ラミブジン lamivudine


  1. a nucleoside reverse transcriptase inhibitor that is very effective in combination with zidovudine in treating AIDS and HIV (同)3TC

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/04/26 01:59:48」(JST)

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English Journal

  • Isolation and identification of an anti-hepatitis B virus compound from Hydrocotyle sibthorpioides Lam.
  • Huang Q, Zhang S, Huang R, Wei L, Chen Y, Lv S, Liang C, Tan S, Liang S, Zhuo L, Lin X.SourceThe First Affiliated Hospital of Guangxi University of Chinese Medicine, Nanning 530023, China.
  • Journal of ethnopharmacology.J Ethnopharmacol.2013 Nov 25;150(2):568-75. doi: 10.1016/j.jep.2013.09.009. Epub 2013 Sep 16.
  • ETHNOPHARMACOLOGICAL RELEVANCE: Hydrocotyle sibthorpioides (Apiaceae) have been used as a folk remedy for the treatment of fever, edema, detoxication, throat pain, psoriasis and hepatitis B virus infections in China. The aim of this study is to isolate and identify an anti-HBV compound from this her
  • PMID 24051027
  • Outcomes by Sex following Treatment Initiation with Atazanavir plus Ritonavir or Efavirenz with Abacavir/Lamivudine or Tenofovir/Emtricitabine.
  • Smith KY, Tierney C, Mollan K, Venuto CS, Budhathoki C, Ma Q, Morse GD, Sax P, Katzenstein D, Godfrey C, Fischl M, Daar ES, Collier AC; ACTG 5202 Study Team.SourceRush University Medical Center.
  • Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.Clin Infect Dis.2013 Nov 18. [Epub ahead of print]
  • Background. To evaluate treatment responses to atazanavir plus ritonavir or efavirenz in initial antiretroviral regimens among women and men, and determine if treatment outcomes differ by sex. Methods. Randomized trial of open label atazanavir plus ritonavir or efavirenz combined with abacavir/l
  • PMID 24253247
  • The Connection Domain Mutation N348I in HIV-1 Reverse Transcriptase Enhances Resistance to Etravirine and Rilpivirine but Restricts the Emergence of the E138K Resistance Mutation by Diminishing Viral Replication Capacity.
  • Xu HT, Colby-Germinario SP, Oliveira M, Han Y, Quan Y, Zanichelli V, Wainberg MA.SourceMcGill University AIDS Centre, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Quebec, Canada.
  • Journal of virology.J Virol.2013 Nov 13. [Epub ahead of print]
  • Clinical resistance to rilpivirine (RPV), a novel non-nucleoside reverse transcriptase inhibitor (NNRTI), is associated a mutation at position E138K in RT together with an M184I/V mutation that confers resistance against emtricitabine (FTC), a nucleoside RT inhibitor (NRTI) that is given together wi
  • PMID 24227862

Japanese Journal

  • Pure Red Cell Aplasia Induced by Lamivudine without the Influence of Zidovudine in a Patient Infected with Human Immunodeficiency Virus
  • Nakamura Kiwamu,Tateyama Masao,Tasato Daisuke,Haranaga Shusaku,Tamayose Maki,Yara Satomi,Higa Futoshi,Fujita Jiro
  • Internal Medicine 53(15), 1705-1708, 2014
  • We herein report the case of a patient with human immunodeficiency virus infection and acquired immune deficiency syndrome who was diagnosed with drug-induced pure red cell aplasia consequent to lamiv …
  • NAID 130004678378
  • Molecular analysis of the genes causing recessive demyelinating Charcot-Marie-Tooth disease in Japan
  • HAYASHI Makiko,ABE Akiko,MURAKAMI Tatsufumi,YAMAO Satoshi,ARAI Hidee,HATTORI Hideji,IAI Mizue,WATANABE Kyoko,OKA Nobuyuki,CHIDA Keiji,KISHIKAWA Yumiko,HAYASAKA Kiyoshi
  • Journal of human genetics 58(5), 273-278, 2013-05-01
  • NAID 10031177222
  • Molecular analysis of the genes causing recessive demyelinating Charcot-Marie-Tooth disease in Japan
  • Hayashi Makiko,Abe Akiko,Murakami Tatsufumi [他]
  • Journal of human genetics 58(5), 273-278, 2013-05
  • NAID 40019651872

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lamivudine, 3TC



  • 核酸系逆転写酵素阻害薬。
  • 細胞内でリン酸化され,三リン酸となりHIVのDNA鎖の伸長反応を停止することにより,抗ウイルス効果を発現する。







  [★] ラミブジン 3TC