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1. ビタミンB12および葉酸欠乏症の生理学 physiology of vitamin b12 and folate deficiency
2. メトトレキサートを使用した関節リウマチ治療 use of methotrexate in the treatment of rheumatoid arthritis
3. ホモシステインの概要 overview of homocysteine
4. 腎移植レシピエントにおける心血管疾患の危険因子 risk factors for cardiovascular disease in the renal transplant recipient
5. ビタミンB12および葉酸欠乏症の病因および臨床症状 etiology and clinical manifestations of vitamin b12 and folate deficiency

Methylenetetrahydrofolate reductase C677T and methionine synthase A2756G polymorphisms influence on leukocyte genomic DNA methylation level.

Weiner AS1, Boyarskikh UA, Voronina EN, Mishukova OV, Filipenko ML.
Gene.Gene.2014 Jan 1;533(1):168-72. doi: 10.1016/j.gene.2013.09.098. Epub 2013 Oct 5.
Methionine synthase (MTR) and methylenetetrahydrofolate reductase (MTHFR) enzymes are involved in the metabolism of methyl groups, and thus have an important role in the maintenance of proper DNA methylation level. In our study we aimed to evaluate the effect of the polymorphism A2756G (rs1805087) i
PMID 24103477

Genetic polymorphisms in MTHFR (C677T, A1298C), MTR (A2756G) and MTRR (A66G) genes associated with pathological characteristics of prostate cancer in the Ecuadorian population.

López-Cortés A1, Jaramillo-Koupermann G, Muñoz MJ, Cabrera A, Echeverría C, Rosales F, Vivar N, Paz-y-Miño C.
The American journal of the medical sciences.Am J Med Sci.2013 Dec;346(6):447-54. doi: 10.1097/MAJ.0b013e3182882578.
INTRODUCTION: The methylenetetrahydrofolate reductase (MTHFR), methionine synthase (MTR) and MTR reductase (MTRR) enzymes act in the folate metabolism, which is essential in methylation and synthesis of nucleic acids. The single nucleotide polymorphisms, MTHFR C677T, A1298C, MTR A2756G and MTRR A66G
PMID 23459165

Role of polymorphism of methyltetrahydrofolate-homocysteine methyltransferase (MTR) A2756G and breast cancer risk.

Hosseini M.
Polish journal of pathology : official journal of the Polish Society of Pathologists.Pol J Pathol.2013 Oct;64(3):191-5.
Breast cancer (BC) is one of the most common causes of death among women, and second in Iran. The objectives of this study were to determine the frequency of methyltetrahydrofolate-homocysteine methyltransferase (MTR) 2756 gene polymorphism in patients with breast cancer. For the first time, we eval
PMID 24166605