveque RM, Kirkwood RN, Kiupel M, Mulks MH.SourceComparative Medicine and Integrative Biology Program, Michigan State University, East Lansing, Michigan, USA.
Infection and immunity.Infect Immun.2013 Aug;81(8):2952-61. doi: 10.1128/IAI.00392-13. Epub 2013 Jun 3.
Actinobacillus pleuropneumoniae is the etiological agent of porcine pleuropneumonia, an economically important disease of pigs. The hfq gene in A. pleuropneumoniae, encoding the RNA chaperone and posttranscriptional regulator Hfq, is upregulated during infection of porcine lungs. To investigate the
PMID 23732171

Japanese Journal

Macrophages largely contribute to heterologous anti-Propionibacterium acnes antibody-mediated protection from Actinobacillus pleuropneumoniae infection in mice

Ma Qiuyue,Sun Changjiang,Yang Feng [他]
Microbiology and immunology 59(3), 166-173, 2015-03
NAID 40020416318

ユーカリ葉抽出物による日和見感染，歯周疾患，う蝕予防についての検討　重症心身障害児・者への口腔ケアのために

河瀬聡一朗,宮沢裕夫,平井要,金子仁子
松本歯学 38(1), 12-21, 2012-04-30
… In children and adults with severe psychosomatic disorders accompanied by eating and swallowing disorders, saliva contains a high number of bacteria, particularly after assisted brushing, and retention of the etiologic agent of opportunistic infection increases the risk of aspiration pneumonia. …
NAID 120004631691

豚の全身性 Actinobacillus suis 感染症

佐々木羊介,Kabali Emmanuel,芝原友幸 [他],小林秀樹,清水稚恵,森田大輔,久保正法
日本獣医師会雑誌 = Journal of the Japan Veterinary Medical Association 64(5), 381-384, 2011-05-20
… た好中球が層状に取り巻く像が確認された．これらの病変部にはグラム陰性菌塊が認められた．同様の病変は肝臓、脾臓、腸間膜および大脳にも認められた．免疫組織化学的に、このグラム陰性桿菌は抗Actinobacillus suis血清に対して陽性反応を示した．病変部から病原菌の分離培養ができなかったため、ホルマリン固定パラフィン包埋組織切片からDNAを分離した．16S rRNA遺伝子の一部を増幅・塩基配列解析した結果、 …
NAID 10029384030

「アクチノバチルス感染症」

Haemophilus
	Actinobacillus suis
Scientific classification
Kingdom:	Bacteria
Phylum:	Proteobacteria
Class:	Gammaproteobacteria
Order:	Pasteurellales
Family:	Pasteurellaceae
Genus:	Actinobacillus; Brumpt 1910
Species
	A. actinomycetemcomitans; A. arthritidis; A. capsulatus; A. delphinicola; A. equuli; A. hominis; A. indolicus; A. lignieresii; A. minor; A. muris; A. pleuropneumoniae; A. porcinus; A. rossii; A. scotiae; A. seminis; A. succinogenes; A. suis; A. ureae

　　[★]

英: Actinobacillus infection

「Actinobacillus」

　　[★]

アクチノバチルス、アクチノバシラス、アクチノバチラス、アクチノバチルス属、アクチノバチラス属、アクチノバシラス属、Actinobacillus属

「infection」

　　[★]

n.

感染、伝染、感染症

関: contagion、infect、infectious disease、infestation、transmission、transmit

[Chung-1] Chung et al. (2008). "Actinobacillus pleuropneumoniae". Pasteurellaceae: Biology, Genomics and Molecular Aspects. Caister Academic Press. ISBN 978-1-904455-34-9.

[KuhnertChristensen-2] Kuhnert P; Christensen H (editors). (2008). Pasteurellaceae: Biology, Genomics and Molecular Aspects. Caister Academic Press. ISBN 978-1-904455-34-9.

[AnthonyHRogers-3] Rogers A H (editor). (2008). Molecular Oral Microbiology. Caister Academic Press. ISBN 978-1-904455-24-0.

[4] Nørskov-Lauritsen N, Kilian M (September 2006). "Reclassification of Actinobacillus actinomycetemcomitans, Haemophilus aphrophilus, Haemophilus paraphrophilus and Haemophilus segnis as Aggregatibacter actinomycetemcomitans gen. nov., comb. nov., Aggregatibacter aphrophilus comb. nov. and Aggregatibacter segnis comb. nov., and emended description of Aggregatibacter aphrophilus to include V factor-dependent and V factor-independent isolates". Int. J. Syst. Evol. Microbiol. 56 (Pt 9): 2135–46. doi:10.1099/ijs.0.64207-0. PMID 16957111.

[5] Nørskov-Lauritsen, N (Apr 2014). "Classification, identification, and clinical significance of haemophilus and aggregatibacter species with host specificity for humans.". Clinical Microbiology Reviews 27 (2): 214–40. doi:10.1128/CMR.00103-13. PMC 3993099. PMID 24696434.

リンク元	「アクチノバチルス感染症」
関連記事	「Actinobacillus」「infection」

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Actinobacillus infection